Works matching Cyclin-dependent kinase inhibitor-2A

Results: 251

P16 as a Prognostic Biomarker for Nonoropharyngeal Squamous Cell Cancers: Avatar or Mirage?

Published in:

2018

By:

Fakhry, Carole;
Ferris, Robert L

Publication type:

Editorial

Cyclin D1 immunohistochemical expression and somatic mutations in canine oral melanoma.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 2, p. 231, doi. 10.1111/vco.12539

By:

Zamboni, Clarissa;
Brocca, Ginevra;
Ferraresso, Serena;
Ferro, Silvia;
Sammarco, Alessandro;
Dal Corso, Chiara;
Iussich, Selina;
Andres, Paloma J.;
Martìnez de Merlo, Elena M.;
Cavicchioli, Laura;
Zappulli, Valentina;
Castagnaro, Massimo

Publication type:

Article

Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma.

Published in:

Veterinary & Comparative Oncology, 2019, v. 17, n. 3, p. 308, doi. 10.1111/vco.12473

By:

Giannuzzi, Diana;
Marconato, Laura;
Elgendy, Ramy;
Ferraresso, Serena;
Scarselli, Elisa;
Fariselli, Piero;
Nicosia, Alfredo;
Pegolo, Sara;
Leoni, Guido;
Laganga, Paola;
Leone, Vito F.;
Giantin, Mery;
Troise, Fulvia;
Dacasto, Mauro;
Aresu, Luca

Publication type:

Article

CDKN2A, a key gene in copper-induced cell death model, influencing melanoma invasion and apoptosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01992-8

By:

Li, Jing;
Yang, Xi;
Yin, Cunli;
Li, Siru;
Xu, Yan;
Liu, Bin

Publication type:

Article

Thrombin Induces Angiotensin II-Mediated Senescence in Atrial Endothelial Cells: Impact on Pro-Remodeling Patterns.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 10, p. 1570, doi. 10.3390/jcm8101570

By:

Hasan, Hira;
Park, Sin-Hee;
Auger, Cyril;
Belcastro, Eugenia;
Matsushita, Kensuke;
Marchandot, Benjamin;
Lee, Hyun-Ho;
Qureshi, Abdul Wahid;
Kauffenstein, Gilles;
Ohlmann, Patrick;
Schini-Kerth, Valérie B;
Jesel, Laurence;
Morel, Olivier

Publication type:

Article

Low prevalence of human papillomavirus in oral cavity squamous cell carcinoma in Queensland, Australia.

Published in:

ANZ Journal of Surgery, 2017, v. 87, n. 9, p. 714, doi. 10.1111/ans.13607

By:

Emmett, Sarah;
Jenkins, Glenn;
Boros, Samuel;
Whiteman, David C.;
Panizza, Benedict;
Antonsson, Annika

Publication type:

Article

Prevalence of cervical human papillomavirus is associated with p16 expression and irregular menstrual cycles among married Jordanian women.

Published in:

European Journal of Gynaecological Oncology, 2018, v. 39, n. 5, p. 780, doi. 10.12892/ejgo4318.2018

By:

Bodoor, K.;
Melhem, D.;
Shotar, A.;
Alkhatib, A.;
Batiha, O.;
Abu-sheikha, A.;
Haddad, Y.

Publication type:

Article

rs77283072 influences breast cancer susceptibility by regulating CDKN2A expression.

Published in:

Oncology Letters, 2023, v. 25, n. 2, p. N.PAG, doi. 10.3892/ol.2023.13662

By:

He, Guang-Huan;
Liu, Shao-Dong;
Shi, Xiao-Qian;
Chen, Ying;
Su, Li;
Shi, Qiao-Na;
Sun, Chang

Publication type:

Article

mRNA expression and DNA methylation analysis of the inhibitory mechanism of H2O2 on the proliferation of A549 cells.

