Works matching DE "PHARMACEUTICAL chemistry"

Results: 5000

Multitarget Design of Steroidal Inhibitors Against Hormone-Dependent Breast Cancer: An Integrated In Silico Approach.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7477, doi. 10.3390/ijms26157477

By:

Rodríguez-Macías, Juan;
Saurith-Coronell, Oscar;
Vargas-Echeverria, Carlos;
Delgado, Daniel Insuasty;
Márquez Brazón, Edgar A.;
De Aguas, Ricardo Gutiérrez;
Mora, José R.;
Paz, José L.;
Marrero-Ponce, Yovanni

Publication type:

Article

Aspirin Eugenol Ester Ameliorates HFD-Induced NAFLD in Mice via the Modulation of Bile Acid Metabolism.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 15, p. 7044, doi. 10.3390/ijms26157044

By:

Zhang, Zhi-Jie;
Tao, Qi;
Feng, Ji;
Yu, Qin-Fang;
Fan, Li-Ping;
Wang, Zi-Hao;
Ge, Wen-Bo;
Li, Jian-Yong;
Yang, Ya-Jun

Publication type:

Article

Flavonoid Extract of Senecio scandens Buch.-Ham. Ameliorates CTX-Induced Immunosuppression and Intestinal Damage via Activating the MyD88-Mediated Nuclear Factor-κB Signaling Pathway.

Published in:

Nutrients, 2025, v. 17, n. 15, p. 2540, doi. 10.3390/nu17152540

By:

Zhu, Xiaolin;
Zhang, Lulu;
Ni, Xuan;
Guo, Jian;
Fang, Yizhuo;
Xu, Jianghan;
Chen, Zhuo;
Hao, Zhihui

Publication type:

Article

Flavone C-Glycosides from Dianthus superbus L. Attenuate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) via Multi-Pathway Regulations.

Published in:

Nutrients, 2025, v. 17, n. 15, p. 2456, doi. 10.3390/nu17152456

By:

Chu, Ming;
Tong, Yingying;
Zhang, Lei;
Zhang, Yu;
Dang, Jun;
Li, Gang

Publication type:

Article

Trans-Sodium Crocetinate Ameliorates High-Altitude Acute Lung Injury via Modulating EGFR/PI3K/AKT/NF-κB Signaling Axis.

Published in:

Nutrients, 2025, v. 17, n. 15, p. 2406, doi. 10.3390/nu17152406

By:

Liang, Keke;
Ta, Yanlin;
Xu, Liang;
Ma, Shuhe;
Wang, Renjie;
Xiao, Chenrong;
Gao, Yue;
Li, Maoxing

Publication type:

Article

Emodin promotes GSK-3β-mediated PD-L1 proteasomal degradation and enhances anti-tumor immunity in hepatocellular carcinoma.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01146-6

By:

Yang, Xuemei;
Chen, Weiguang;
Sun, Haitao;
Chen, Weicong;
Xu, Wei;
He, Chunyu;
Liu, Yang;
Kuang, Ying;
Ma, Yanhao;
Zhong, Binglian;
Li, Chaojie;
Li, Guohuan;
Du, Qingfeng;
He, Songqi

Publication type:

Article

Gout management: Patent analytics and computational drug design explores URAT1 inhibitors landscape.

Published in:

PLoS ONE, 2025, v. 20, n. 8, p. 1, doi. 10.1371/journal.pone.0328559

By:

Zhang, Jiaxin;
Hong, Liang;
Xu, Wenfei;
Zhang, Xin;
Fu, Huina;
Song, Xinan;
Zhao, Jing

Publication type:

Article

A Comparative Study on the Physicochemical Characterization of Chitosan Obtained from Seafood in Uyo Metropolis, Nigeria.

Published in:

Tropical Journal of Natural Product Research, 2025, v. 9, n. 7, p. 3311, doi. 10.26538/tjnpr/v9i7.60

By:

Ewii, Ugochi E.;
Olorunsola, Emmanuel O.;
Onugwu, Adaeze L.;
Ameh, Ojochide M.;
Eke, Euphemia N.;
Iheme, Callistus I.;
Attama, Anthony A.;
Anyiam, Chioma;
Ogbulie, Toochukwu E.

