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- Title
Evidence for communication of peripheral iron status to cerebrospinal fluid: clinical implications for therapeutic strategy.
- Authors
Connor, James R; Duck, Kari; Patton, Stephanie; Simpson, Ian A; Trotti, Lynn Marie; Allen, Richard; Earley, Christopher J; Rye, David
- Abstract
Iron is crucial for proper functioning of all organs including the brain. Deficiencies and excess of iron are common and contribute to substantial morbidity and mortality. Whereas iron's involvement in erythropoiesis drives clinical practice, the guidelines informing interventional strategies for iron repletion in neurological disorders are poorly defined. The objective of this study was to determine if peripheral iron status is communicated to the brain.
- Publication
Fluids and barriers of the CNS, 2020, Vol 17, Issue 1, p28
- ISSN
2045-8118
- Publication type
Journal Article
- DOI
10.1186/s12987-020-00190-8