Published in:

Oncology Letters, 2020, v. 20, n. 6, p. N.PAG, doi. 10.3892/ol.2020.12151

By:

Li, Yepeng;
Wei, Zhongheng;
Huang, Shiqing;
Yang, Bo

Publication type:

Article

Identification of hub genes associated with esophageal cancer progression using bioinformatics analysis.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12077

By:

JIANGFEN LI;
YUFANG XIE;
XUELI WANG;
CHENHAO JIANG;
XIN YUAN;
ANZHI ZHANG;
LAN YANG;
CHUNXIA LIU;
HONG ZOU;
FENG LI;
JIANMING HU

Publication type:

Article

Identification of hub genes involved in the occurrence and development of hepatocellular carcinoma via bioinformatics analysis.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1695, doi. 10.3892/ol.2020.11752

By:

Mi, Ningning;
Cao, Jie;
Zhang, Jinduo;
Fu, Wenkang;
Huang, Chongfei;
Gao, Long;
Yue, Ping;
Bai, Bing;
Lin, Yanyan;
Meng, Wenbo;
Li, Xun

Publication type:

Article

Identification of key genes for guiding chemotherapeutic management in ovarian cancer using translational bioinformatics.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1345, doi. 10.3892/ol.2020.11672

By:

Yuan, Danni;
Zhou, Haohan;
Sun, Hongyu;
Tian, Rui;
Xia, Meihui;
Sun, Liankun;
Liu, Yanan

Publication type:

Article

Integrated analysis revealing genome-wide chromosomal copy number variation in supraglottic laryngeal squamous cell carcinoma.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1201, doi. 10.3892/ol.2020.11653

By:

Li, Dongjie;
Wang, Xianfu;
Lu, Shunfei;
Wang, Ping;
Wang, Xin;
Yin, Wanzhong;
Zhu, Wei;
Li, Shibo

Publication type:

Article

Exploration of the molecular mechanisms of cervical cancer based on mRNA expression profiles and predicted microRNA interactions.

Published in:

Oncology Letters, 2018, v. 15, n. 6, p. 8965, doi. 10.3892/ol.2018.8494

By:

Zhao, Liang;
Zhang, Zhechao;
Lou, Hongyan;
Liang, Jingjing;
Yan, Xiaojian;
Li, WENfENg;
Xu, YunshENg;
Ou, Rongying

Publication type:

Article

Analysis of YAP1 and TAZ expression by immunohistochemical staining in malignant mesothelioma and reactive mesothelial cells.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6825, doi. 10.3892/ol.2018.8225

By:

Takehara, Yusuke;
Yamochi, Toshiko;
Nagumo, Tasuku;
Cho, Tomonari;
Urushibara, Fumihiko;
Ono, Kohei;
Fujii, Tomonori;
Okamoto, Naoko;
Sasaki, Yosuke;
Tazawa, Sakiko;
Honma, Mayumi;
Norose, Tomoko;
Shiozawa, Eisuke;
Tate, Genshu;
Takimoto, Masafumi

Publication type:

Article

p16 as a prognostic factor for the response to induction chemotherapy in advanced hypopharyngeal squamous cell carcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6571, doi. 10.3892/ol.2018.8138

By:

Lee, Joon Kyoo;
Lee, Kyung-Hwa;
Kim, Sun-Ae;
Kweon, Sun Seog;
Cho, Sang-Hee;
Shim, Hyun-Jeong;
Bae, Woo-Kyun;
Chung, Ik-Joo;
Chung, Woong-Ki;
Yoon, Tae Mi;
Lim, Sang Chul;
Lee, Dong Hoon

Publication type:

Article

Auxiliary diagnostic value of p16 amplification combined with the detection of heterozygous and homozygous loss for urothelial carcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6533, doi. 10.3892/ol.2018.8137

By:

Mao, Xiaopeng;
Li, Baimou;
Liang, Ying;
Li, Shuhua;
Zhou, Jianwen;
He, Qiong;
Jiang, Neng;
Chen, Yangshan;
Sun, Yu;
Cui, Yongmei;
Jiang, Wenting;
Wang, Han;
Wang, Liantang;
Ke, Zunfu

Publication type:

Article

Identification of candidate target genes of genomic aberrations in esophageal squamous cell carcinoma.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2956, doi. 10.3892/ol.2016.4947

By:

TIAN-YUN SHEN;
LI-LI MEI;
YUN-TAN QIU;
ZHI-ZHOU SHI

Publication type:

Article

A novel IGH@ gene rearrangement associated with CDKN2A/B deletion in young adult B-cell acute lymphoblastic leukemia.

