Works matching DE "CYTOTOXIC T cells"

Results: 5000

The pivotal role of tertiary lymphoid structures in the tumor immune microenvironment.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1616904

By:

Liu, Chengsen;
Cao, Jiandong

Publication type:

Article

Tumor-infiltrating lymphocytes in cancer immunotherapy: from chemotactic recruitment to translational modeling.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1601773

By:

Kraja, Fatjona Pupuleku;
Jurisic, Vladimir B.;
Hromić-Jahjefendić, Altijana;
Rossopoulou, Nafsika;
Katsila, Theodora;
Mirjacic Martinovic, Katarina;
De Las Rivas, Javier;
Diaconu, Carmen Cristina;
Szöőr, Árpád

Publication type:

Article

Inhibitory effect of recombinant BCG containing the fusion gene BFNA on EB virus-positive tumors.

Published in:

Applied Microbiology & Biotechnology, 2025, v. 109, n. 1, p. 1, doi. 10.1007/s00253-025-13528-9

By:

Huang, Shuo;
Shao, Shuyang;
Fan, Liding;
Wang, Junying;
Meng, Furen;
Guan, Siyuan;
Wang, Changhao;
Liu, Ang;
Wang, Yuanhui;
Xue, Qingjie

Publication type:

Article

PSMB10 maintains the stemness of chemotherapeutic drug-resistant leukemia cells by inhibiting senescence and cytotoxic T lymphocyte-mediated killing in a ubiquitinated degradation manner.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03420-9

By:

Ma, Xiao;
Li, Yingnan;
Wang, Di;
Niu, Jialan;
Li, Qian;
Chen, Ying;
Wang, Mengyuan;
Wen, Jin;
Liao, Chenxi;
Wang, Nan;
Zhang, Xiaolan;
Chang, Jiwei;
Yang, Jiayi;
Li, Lei;
Zou, Jing;
Peng, Danyue;
Liu, Lingbo

Publication type:

Article

Tumor microenvironment governs the prognostic landscape of immunotherapy for head and neck squamous cell carcinoma: A computational model-guided analysis.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.pcbi.1013127

By:

Bhattacharya, Priyan;
Linnenbach, Alban;
South, Andrew P.;
Martinez-Outschoorn, Ubaldo;
Curry, Joseph M.;
Johnson, Jennifer M.;
Harshyne, Larry A.;
Mahoney, Mỹ G.;
Luginbuhl, Adam J.;
Vadigepalli, Rajanikanth

Publication type:

Article

Reverse vaccinology-based design of multivalent multiepitope mRNA vaccines targeting key viral proteins of Herpes Simplex Virus type-2.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1586271

By:

Suneesh, N. S.;
Dhotre, Kishore;
Mahajan, Pratik;
Dass, Debashree;
Banerjee, Anwesha;
Siddiqi, Nikhat J.;
Malik, Abdul;
Joshi, Manali;
Khan, Abdul Arif;
Nema, Vijay;
Mukherjee, Anupam

Publication type:

Article

Development of caninized anti-CTLA-4 antibody as salvage combination therapy for anti-PD-L1 refractory tumors in dogs.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1570717

By:

Maekawa, Naoya;
Konnai, Satoru;
Watari, Kei;
Takeuchi, Hiroto;
Nakanishi, Takeshi;
Tachibana, Taro;
Hosoya, Kenji;
Kim, Sangho;
Kinoshita, Ryohei;
Owaki, Ryo;
Yokokawa, Madoka;
Kagawa, Yumiko;
Takagi, Satoshi;
Deguchi, Tatsuya;
Ohta, Hiroshi;
Kato, Yukinari;
Yamamoto, Satoshi;
Yamamoto, Keiichi;
Suzuki, Yasuhiko;
Okagawa, Tomohiro

Publication type:

Article

Multi-Epitope Vaccine Design Targeting O6-methylguanine-DNA Methyltransferase (MGMT) in Glioblastoma Multiforme.

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 9, p. 1169, doi. 10.1142/S2737416525500152

By:

Alamri, Abdulaziz;
Algarzae, Norah Khaled;
Alzharani, Areej Ali;
Alenad, Amal;
Khan, Mohd Shahnawaz

Publication type:

Article

Integrative machine learning identifies robust inflammation-related diagnostic biomarkers and stratifies immune-heterogeneous subtypes in Kawasaki disease.