Publication type:

Article

Evaluation of ssDNA aptamer binding to Aurora Kinase A and its cytotoxic effects on HeLa and MCF-7 cancer cell lines.

Published in:

Tropical Journal of Pharmaceutical Research, 2025, v. 24, n. 7, p. 853, doi. 10.4314/tjpr.v24i7.1

By:

Woldekidan, Haregewoin Bezu;
Takundwa, Mutsa M.;
Raj, Deepak B. Thimiri Govinda;
Woldesemayat, Adugna Abdi

Publication type:

Article

Preparation of Bismuth Tripotassium Dicitrate Pharmaceutical Substance.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 4, p. 467, doi. 10.1007/s11094-025-03416-x

By:

Yukhin, Yu. M.;
Shcherbakov, V. P.;
Koledova, E. S.;
Trubin, M. Yu.

Publication type:

Article

Preparation, Characterization, and Transformation Relationship of Gimeracil Crystal Forms P and L.

Published in:

Crystal Research & Technology, 2025, v. 60, n. 8, p. 1, doi. 10.1002/crat.202400279

By:

Zhai, Lihai;
Guo, Lihong;
Li, Jiaming;
Huang, Chao;
Wang, Juju;
Zhang, Guimin

Publication type:

Article

Huanglian Jiedu Decoction improves the"central-peripheral"inflammatory microenvironment and enhances the cognitive function of APP/PS1 mice by inhibiting the activation of NLRP3 inflammasome mediated by gut microbiota.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01180-4

By:

Zhang, Yani;
Wang, Jiahua;
Li, Xuetao;
Guo, Ruibo;
Wang, Liyan;
Liu, Yang;
Yu, Yang;
Kong, Liang

Publication type:

Article

Strain‐Enabled Radical‐Polar Crossover Annulation to Access Spiro‐, Fused‐, and Enantioenriched‐Aza/Oxa‐Bicyclo[3.1.1]Heptanes.

Published in:

Angewandte Chemie, 2025, v. 137, n. 33, p. 1, doi. 10.1002/ange.202506747

By:

Ghorai, Bhismalochan;
Sahana, Buddhadeb;
Hari, Durga Prasad

Publication type:

Article

The efficacy and pharmacological mechanisms of traditional Chinese medicine in the treatment of spinal cord injury.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06129-9

By:

Jiang, Yu;
Liu, Gang;
Deng, Bowen;
Bai, Huizhong;
Mu, Xiaohong

Publication type:

Article

High-throughput screening identifies novel chemical scaffolds targeting Leishmania donovani parasites.

Published in:

World Journal of Microbiology & Biotechnology, 2025, v. 41, n. 7, p. 1, doi. 10.1007/s11274-025-04441-4

By:

Kumari, Diksha;
Jamwal, Vishwani;
Palmo, Tashi;
Kumar, Anuj;
Singh, Kuljit

Publication type:

Article

Advancements in Oral Drug Delivery of Insulin: A Review.

Published in:

2025

By:

Balamurugan, M.;
Sarumathy, S.

Publication type:

Literature Review

Transcriptome analysis of heterografting on key medicinal compounds accumulation in Ziziphi Spinosae Semen.

Published in:

BMC Plant Biology, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12870-025-07104-6

By:

Fu, Xiangrui;
Yu, Yinfeng;
Lu, Zikang;
Wang, Chaohui;
Guo, Lanping;
Yan, Yuping;
Ma, Donglai;
Gu, Xian

Publication type:

Article

Biocatalytic Approaches for the Synthesis of Oxindoles.

Published in:

ChemCatChem, 2025, v. 17, n. 15, p. 1, doi. 10.1002/cctc.202500591

By:

Wang, Hui‐Hui;
Miao, Run‐Ping;
Wang, Yuan‐Fei;
Wan, Nan‐Wei

Publication type:

Article

Chemie im pharmazeutischen Kontext: Drugs, Pro‐ und Codrugs.

