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Principles for designing future regimens for multidrug-resistant tuberculosis.
Published in:
Bulletin of the World Health Organization, 2014, v. 92, n. 1, p. 68, doi. 10.2471/BLT.13.122028
By:
- Brigden, Grania;
- Nyang'wa, Bern-Thomas;
- du Cros, Philipp;
- Varaine, Francis;
- Hughes, Jennifer;
- Rich, Michael;
- Horsburgh Jr, C. Robert;
- Mitnick, Carole D.;
- Nuermberger, Eric;
- McIlleron, Helen;
- Phillips, Patrick P. J.;
- Balasegaram, Manica
Publication type:
Article
A flexible multi‐metric Bayesian framework for decision‐making in Phase II multi‐arm multi‐stage studies.
Published in:
Statistics in Medicine, 2024, v. 43, n. 3, p. 501, doi. 10.1002/sim.9961
By:
- Dufault, Suzanne M.;
- Crook, Angela M.;
- Rolfe, Katie;
- Phillips, Patrick P. J.
Publication type:
Article
The evolution of and challenges in defining the clinical endpoint in tuberculosis treatment trials with non-inferiority designs.
Published in:
2011
By:
- Phillips, Patrick P. J.;
- Crook, Angela;
- Nunn, Andrew J.
Publication type:
Abstract
A Standardized Approach for Collection of Objective Data to Support Outcome Determination for Late-Phase Tuberculosis Clinical Trials.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 10, p. 1376, doi. 10.1164/rccm.202206-1118OC
By:
- Kurbatova, Ekaterina V.;
- Phillips, Patrick P. J.;
- Dorman, Susan E.;
- Sizemore, Erin E.;
- Bryant, Kia E.;
- Purfield, Anne E.;
- Ricaldi, Jessica;
- Brown, Nicole E.;
- Johnson, John L.;
- Wallis, Carole L.;
- Akol, Joseph P.;
- Ocheretina, Oksana;
- Nguyen Van Hung;
- Mayanja-Kizza, Harriet;
- Lourens, Madeleine;
- Dawson, Rodney;
- Nguyen Viet Nhung;
- Pierre, Samuel;
- Musodza, Yeukai;
- Shenje, Justin
Publication type:
Article
To Err Is Human, to Forgive Is Pharmacodynamic.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 2, p. 127, doi. 10.1164/rccm.202208-1629ED
By:
- Phillips, Patrick P. J.;
- Stout, Jason E.
Publication type:
Article
Precision-Enhancing Risk Stratification Tools for Selecting Optimal Treatment Durations in Tuberculosis Clinical Trials.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2021, v. 204, n. 9, p. 1086, doi. 10.1164/rccm.202101-0117OC
By:
- Imperial, Marjorie Z.;
- Phillips, Patrick P. J.;
- Nahid, Payam;
- Savic, Radojka M.
Publication type:
Article
Reply to Swindells : Trials of Tuberculosis-Preventive Therapy in People with HIV Infection.
Published in:
2020
By:
- Stout, Jason E;
- Turner, Nicholas A;
- Belknap, Robert W;
- Horsburgh, C Robert;
- Sterling, Timothy R;
- Phillips, Patrick P J
Publication type:
letter
Reply to Swindells et al.
Published in:
2020
By:
- Stout, Jason E.;
- Turner, Nicholas A.;
- Belknap, Robert W.;
- Horsburgh, C. Robert;
- Sterling, Timothy R.;
- Phillips, Patrick P. J.
Publication type:
Letter to the Editor
Optimizing the Design of Latent Tuberculosis Treatment Trials: Insights from Mathematical Modeling.
Published in:
2020
By:
- Stout, Jason E.;
- Turner, Nicholas A.;
- Belknap, Robert W.;
- Horsburgh, C. Robert;
- Sterling, Timothy R.;
- Phillips, Patrick P. J.
Publication type:
journal article
Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status.