Published in:

Pediatric Rheumatology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12969-025-01114-2

By:

Wang, Xia;
Zhang, Lin

Publication type:

Article

In Silico Design, Optimization, and Evaluation of a Multi-Epitope Vaccine Targeting the Clostridium perfringens Collagen Adhesin Protein.

Published in:

Microorganisms, 2025, v. 13, n. 5, p. 1147, doi. 10.3390/microorganisms13051147

By:

Chundru, Dhiraj;
Bhattrai, Shailes;
Timilsina, Madhusudan;
Lillehoj, Hyun;
Sun, Zhifeng;
Ghanem, Mostafa;
Li, Charles

Publication type:

Article

The value of GULP1 in cancer prognosis and immunotherapy, validated from pan-cancer analysis to pancreatic cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99909-6

By:

Wang, Wangbiao;
Li, Yuxiang;
Li, Shiang;
Lin, Feng;
Guo, Jun;
Liu, Fuzhong;
Abudusaimaiti, Gulinaizaier;
Liu, Junyuan;
Sun, Gang

Publication type:

Article

Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451666

By:

van den Dijssel, Jet;
Menon, Tejas;
McQuilten, Hayley A.;
Eltherington, Oliver;
Gonzalez, Alexis;
Baghdasarian, Sevana;
Soemardy, Citradewi;
Di Carlo, Dino;
van Gisbergen, Klaas P.J.M.;
ten Brinke, Anja;
van de Sandt, Carolien E.

Publication type:

Article

Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells.

Published in:

European Journal of Immunology, 2025, v. 55, n. 5, p. 1, doi. 10.1002/eji.202451529

By:

Schneider Revueltas, Emilia;
Ferreira‐Gomes, Marta;
Guerra, Gabriela Maria;
Durek, Pawel;
Heinrich, Frederik;
Casanovas Subirana, Anna;
Tokoyoda, Koji;
Dong, Jun;
Reinke, Simon;
Hardt, Sebastian;
Hipfl, Christian;
Dörner, Thomas;
Perka, Carsten;
Hoffmann, Ute;
Chang, Hyun‐Dong;
Mashreghi, Mir‐Farzin;
Radbruch, Andreas

Publication type:

Article

Tumor-specific CXCR6 positive precursor CD8+ T cells mediate tumor control in metastatic melanoma.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 3, p. 693, doi. 10.1007/s13402-025-01040-1

By:

Song, Yang;
Chen, Ji;
Zhang, Yaqin;
Wu, Ning;
Zhu, Yongjun;
Chen, Gang;
Miao, Feng;
Chen, Zhiming;
Wang, Yiqing

Publication type:

Article

Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1521700

By:

Asadollahi, Elahe;
Zomorodipour, Alireza;
Soheili, Zahra-Soheila;
Jahangiri, Babak;
Sadeghizadeh, Majid

Publication type:

Article

Interleukin-15Rα-Sushi-Fc Fusion Protein Co-Hitchhikes Interleukin-15 and Pheophorbide A for Cancer Photoimmunotherapy.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 615, doi. 10.3390/pharmaceutics17050615

By:

Li, Zhe;
Xu, Jiaojiao;
Lin, Hongzheng;
Yu, Sheng;
Sun, Jingwen;
Zhang, Chen;
Zhang, Sihang;
Li, Tingting;
Yang, Afeng;
Lu, Wei

Publication type:

Article

The ischaemia-modified albumin test: new tricks for an old dog?

Published in:

Biomarkers, 2025, v. 30, n. 3, p. 217, doi. 10.1080/1354750X.2025.2481407

By:

Wu, Alan H.B

Publication type:

Article

ADCs and TCE in SCLC Therapy: The Beginning of a New Era?

Published in:

Current Oncology, 2025, v. 32, n. 5, p. 261, doi. 10.3390/curroncol32050261

By:

Muscolino, Paola;
Omero, Fausto;
Speranza, Desirèe;
Infurna, Carla;
Parisi, Silvana;
Cianci, Vincenzo;
Berretta, Massimiliano;
Russo, Alessandro;
Santarpia, Mariacarmela

Publication type:

Article

From Good to Better: Comparative Epitope Profiling Facilitates Rational Design of Effective Multi‐Epitope Vaccines Against Viruses.