Published in:

Chemie in unserer Zeit, 2025, v. 59, n. 4, p. 218, doi. 10.1002/ciuz.202400044

By:

Ducci, Matthias

Publication type:

Article

Targeting neurodegeneration: three machine learning methods for G9a inhibitors discovery using PubChem and scikit-learn.

Published in:

Journal of Computer-Aided Molecular Design, 2025, v. 39, n. 1, p. 1, doi. 10.1007/s10822-025-00642-z

By:

Ivanova, Mariya L.;
Russo, Nicola;
Nikolic, Konstantin

Publication type:

Article

Switchable electrochemical pathways for the selective C(sp3)-Ge bond formation.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-62141-x

By:

Chen, Haifeng;
Zhai, Cai;
Zhang, Huabing;
Zhu, Chen;
Rueping, Magnus

Publication type:

Article

Therapeutic potential of traditional Chinese medicine in diabetic cardiomyopathy: a review.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1532565

By:

Li, Wencan;
Liu, Xiang;
Liu, Zheng;
Xing, Qichang;
Liu, Renzhu;
Wu, Qinxuan;
Zhang, Jiani

Publication type:

Article

Explore the potential mechanism of Huachansu injection against osteosarcoma via metabolomics, network pharmacology and bioinformatics.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01179-x

By:

Meng, Jingjing;
Zhang, Xiangqi;
Xiang, Danfeng;
Liang, Hanlu;
Zhao, Shuai;
Xu, Lingyan;
Yang, Jiao;
Chen, JunJun;
Zhang, Jingxian;
Han, Yonglong

Publication type:

Article

Enantioconvergent Cobalt‐Catalyzed Hydroalkylation for the Construction of Fluoro, Chloro, and Trifluoromethyl Stereogenic Centers.

Published in:

Angewandte Chemie, 2025, v. 137, n. 32, p. 1, doi. 10.1002/ange.202508637

By:

Dhawa, Uttam;
Hu, Xile

Publication type:

Article

SH2 Decarboxylative Monofluoromethylation of Aliphatic Carboxylic Acids Enabled by Nickel/Photoredox Dual Catalysis.

Published in:

Angewandte Chemie, 2025, v. 137, n. 32, p. 1, doi. 10.1002/ange.202507632

By:

Fang, Ting‐Yu;
Jiang, Meng‐Ye;
Zheng, Meng‐Meng;
Ma, Jun‐An;
Zhang, Fa‐Guang

Publication type:

Article

A 19F‐Labeled Probe for the Chiral Discrimination of Thiols and Thioethers.

Published in:

Angewandte Chemie, 2025, v. 137, n. 32, p. 1, doi. 10.1002/ange.202505700

By:

Weng, Jiajin;
Gu, Guangxing;
Zhang, Wei;
Jia, Qi;
Sun, Yining;
Wu, Jian;
Zhao, Yanchuan

Publication type:

Article

The Therapeutic Potential of Melatonin and Its Novel Synthetic Analogs in Circadian Rhythm Sleep Disorders, Inflammation‐Associated Pathologies, and Neurodegenerative Diseases.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 5, p. 1515, doi. 10.1002/med.22117

By:

Ribeiro, Rodrigo F. N.;
Santos, Marco Rios;
Aquino, Maria;
de Almeida, Luis Pereira;
Cavadas, Cláudia;
Silva, Maria Manuel C.

Publication type:

Article

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 5, p. 1423, doi. 10.1002/med.22111

By:

Kontra, Bence;
Mucsi, Zoltán;
Ilaš, Janez;
Dunkel, Petra

Publication type:

Article

The effects of recreational cannabis legalization in Alberta on poison control centre calls and paediatric emergency department visits.

Published in:

Paediatrics & Child Health (1205-7088), 2025, v. 30, n. 4, p. 268, doi. 10.1093/pch/pxae090

By:

Johnson, Sarah;
Allain, Dominic;
Lucyk, Scott;
Simonelli, Michelle;
Loch, Theresa;
Chin, Mathieu

Publication type:

Article

Molecular Editing of Cycloketones via Deoxygenative Coupling Enabled by Dual Photoexcited Palladium and Photoredox Catalysis.