Published in:

Oncology Letters, 2016, v. 11, n. 3, p. 2117, doi. 10.3892/ol.2016.4169

By:

OTHMAN, MONEEB A. K.;
GRYGALEWICZ, BEATA;
PIENKOWSKA-GRELA, BARBARA;
RYGIER, JOLANTA;
EJDUK, ANNA;
RINCIC, MARTINA;
MELO, JOANA B.;
CARREIRA, ISABEL M.;
MEYER, BRITTA;
LIEHR, THOMAS

Publication type:

Article

Effect of tumor suppressor gene cyclin-dependent kinase inhibitor 2A wild-type and A148T mutant on the cell cycle of human ovarian cancer cells.

Published in:

Oncology Letters, 2014, v. 7, n. 4, p. 1229, doi. 10.3892/ol.2014.1867

By:

ZEHUA BIAN;
YANG YU;
TERIGELE YANG;
CHAO QUAN;
WENJING SUN;
SONGBIN FU

Publication type:

Article

Early Onset Primary Hyperparathyroidism Associated with a Novel Germline Mutation in CDKN1B.

Published in:

Case Reports in Endocrinology, 2015, v. 2015, p. 1, doi. 10.1155/2015/510985

By:

Elston, Marianne S.;
Meyer-Rochow, Goswin Y.;
Dray, Michael;
Swarbrick, Michael;
Conaglen, John V.

Publication type:

Article

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma.

Published in:

Oncogene, 2015, v. 34, n. 13, p. 1619, doi. 10.1038/onc.2014.98

By:

Li, X;
Liu, Y;
Granberg, K J;
Wang, Q;
Moore, L M;
Ji, P;
Gumin, J;
Sulman, E P;
Calin, G A;
Haapasalo, H;
Nykter, M;
Shmulevich, I;
Fuller, G N;
Lang, F F;
Zhang, W

Publication type:

Article

Genetic profile of naïve untreated primary cutaneous melanomas with a negative sentinel lymph node.

Published in:

Clinical & Experimental Dermatology, 2020, v. 45, n. 8, p. 1059, doi. 10.1111/ced.14321

By:

Yang, K.;
Oh, K. S.;
Mahalingam, M.

Publication type:

Article

CDK4/6 Inhibitor Palbociclib Amplifies the Radiosensitivity to Nasopharyngeal Carcinoma Cells via Mediating Apoptosis and Suppressing DNA Damage Repair.

Published in:

OncoTargets & Therapy, 2019, v. 12, p. 11107, doi. 10.2147/OTT.S234221

By:

Xie, Xianhe;
Zheng, Weili;
Chen, Ting;
Lin, Wanzun;
Liao, Ziyuan;
Liu, Junjin;
Ding, Yin

Publication type:

Article

Local genetic ancestry in CDKN2B-AS1 is associated with primary open-angle glaucoma in an African American cohort extracted from de-identified electronic health records.

Published in:

BMC Medical Genomics, 2018, v. 11, n. 3, p. N.PAG, doi. 10.1186/s12920-018-0392-4

By:

Restrepo, Nicole A.;
Laper, Sarah M.;
Farber-Eger, Eric;
Crawford, Dana C.

Publication type:

Article

Association of good oncological response to therapy with the development of rheumatic immune‐related adverse events following PD‐1 inhibitor therapy.

Published in:

International Journal of Rheumatic Diseases, 2019, v. 22, n. 2, p. 297, doi. 10.1111/1756-185X.13444

By:

Liew, David F. L.;
Leung, Jessica L. Y.;
Liu, Bonnia;
Cebon, Jonathan;
Frauman, Albert G.;
Buchanan, Russell R. C.

Publication type:

Article

Analysis of sequence variants in the 3'UTR of CDKN2A gene in melanoma patients.

Published in:

Contemporary Oncology / Współczesna Onkologia, 2015, v. 19, n. 4, p. 276, doi. 10.5114/wo.2015.54227

By:

Przybyła, Anna;
Lamperska, Katarzyna;
Mackiewicz, Andrzej

Publication type:

Article

Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies.