Published in:

Journal of Medical Virology, 2025, v. 97, n. 5, p. 1, doi. 10.1002/jmv.70366

By:

Li, Xinfeng;
Wang, Yiyao;
Zhong, Mingyue;
Liu, Lu;
Xue, Heng;
Chuai, Xia;
Wei, Hongping;
Chiu, Sandra;
Yang, Hang

Publication type:

Article

Co-targeting of epigenetic regulators and BCL-XL improves efficacy of immune checkpoint blockade therapy in multiple solid tumors.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02352-4

By:

Senent, Yaiza;
Fresquet, Vicente;
Jiménez, Victoria;
Valencia, Karmele;
Exposito, Francisco;
Martín-Úriz, Patxi San;
Camps, Gracián;
Fernández-Pierola, Eva;
de Córdoba, Borja Ruiz-Fernández;
González-Huarriz, Marisol;
Tamayo, Ibon;
Remírez, Ana;
Moreno, Haritz;
Serrano, Diego;
Ajona, Daniel;
Alonso, Marta M.;
Lecanda, Fernando;
Pineda-Lucena, Antonio;
Prósper, Felipe;
Sanmamed, Miguel F.

Publication type:

Article

Interferon regulatory factor-1–expressing astrocytes are epigenetically controlled and exacerbate TBI-associated pathology in mice.

Published in:

Science Translational Medicine, 2025, v. 17, n. 800, p. 1, doi. 10.1126/scitranslmed.adr5300

By:

Cui, Wenxing;
Bai, Hao;
Guo, Chengxuan;
Zhou, Jinpeng;
Feng, Dayun;
Zhang, Shiji;
Gao, Fei;
Han, Liying;
Tian, Yang;
Dong, Jingyu;
Wei, Feilong;
Bai, Jian;
Wu, Xun;
Shi, Yingwu;
Guo, Hao;
Wang, Liang;
Li, Zhihong;
Guo, Wei;
Zhao, Tianzhi;
Heng, Lijun

Publication type:

Article

Characteristics of human immunodeficiency virus-1 influencing the development and efficacy of anti-HIV-1 vaccines.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2024, v. 81, n. 12, p. 725, doi. 10.2298/VSP240812076B

By:

Božić, Dragana D.;
Ranin, Nevena Arsenović;
Jančić, Ivan;
Stanković, Jelena Antić;
Milenković, Marina T.;
Vasilev, Saša;
Bufan, Biljana

Publication type:

Article

Vitamin D and in vitro fertilization: a systematic review.

Published in:

Journal of Assisted Reproduction & Genetics, 2023, v. 40, n. 4, p. 735, doi. 10.1007/s10815-023-02767-2

By:

Eller, Ana Berquó Peleja;
Ejzenberg, Dani;
Monteleone, Pedro Augusto Araújo;
Soares Jr., José Maria;
Baracat, Edmund Chada

Publication type:

Article

Effects of long term low dose acrylamide exposure on rat bone marrow polychromatic erythrocytes.

Published in:

Biotechnic & Histochemistry, 2013, v. 88, n. 6, p. 356, doi. 10.3109/10520295.2013.790561

By:

Yener, Y

Publication type:

Article

Regulation of programmed death ligand 1 expression by interferon‐γ and tumour necrosis factor‐α in canine tumour cell lines.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 2, p. 279, doi. 10.1111/vco.12886

By:

Owaki, Ryo;
Deguchi, Tatsuya;
Konnai, Satoru;
Maekawa, Naoya;
Okagawa, Tomohiro;
Hosoya, Kenji;
Kim, Sangho;
Sunaga, Takafumi;
Okumura, Masahiro

Publication type:

Article

Local tumour nanoparticle thermal therapy: A promising immunomodulatory treatment for canine cancer.

Published in:

Veterinary & Comparative Oncology, 2022, v. 20, n. 4, p. 752, doi. 10.1111/vco.12842

By:

Castelló, Carla Martí;
de Carvalho, Mara Taís;
Bakuzis, Andris Figueiroa;
Fonseca, Simone Gonçalves;
Miguel, Marina Pacheco

Publication type:

Article

Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B‐cell lymphoma.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 4, p. 739, doi. 10.1111/vco.12602

By:

Sakai, Osamu;
Igase, Masaya;
Mizuno, Takuya

Publication type:

Article

Tumour‐infiltrating lymphocytes in canine melanocytic tumours: An investigation on the prognostic role of CD3+ and CD20+ lymphocytic populations.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 3, p. 370, doi. 10.1111/vco.12556