Published in:
2019
By:
- Tweed, Conor D.;
- Crook, Angela M.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- McHugh, Timothy D.;
- Mendel, Carl M.;
- Meredith, Sarah K.;
- Mohapi, Lerato;
- Murphy, Michael E.;
- Nunn, Andrew J.;
- Phillips, Patrick P. J.;
- Singh, Kasha P.;
- Spigelman, Melvin;
- Gillespie, Stephen H.
Publication type:
journal article
A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP).
Published in:
2016
By:
- Phillips, Patrick P. J.;
- Dooley, Kelly E.;
- Gillespie, Stephen H.;
- Heinrich, Norbert;
- Stout, Jason E.;
- Nahid, Payam;
- Diacon, Andreas H.;
- Aarnoutse, Rob E.;
- Kibiki, Gibson S.;
- Boeree, Martin J.;
- Hoelscher, Michael
Publication type:
journal article
World TB Day 2016: an interview with leading experts in tuberculosis research.
Published in:
2016
By:
- Phillips, Patrick P. J.;
- Fletcher, Helen A.;
- Abubakar, Ibrahim;
- Lipman, Marc C. I.;
- McHugh, Timothy D.
Publication type:
editorial
Erratum to: Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials.
Published in:
2016
By:
- Phillips, Patrick P J;
- Mendel, Carl M;
- Burger, Divan A;
- Crook, Angela M;
- Nunn, Andrew J;
- Dawson, Rodney;
- Diacon, Andreas H;
- Gillespie, Stephen H
Publication type:
corrected article
Limited role of culture conversion for decision-making in individual patient care and for advancing novel regimens to confirmatory clinical trials.
Published in:
2016
By:
- Phillips, Patrick P. J.;
- Mendel, Carl M.;
- Burger, Divan A.;
- Crook, Angela;
- Nunn, Andrew J.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- Gillespie, Stephen H.;
- Crook, Angela M
Publication type:
journal article
Validation of a Handheld 6-Lead Device for QT Interval Monitoring in Resource-Limited Settings.
Published in:
JAMA Network Open, 2024, v. 7, n. 6, p. e2415576, doi. 10.1001/jamanetworkopen.2024.15576
By:
- Metcalfe, John Z.;
- Economou, Tamsin;
- Naufal, Fahd;
- Kucukosmanoglu, Murat;
- Kleiman, Robert;
- Phillips, Patrick P. J.;
- Conradie, Francesca
Publication type:
Article
Protocol for a feasibility randomized controlled trial to evaluate the efficacy, safety and tolerability of N-acetylcysteine in reducing adverse drug reactions among adults treated for multidrug-resistant tuberculosis in Tanzania.
Published in:
Pilot & Feasibility Studies, 2023, v. 9, n. 1, p. 1, doi. 10.1186/s40814-023-01281-7
By:
- Mpagama, Stellah G.;
- Mvungi, Happiness C.;
- Mbelele, Peter M.;
- Semvua, Hadija H.;
- Liyoyo, Alphonce A.;
- de Guex, Kristen Petros;
- Sloan, Derek;
- Kibiki, Gibson S.;
- Boeree, Martin;
- Phillips, Patrick P. J.;
- Heysell, Scott K.
Publication type:
Article
Reply to Dodd and Proschan.
Published in:
2013
By:
- Phillips, Patrick P. J.;
- Bratton, Daniel J.;
- Nunn, Andrew J.;
- Hoelscher, Michael
Publication type:
Letter
Innovative Trial Designs Are Practical Solutions for Improving the Treatment of Tuberculosis.
Published in:
Journal of Infectious Diseases, 2012, v. 205, n. suppl_2, p. S250, doi. 10.1093/infdis/jis041
By:
- Phillips, Patrick P. J.;
- Gillespie, Stephen H.;
- Boeree, Martin;
- Heinrich, Norbert;
- Aarnoutse, Rob;
- McHugh, Tim;
- Pletschette, Michel;
- Lienhardt, Christian;
- Hafner, Richard;
- Mgone, Charles;
- Zumla, Alimuddin;
- Nunn, Andrew J.;
- Hoelscher, Michael
Publication type:
Article
Innovative trial designs are practical solutions for improving the treatment of tuberculosis.