Published in:

Chinese Journal of Chemistry, 2025, v. 43, n. 17, p. 2206, doi. 10.1002/cjoc.70107

By:

Ren, Lixu;
Yuan, Wen;
Zhang, Long;
Li, Daling;
Wei, Siping;
Hao, Na;
Wang, Jun;
Yang, Lin;
Yi, Dong;
Fu, Qiang;
Wei, Jun;
Lu, Ji

Publication type:

Article

Simultaneous determination of AM80 (tamibarotene) and WJD-A-1 in rat plasma by ultra high-performance liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2018, v. 46, p. 1131, doi. 10.1080/21691401.2018.1446443

By:

Leng, Ping;
Yang, Zhao;
Ma, Baohua;
Li, Jing;
Sun, Jialin;
Xie, Yiming;
Sun, Yong

Publication type:

Article

Establishment of THTT derivatives as potential antileishmanial and anti-inflammatory agents through in vitro and in silico investigations.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-12084-6

By:

Sarwar, Sarah;
Masood, Rehana;
Khan, Huma;
Ali, Haleema;
Hassan, Said;
Ahmad, Ajaz;
Shah, Syed Sikandar;
Khan, Naveed;
Khan, Rasool;
Soonmin, Ho;
Ullah, Nadeem;
Ullah, Nazif

Publication type:

Article

Pharmacokinetic study of 3-(4-chlorophenyl)-7-[2-(piperazin-1-yl)ethoxy]-4H-chromen-4-one, a derivative of soybean isoflavone by LC-MS/MS in normal rats.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2025, v. 34, n. 7, p. 633, doi. 10.5246/jcps.2025.07.047

By:

Junrong Hao;
Mengqiang Lian;
Shuang Li;
Hongyan Yin;
Chunyan Guo

Publication type:

Article

A network pharmacology to explore the mechanism of cultured bezoar in vitro for the treatment of colorectal cancer.

Published in:

Pharmacy Practice (1886-3655), 2025, v. 23, n. 2, p. 1, doi. 10.18549/PharmPract.2025.2.3143

By:

Jiaxi Fei;
Qinbo Wang;
Xiaoyan Huang;
Yingjuan Ou;
Junrong Chen

Publication type:

Article

Deguelin's Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571452

By:

Jiang, Wenjie;
Zeng, Jing;
Guo, Li;
Shi, Jianyou;
Lei, Yang

Publication type:

Article

Once‐ Versus Twice‐Daily Tacrolimus Therapy: Does Improved Adherence Lead to Better Efficacy?—A Pharmacokinetic Perspective.

Published in:

Journal of Clinical Pharmacology, 2025, v. 65, n. 8, p. 980, doi. 10.1002/jcph.70021

By:

Dai, Zi‐yan;
Han, Lu;
Wang, Juan;
Liu, Xiao‐qin;
Chen, Rui;
Jiao, Zheng

Publication type:

Article

Increased eye irritation alert.

Published in:: Nursing & Residential Care, 2015, v. 17, n. 9, p. 487
Publication type:: Article

Cantharidin 0.7% topical solution (YCANTH®) in molluscum contagiosum: a profile of its use.

Published in:

Drugs & Therapy Perspectives, 2025, v. 41, n. 2, p. 47, doi. 10.1007/s40267-024-01131-3

By:

Zhuang-Yan, Amy;
Blair, Hannah A.

Publication type:

Article

Paliperidone palmitate intramuscular 6-monthly formulation in schizophrenia: a profile of its use.

Published in:

Drugs & Therapy Perspectives, 2022, v. 38, n. 8, p. 335, doi. 10.1007/s40267-022-00931-9

By:

Blair, Hannah A.

Publication type:

Article

Viloxazine for attention-deficit hyperactivity disorder: a new formulation for a new indication.

Published in:

Drugs & Therapy Perspectives, 2022, v. 38, n. 2, p. 77, doi. 10.1007/s40267-022-00892-z

By:

Balasundaram, Mahesh Kumar;
Singh, Alok

Publication type:

Article

Oritavancin (KIMYRSA™) in acute bacterial skin and skin structure infections: a profile of its use in the USA.