By:

Porcellato, Ilaria;
Silvestri, Serenella;
Menchetti, Laura;
Recupero, Francesca;
Mechelli, Luca;
Sforna, Monica;
Iussich, Selina;
Bongiovanni, Laura;
Lepri, Elvio;
Brachelente, Chiara

Publication type:

Article

Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 20, p. 4476, doi. 10.1002/chem.201905279

By:

Hartrampf, Nina;
Seki, Toshiyuki;
Baumann, Andreas;
Watson, Philip;
Vepřek, Nynke A.;
Hetzler, Belinda E.;
Hoffmann‐Röder, Anja;
Tsuji, Moriya;
Trauner, Dirk

Publication type:

Article

Investigation the immunotherapeutic potential of miR-4477a targeting PD-1/PD-L1 in breast cancer cell line using a CD8+ co-culture model.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10435-0

By:

Tülüce, Yasin;
Köstekci, Sedat;
Karakuş, Fuat;
Keleş, Ahmet Yasin;
Tunçyürekli, Merve

Publication type:

Article

Ruthenium (II) polypyridyl complexes stabilize the bcl-2 promoter quadruplex and induce apoptosis of Hela tumor cells.

Published in:

BioMetals, 2013, v. 26, n. 3, p. 387, doi. 10.1007/s10534-013-9622-6

By:

Wang, Chuan;
Yu, Qianqian;
Yang, Licong;
Liu, Yanyu;
Sun, Dongdong;
Huang, Yongchao;
Zhou, Yanhui;
Zhang, Qianling;
Liu, Jie

Publication type:

Article

Mechanisms of melanocyte death in vitiligo.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 2, p. 1138, doi. 10.1002/med.21754

By:

Chen, Jianru;
Li, Shuli;
Li, Chunying

Publication type:

Article

Reinvigorating exhausted CD8+ cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 1, p. 156, doi. 10.1002/med.21727

By:

Hossain, Md Amir;
Liu, Guilai;
Dai, Beiying;
Si, Yaxuan;
Yang, Qitao;
Wazir, Junaid;
Birnbaumer, Lutz;
Yang, Yong

Publication type:

Article

Stable and transient periodic oscillations in a mathematical model for CTL response to HTLV-I infection.

Published in:

Journal of Mathematical Biology, 2012, v. 65, n. 1, p. 181, doi. 10.1007/s00285-011-0455-z

By:

Lang, John;
Li, Michael

Publication type:

Article

SARS-Cov-2 fulminant myocarditis: an autopsy and histopathological case study.

Published in:

International Journal of Legal Medicine, 2021, v. 135, n. 2, p. 577, doi. 10.1007/s00414-020-02500-z

By:

Gauchotte, Guillaume;
Venard, Véronique;
Segondy, Michaël;
Cadoz, Cyril;
Esposito-Fava, Aude;
Barraud, Damien;
Louis, Guillaume

Publication type:

Article

Harnessing IL-27: challenges and potential in cancer immunotherapy.

Published in:

2025

By:

Maleki, Ali Heidarnejad;
Rajabivahid, Mansour;
Khosh, Elnaz;
Khanali, Zeinab;
Tahmasebi, Safa;
Ghorbi, Mahmood Dehghani

Publication type:

Literature Review

Isoleucine/leucine residues at 'a' and 'd' positions of a heptad repeat sequence are crucial for the cytolytic activity of a short anticancer lytic peptide.

Published in:

Amino Acids, 2017, v. 49, n. 1, p. 193, doi. 10.1007/s00726-016-2350-9

By:

Fan, Ruru;
Yuan, Yanyan;
Zhang, Qiang;
Zhou, Xi-Rui;
Jia, Lili;
Liu, Zhuqing;
Yu, Changyuan;
Luo, Shi-Zhong;
Chen, Long

Publication type:

Article

Modulation of Immune Cell Subsets by Hepatitis C Virus and Antiviral Therapy in Early Virological Response HCV Genotype 4-Infected Patients with Compensated Liver Disease.

Published in:

2021

By:

Essa, Sahar;
Al-Attiyah, Raja'a;
Siddique, Iqbal;
Al-Nakib, Widad

Publication type:

journal article

LAG3 and TIGIT Expression on Tumor-Infiltrating Lymphocytes in Cutaneous Melanoma.