Published in:
2012
By:
- Phillips, Patrick P J;
- Gillespie, Stephen H;
- Boeree, Martin;
- Heinrich, Norbert;
- Aarnoutse, Rob;
- McHugh, Tim;
- Pletschette, Michel;
- Lienhardt, Christian;
- Hafner, Richard;
- Mgone, Charles;
- Zumla, Alimuddin;
- Nunn, Andrew J;
- Hoelscher, Michael
Publication type:
journal article
Biomarkers and Surrogate End Points in Clinical Trials of Tuberculosis Treatment.
Published in:
2007
By:
- Davies, Geraint Rhys;
- Phillips, Patrick P. J.;
- Nunn, Andrew J.
Publication type:
Letter
Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape.
Published in:
2019
By:
- Phillips, Patrick P. J.;
- Mitnick, Carole D.;
- Neaton, James D.;
- Nahid, Payam;
- Lienhardt, Christian;
- Nunn, Andrew J.
Publication type:
journal article
Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 5, p. 1558, doi. 10.1093/jac/dku553
By:
- Heinrich, Norbert;
- Dawson, Rodney;
- du Bois, Jeannine;
- Narunsky, Kim;
- Horwith, Gary;
- Phipps, Andrew J.;
- Nacy, Carol A.;
- Aarnoutse, Rob E.;
- Boeree, Martin J.;
- Gillespie, Stephen H.;
- Venter, Amour;
- Henne, Sonja;
- Rachow, Andrea;
- Phillips, Patrick P. J.;
- Hoelscher, Michael;
- Diacon, Andreas H.
Publication type:
Article
The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially reflecting the impact of chemotherapy on critical sub-populations.
Published in:
2015
By:
- Bowness, Ruth;
- Boeree, Martin J;
- Aarnoutse, Rob;
- Dawson, Rodney;
- Diacon, Andreas;
- Mangu, Chacha;
- Heinrich, Norbert;
- Ntinginya, Nyanda E;
- Kohlenberg, Anke;
- Mtafya, Bariki;
- Phillips, Patrick P J;
- Rachow, Andrea;
- Plemper van Balen, Georgette;
- Gillespie, Stephen H
Publication type:
journal article
Rifapentine With and Without Moxifloxacin for Pulmonary Tuberculosis in People With Human Immunodeficiency Virus (S31/A5349).
Published in:
Clinical Infectious Diseases, 2023, v. 76, n. 3, p. e580, doi. 10.1093/cid/ciac707
By:
- Pettit, April C;
- Phillips, Patrick P J;
- Kurbatova, Ekaterina;
- Vernon, Andrew;
- Nahid, Payam;
- Dawson, Rodney;
- Dooley, Kelly E;
- Sanne, Ian;
- Waja, Ziyaad;
- Mohapi, Lerato;
- Podany, Anthony T;
- Samaneka, Wadzanai;
- Savic, Rada M;
- Johnson, John L;
- Muzanyi, Grace;
- Lalloo, Umesh G;
- Bryant, Kia;
- Sizemore, Erin;
- Scott, Nigel;
- Dorman, Susan E
Publication type:
Article
Efavirenz Pharmacokinetics and Human Immunodeficiency Virus Type 1 (HIV-1) Viral Suppression Among Patients Receiving Tuberculosis Treatment Containing Daily High-Dose Rifapentine.
Published in:
Clinical Infectious Diseases, 2022, v. 75, n. 4, p. 560, doi. 10.1093/cid/ciab1037
By:
- Podany, Anthony T;
- Pham, Michelle;
- Sizemore, Erin;
- Martinson, Neil;
- Samaneka, Wadzanai;
- Mohapi, Lerato;
- Badal-Faesen, Sharlaa;
- Dawson, Rod;
- Johnson, John L;
- Mayanja, Harriet;
- Lalloo, Umesh;
- Whitworth, William C;
- Pettit, April;
- Campbell, Kayla;
- Phillips, Patrick P J;
- Bryant, Kia;
- Scott, Nigel;
- Vernon, Andrew;
- Kurbatova, Ekaterina V;
- Chaisson, Richard E
Publication type:
Article
Type I error rates of multi-arm multi-stage clinical trials: strong control and impact of intermediate outcomes.