Published in:

Drugs & Therapy Perspectives, 2022, v. 38, n. 2, p. 57, doi. 10.1007/s40267-021-00888-1

By:

Heo, Young-A

Publication type:

Article

Computational Drug Design Approaches for the Identification of Novel Antidiabetic Compounds from Natural Resources through Molecular Docking, ADMET, and Toxicological Studies.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 1, p. 1057, doi. 10.1007/s12013-024-01540-1

By:

Akter, Bakul;
Uddin, Md. Sohorab;
Islam, Mohammad Rashedul;
Ahamed, Kutub Uddin;
Aktar, Most. Nazmin;
Hossain, Mohammed Kamrul;
Salamatullah, Ahmad Mohammad;
Bourhia, Mouhammed

Publication type:

Article

Can We Rely on Computational Predictions To Correctly Identify Ligand Binding Sites on Novel Protein Drug Targets? Assessment of Binding Site Prediction Methods and a Protocol for Validation of Predicted Binding Sites.

Published in:

Cell Biochemistry & Biophysics, 2017, v. 75, n. 1, p. 15, doi. 10.1007/s12013-016-0769-y

By:

Broomhead, Neal;
Soliman, Mahmoud

Publication type:

Article

Data Science Projects in Pharmaceutical Industry.

Published in:

Journal of Information Science & Engineering, 2021, v. 37, n. 5, p. 1135, doi. 10.6688/JISE.202109_37(5).0010

By:

PESQUEIRA, ANTÓNIO MIGUEL;
SOUSA, MARIA JOSÉ;
MELÉ, PERE MERCADÉ;
ROCHA, ÁLVARO;
SOUSA, MIGUEL;
DA COSTA, RENATO LOPES

Publication type:

Article

Ergometrine stability in postpartum haemorrhage kits: Does temperature and light matter?

Published in:

Australian & New Zealand Journal of Obstetrics & Gynaecology, 2020, v. 60, n. 3, p. 344, doi. 10.1111/ajo.13046

By:

Donnan, Finbarr;
Senarathna, S.M.D.K. Ganga;
Ware, Benjamin;
Rawlins, Matthew D.M.;
Dontham, Chandrakala;
Chuang, Victor T.G.;
Batty, Kevin T.

Publication type:

Article

Solid oral medications' suitability for use in enteral feeding tubes.

Published in:

Nursing in Critical Care, 2022, v. 27, n. 5, p. 698, doi. 10.1111/nicc.12729

By:

Teder, Kersti;
Jõhvik, Liisa;
Meos, Andres;
Saar, Marika;
Visbek, Alesya;
Volmer, Daisy;
Karjagin, Juri

Publication type:

Article

Capillary electrophoresis in pharmaceutical and biomedical analysis.

Published in:

Analytical & Bioanalytical Chemistry, 2005, v. 381, n. 1, p. 93, doi. 10.1007/s00216-004-2902-9

By:

Veuthey, Jean-Luc

Publication type:

Article

Sample preparation for pharmaceutical analysis.

Published in:

Analytical & Bioanalytical Chemistry, 2005, v. 381, n. 1, p. 75, doi. 10.1007/s00216-004-2894-5

By:

Xiaofang Fu;
Yiping Liao;
Huwei Liu

Publication type:

Article

A mini-review of mass spectrometry using high-performance FTICR-MS methods.

Published in:

Analytical & Bioanalytical Chemistry, 2004, v. 378, n. 4, p. 1048, doi. 10.1007/s00216-003-2446-4

By:

Heeren, R. M. A.;
Kleinnijenhuis, A. J.;
McDonnell, L. A.;
Mize, T. H.

Publication type:

Article

Immunoaffinity capillary electrophoresis applications of clinical and pharmaceutical relevance.

Published in:

Analytical & Bioanalytical Chemistry, 2004, v. 378, n. 1, p. 37, doi. 10.1007/s00216-003-2326-y

By:

Guzman, Norberto A.

Publication type:

Article