Published in:

Dermatology (10188665), 2024, v. 240, n. 1, p. 156, doi. 10.1159/000533932

By:

Naimy, Soraya;
Bzorek, Michael;
Eriksen, Jens Ole;
Løvendorf, Marianne Bengtson;
Litman, Thomas;
Dyring-Andersen, Beatrice;
Gjerdrum, Lise Mette Rahbek

Publication type:

Article

Proteolysis of tau by granzyme A in tauopathies generates fragments that are aggregation prone.

Published in:

Biochemical Journal, 2024, v. 481, n. 18, p. 1255, doi. 10.1042/BCJ20240007

By:

Quinn, James P.;
Fisher, Kate;
Corbett, Nicola;
Warwood, Stacey;
Knight, David;
Kellett, Katherine A. B.;
Hooper, Nigel M.

Publication type:

Article

Regulation of Tim-3 function by binding to phosphatidylserine.

Published in:

Biochemical Journal, 2021, v. 478, n. 22, p. 3999, doi. 10.1042/BCJ20210652

By:

Kane, Lawrence P.

Publication type:

Article

Defining the clonality of peripheral T cell lymphomas using RNA-seq.

Published in:

Bioinformatics, 2017, v. 33, n. 8, p. 1111, doi. 10.1093/bioinformatics/btw810

By:

Brown, Scott D.;
Hapgood, Greg;
Steidl, Christian;
Weng, Andrew P.;
Savage, Kerry J.;
Holt, Robert A.

Publication type:

Article

Investigation of Immunostimulatory Effects of IFN‐γ Cytokine and CD40 Ligand Costimulatory Molecule for Development of HIV‐1 Therapeutic Vaccine Candidate.

Published in:

Advanced Biology, 2024, v. 8, n. 2, p. 1, doi. 10.1002/adbi.202300402

By:

Heidarnejad, Fatemeh;
Bolhassani, Azam;
Ajdary, Soheila;
Milani, Alireza;
Sadeghi, Seyed Amir

Publication type:

Article

CD4+ Cytotoxic T Lymphocytes in Cancer Immunity and Immunotherapy.

Published in:

Advanced Biology, 2023, v. 7, n. 4, p. 1, doi. 10.1002/adbi.202200169

By:

Wang, Boyu;
Hu, Shaojie;
Fu, Xiangning;
Li, Lequn

Publication type:

Article

Sensory Neurotransmitter Calcitonin Gene‐Related Peptide Modulates Tumor Growth and Lymphocyte Infiltration in Oral Squamous Cell Carcinoma.

Published in:

Advanced Biology, 2022, v. 6, n. 9, p. 1, doi. 10.1002/adbi.202200019

By:

McIlvried, Lisa A.;
Atherton, Megan A.;
Horan, Nicole L.;
Goch, Tori N.;
Scheff, Nicole N.

Publication type:

Article

Disulfidptosis: a novel gene-based signature predicts prognosis and immunotherapy efficacy of pancreatic adenocarcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02053-w

By:

Yin, Jingyang;
Li, Jian;
Wang, Huaizhi

Publication type:

Article

Development of a novel prognostic signature based on cytotoxic T lymphocyte-evasion genes for hepatocellular carcinoma patient management.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01909-5

By:

Zhu, Qinmei;
Liao, Shiping;
Wei, Ting;
Liu, Suya;
Yang, Chunqian;
Tang, Jingsong

Publication type:

Article

Cancer phenomics research hotspots and development trends: a bibliometric analysis from 2000 to 2023.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01710-w

By:

Chen, Shupeng;
Liu, Jie;
Tang, Nana;
Zeng, Yingjian

Publication type:

Article

FCGBP functions as a tumor suppressor gene in head and neck squamous cell carcinoma.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01607-8

By:

Zeng, Lijuan;
Zeng, Jun;
He, Jianfeng;
Li, Yongqi;
Li, Chengwei;
Lin, Zhiyan;
Chen, Guangwei;
Wu, Huilin;
Zhou, Libin

Publication type:

Article

Natural killer (NK) cells-related gene signature reveals the immune environment heterogeneity in hepatocellular carcinoma based on single cell analysis.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01287-4

By:

Ye, Zhirong;
Li, Wenjun;
Ouyang, Hao;
Ruan, Zikang;
Liu, Xun;
Lin, Xiaoxia;
Chen, Xuanting

Publication type:

Article