Published in:
2016
By:
- Bratton, Daniel J.;
- Parmar, Mahesh K. B.;
- Phillips, Patrick P. J.;
- Choodari-Oskooei, Babak
Publication type:
journal article
Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial.
Published in:
Trials, 2014, v. 15, n. 1, p. 353, doi. 10.1186/1745-6215-15-353
By:
- Nunn, Andrew J.;
- Rusen, I. D.;
- Van Deun, Armand;
- Torrea, Gabriela;
- Phillips, Patrick P. J.;
- Chen-Yuan Chiang;
- Squire, S. Bertel;
- Madan, Jason;
- Meredith, Sarah K.
Publication type:
Article
Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial.
Published in:
2014
By:
- Nunn, Andrew J;
- Rusen, Id;
- Van Deun, Armand;
- Torrea, Gabriela;
- Phillips, Patrick Pj;
- Chiang, Chen-Yuan;
- Squire, S Bertel;
- Madan, Jason;
- Meredith, Sarah K;
- Rusen, I D;
- Phillips, Patrick P J
Publication type:
journal article
A Step toward an Optimized Rifampin Dose Completed.
Published in:
2015
By:
- Boeree, Martin J;
- Diacon, Andreas H;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P J;
- Gillespie, Stephen H;
- McHugh, Timothy D;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- Plemper van Balen, Georgette;
- Aarnoutse, Rob E
Publication type:
letter
A Step toward an Optimized Rifampin Dose Completed.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 4, p. 525, doi. 10.1164/rccm.201506-1061le
By:
- Boeree, Martin J.;
- Diacon, Andreas H.;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P. J.;
- Gillespie, Stephen H.;
- McHugh, Timothy D.;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- van Balen, Georgette Plemper;
- Aarnoutse, Rob E.
Publication type:
Article
A Dose-Ranging Trial to Optimize the Dose of Rifampin in the Treatment of Tuberculosis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 9, p. 1058, doi. 10.1164/rccm.201407-1264OC
By:
- Boeree, Martin J.;
- Diacon, Andreas H.;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P. J.;
- Gillespie, Stephen H.;
- McHugh, Timothy D.;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- van Balen, Georgette Plemper;
- Aarnoutse, Rob E.
Publication type:
Article
A dose escalating trial to optimize the dose of rifampin in the treatment of tuberculosis.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2015, v. 191, n. 9, p. E1, doi. 10.1164/rccm.201407-1264oc
By:
- Boeree, Martin J.;
- Diacon, Andreas H.;
- Dawson, Rodney;
- Narunsky, Kim;
- du Bois, Jeannine;
- Venter, Amour;
- Phillips, Patrick P. J.;
- Gillespie, Stephen H.;
- Mc Hugh, Timothy D.;
- Hoelscher, Michael;
- Heinrich, Norbert;
- Rehal, Sunita;
- van Soolingen, Dick;
- van Ingen, Jakko;
- Magis-Escurra, Cecile;
- Burger, David;
- van Balen, Georgette Plemper;
- Aarnoutse, Rob E.
Publication type:
Article
Tuberculosis Biomarker and Surrogate Endpoint Research Roadmap.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2011, v. 184, n. 8, p. 972, doi. 10.1164/rccm.201105-0827WS
By:
- Nahid, Payam;
- Saukkonen, Jussi;
- Kenzie, William R. Mac;
- Johnson, John L.;
- Phillips, Patrick P. J.;
- Andersen, Janet;
- Bliven-Sizemore, Erin;
- Belisle, John T.;
- Boom, W. Henry;
- Luetkemeyer, Annie;
- Campbell, Thomas B.;
- Eisenach, Kathleen D.;
- Hafner, Richard;
- Lennox, Jeffrey L.;
- Makhene, Mamodikoe;
- Swindells, Susan;
- Villarino, M. Elsa;
- Weiner, Marc;
- Benson, Constance;
- Burman, William
Publication type:
Article
A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis.
