Title: The dose distribution in dominant intraprostatic tumour lesions defined by multiparametric MRI and PSMA PET/CT correlates with the outcome in patients treated with primary radiation therapy for prostate cancer.
Authors: Zamboglou, Constantinos; Klein, Christina Marie; Thomann, Benedikt; Fassbender, Thomas Franz; Rischke, Hans C.; Kirste, Simon; Henne, Karl; Volegova-Neher, Natalja; Bock, Michael; Langer, Mathias; Meyer, Philipp T.; Baltas, Dimos; Grosu, Anca L.
Abstract: The article presents research demonstrating the correlation of intraprostatic tumour lesion dominant dose distribution with the radio therapy of prostate cancer patients. The study shows the possible depicture of dominant intraprostatic lesions by multimodal imaging techniques, the potential impact of radiotherapy distribution on patient outcome, and the dose parameters of the therapy.
Subjects: PROSTATE cancer treatment; PROSTATE cancer prevention; RADIOTHERAPY; MAGNETIC resonance imaging; HEALTH outcome assessment; DIAGNOSTIC imaging; COMPUTERS in medicine; PROSTATE tumors; RADIATION doses; PROPORTIONAL hazards models; RETROSPECTIVE studies; KAPLAN-Meier estimator
Publication: Radiation Oncology, 2018, Vol 13, Issue 1, pN.PAG
ISSN: 1748-717X
Publication type: Academic Journal
DOI: 10.1186/s13014-018-1014-1

The dose distribution in dominant intraprostatic tumour lesions defined by multiparametric MRI and PSMA PET/CT correlates with the outcome in patients treated with primary radiation therapy for prostate cancer.

Zamboglou, Constantinos; Klein, Christina Marie; Thomann, Benedikt; Fassbender, Thomas Franz; Rischke, Hans C.; Kirste, Simon; Henne, Karl; Volegova-Neher, Natalja; Bock, Michael; Langer, Mathias; Meyer, Philipp T.; Baltas, Dimos; Grosu, Anca L.