Published in:
BMC Medical Research Methodology, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2288-13-139
By:
- Bratton, Daniel J.;
- Phillips, Patrick P. J.;
- Parmar, Mahesh K. B.
Publication type:
Article
A multi-arm multi-stage clinical trial design for binary outcomes with application to tuberculosis.
Published in:
2013
By:
- Bratton, Daniel J;
- Phillips, Patrick Pj;
- Parmar, Mahesh Kb;
- Phillips, Patrick P J;
- Parmar, Mahesh K B
Publication type:
journal article
Rethinking non-inferiority: a practical trial design for optimising treatment duration.
Published in:
Clinical Trials, 2018, v. 15, n. 5, p. 477, doi. 10.1177/1740774518778027
By:
- Quartagno, Matteo;
- Walker, A. Sarah;
- Carpenter, James R.;
- Phillips, Patrick P. J.;
- Parmar, Mahesh KB
Publication type:
Article
Testing many treatments within a single protocol over 10 years at MRC Clinical Trials Unit at UCL: Multi-arm, multi-stage platform, umbrella and basket protocols.
Published in:
Clinical Trials, 2017, v. 14, n. 5, p. 451, doi. 10.1177/1740774517725697
By:
- Parmar, Mahesh K. B.;
- Sydes, Matthew R.;
- Cafferty, Fay H.;
- Choodari-Oskooei, Babak;
- Langley, Ruth E.;
- Brown, Louise;
- Phillips, Patrick P. J.;
- Spears, Melissa R.;
- Rowley, Sam;
- Kaplan, Richard;
- James, Nicholas D.;
- Maughan, Timothy;
- Paton, Nicholas;
- Royston, Patrick J.
Publication type:
Article
An Evaluation of Culture Results during Treatment for Tuberculosis as Surrogate Endpoints for Treatment Failure and Relapse
Published in:
PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063840
By:
- Phillips, Patrick P. J.;
- Fielding, Katherine;
- Nunn, Andrew J.
Publication type:
Article
Estimands for clinical endpoints in tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial.
Published in:
Trials, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13063-024-07999-w
By:
- Weir, Isabelle R.;
- Dufault, Suzanne M.;
- Phillips, Patrick P. J.
Publication type:
Article
Protocol for the 3HP Options Trial: a hybrid type 3 implementation-effectiveness randomized trial of delivery strategies for short-course tuberculosis preventive therapy among people living with HIV in Uganda.
Published in:
2020
By:
- Kadota, Jillian L.;
- Musinguzi, Allan;
- Nabunje, Juliet;
- Welishe, Fred;
- Ssemata, Jackie L.;
- Bishop, Opira;
- Berger, Christopher A.;
- Patel, Devika;
- Sammann, Amanda;
- Katahoire, Anne;
- Nahid, Payam;
- Belknap, Robert;
- Phillips, Patrick P. J.;
- Namusobya, Jennifer;
- Kamya, Moses;
- Handley, Margaret A.;
- Kiwanuka, Noah;
- Katamba, Achilles;
- Dowdy, David;
- Semitala, Fred C.
Publication type:
journal article
Comments on 'A modest proposal for dropping poor arms in clinical trials' by Proschan and Dodd.
Published in:
Statistics in Medicine, 2015, v. 34, n. 18, p. 2678, doi. 10.1002/sim.6337
By:
- Bratton, Daniel J.;
- Choodari ‐ Oskooei, Babak;
- Phillips, Patrick P. J.;
- Sydes, Matthew R.;
- Parmar, Mahesh K. B.
Publication type:
Article
Treatment-shortening regimens for tuberculosis: updates and future priorities.
Published in:
Breathe, 2023, v. 19, n. 3, p. 1, doi. 10.1183/20734735.0028-2023
By:
- Saluzzo, Francesca;
- Abiola Adepoju, Victor;
- Duarte, Raquel;
- Lange, Christoph;
- Phillips, Patrick P. J.
Publication type:
Article
Setting Tuberculosis Regimen Development on a Firm Foundation.
Published in:
2017
By:
- Phillips, Patrick P. J.
Publication type:
Editorial
An Analysis With Serious Flaws.
Published in:
2013
By:
- Nunn, Andrew J.;
- Phillips, Patrick P. J.
Publication type:
Letter
Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
Published in:
2018
By:
- Tweed, Conor Duncan;
- Wills, Genevieve Helen;
- Crook, Angela M.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- Louw, Cheryl E.;
- McHugh, Timothy D.;
- Mendel, Carl;
- Meredith, Sarah;
- Mohapi, Lerato;
- Murphy, Michael E.;
- Murray, Stephen;
- Murthy, Sara;
- Nunn, Andrew J.;
- Phillips, Patrick P. J.;
- Singh, Kasha;
- Spigelman, M.;
- Gillespie, S. H.
Publication type:
journal article
Toxicity associated with tuberculosis chemotherapy in the REMoxTB study.
Published in:
2018
By:
- Tweed, Conor D.;
- Crook, Angela M.;
- Amukoye, Evans I.;
- Dawson, Rodney;
- Diacon, Andreas H.;
- Hanekom, Madeline;
- McHugh, Timothy D.;
- Mendel, Carl M.;
- Meredith, Sarah K.;
- Murphy, Michael E.;
- Murthy, Saraswathi E.;
- Nunn, Andrew J.;
- Phillips, Patrick P. J.;
- Singh, Kasha P.;
- Spigelman, Melvin;
- Wills, Genevieve H.;
- Gillespie, Stephen H.
Publication type:
journal article
Tuberculosis screening improves preventive therapy uptake (TB SCRIPT) trial among people living with HIV in Uganda: a study protocol of an individual randomized controlled trial.
Published in:
2022
By:
- Semitala, Fred C.;
- Chaisson, Lelia H.;
- Dowdy, David W.;
- Armstrong, Derek T.;
- Opira, Bishop;
- Aman, Kyomugisha;
- Kamya, Moses;
- Phillips, Patrick P. J.;
- Yoon, Christina
Publication type:
journal article
A comparison of liquid and solid culture for determining relapse and durable cure in phase III TB trials for new regimens.
Published in:
2017
By:
- Phillips, Patrick P. J.;
- Mendel, Carl M.;
- Nunn, Andrew J.;
- McHugh, Timothy D.;
- Crook, Angela M.;
- Hunt, Robert;
- Bateson, Anna;
- Gillespie, Stephen H.
Publication type:
journal article
Spot sputum samples are at least as good as early morning samples for identifying Mycobacterium tuberculosis.
Published in:
2017
By:
- Murphy, Michael E.;
- Phillips, Patrick P. J.;
- Mendel, Carl M.;
- Bongard, Emily;
- Bateson, Anna L. C.;
- Hunt, Robert;
- Murthy, Saraswathi;
- Singh, Kasha P.;
- Brown, Michael;
- Crook, Angela M.;
- Nunn, Andrew J.;
- Meredith, Sarah K.;
- Lipman, Marc;
- McHugh, Timothy D.;
- Gillespie, Stephen H.;
- REMoxTB Consortium
Publication type:
journal article
Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial.
Published in:
2017
By:
- Witney, Adam A.;
- Bateson, Anna L. E.;
- Jindani, Amina;
- Phillips, Patrick P. J.;
- Coleman, David;
- Stoker, Neil G.;
- Butcher, Philip D.;
- McHugh, Timothy D.;
- RIFAQUIN Study Team
Publication type:
journal article

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