Published in:

BMC Genomics, 2011, v. 12, p. 1, doi. 10.1186/1471-2164-12-230

By:

Parisi, Fabio;
Ariyan, Stephan;
Narayan, Deepak;
Bacchiocchi, Antonella;
Hoyt, Kathleen;
Cheng, Elaine;
Xu, Fang;
Li, Peining;
Halaban, Ruth;
Kluger, Yuval

Publication type:

Article

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1408-5

By:

Andries, Vanessa;
Vandepoele, Karl;
Staes, Katrien;
Berx, Geert;
Bogaert, Pieter;
Van Isterdael, Gert;
Ginneberge, Daisy;
Parthoens, Eef;
Vandenbussche, Jonathan;
Gevaert, Kris;
van Roy, Frans

Publication type:

Article

Updated evidence‐based clinical practice guidelines for the diagnosis and management of melanoma: definitive excision margins for primary cutaneous melanoma.

Published in:

Medical Journal of Australia, 2018, v. 208, n. 3, p. 137, doi. 10.5694/mja17.00278

By:

Sladden, Michael J;
Nieweg, Omgo E;
Howle, Julie;
Coventry, Brendon J;
Thompson, John F

Publication type:

Article

C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.

Published in:

Molecular & Cellular Biochemistry, 2019, v. 454, n. 1/2, p. 87, doi. 10.1007/s11010-018-3455-0

By:

Li, Xin;
Dong, Ming;
Zhou, Jianping;
Zhu, Dehua;
Zhao, Jinbo;
Sheng, Weiwei

Publication type:

Article

A novel interplay between HOTAIR and DNA methylation in osteosarcoma cells indicates a new therapeutic strategy.

Published in:

Journal of Cancer Research & Clinical Oncology, 2017, v. 143, n. 11, p. 2189, doi. 10.1007/s00432-017-2478-3

By:

Li, Xingang;
Lu, Hongming;
Fan, Guilian;
He, Miao;
Sun, Yu;
Xu, Kai;
Shi, Fengjun

Publication type:

Article

Combination of cyclin-dependent kinase and immune checkpoint inhibitors for the treatment of bladder cancer.

Published in:

Cancer Immunology, Immunotherapy, 2020, v. 69, n. 11, p. 2305, doi. 10.1007/s00262-020-02609-5

By:

Long, Qilai;
Ma, Ai-Hong;
Zhang, Hongyong;
Cao, Zhixiu;
Xia, Roger;
Lin, Tzu-Yin;
Sonpavde, Guru P.;
de Vere White, Ralph;
Guo, Jianming;
Pan, Chong-Xian

Publication type:

Article

Gender Differences and Outcomes in Melanoma Patients.

Published in:

Oncology & Therapy, 2020, v. 8, n. 1, p. 103, doi. 10.1007/s40487-020-00109-1

By:

Morgese, Francesca;
Sampaolesi, Caterina;
Torniai, Mariangela;
Conti, Alessandro;
Ranallo, Nicoletta;
Giacchetti, Alfredo;
Serresi, Stefano;
Onofri, Azzurra;
Burattini, Michela;
Ricotti, Giuseppe;
Berardi, Rossana

Publication type:

Article

Global activation of oncogenic pathways underlies therapy resistance in diffuse midline glioma.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00992-9

By:

Georgescu, M.-M.;
Islam, M. Z.;
Li, Y.;
Circu, M. L.;
Traylor, J.;
Notarianni, C. M.;
Kline, C. N.;
Burns, D. K.

Publication type:

Article

Risk factors of recurrence and distant metastasis in primary cutaneous melanoma in Taiwan.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00386-4

By:

Lee, Tung-Lin;
Liao, Yi-Hua;
Liau, Jau-Yu;
Sheen, Yi-Shuan

Publication type:

Article

Prevalence of Germline BAP1, CDKN2A, and CDK4 Mutations in an Australian Population-Based Sample of Cutaneous Melanoma Cases.

Published in:

Twin Research & Human Genetics, 2015, v. 18, n. 2, p. 126, doi. 10.1017/thg.2015.12

By:

Aoude, Lauren G.;
Gartside, Michael;
Johansson, Peter;
Palmer, Jane M.;
Symmons, Judith;
Martin, Nicholas G.;
Montgomery, Grant W.;
Hayward, Nicholas K.

Publication type:

Article

HEDGEHOG/GLI-E2F1 axis modulates iASPP expression and function and regulates melanoma cell growth.

Published in:

Cell Death & Differentiation, 2015, v. 22, n. 12, p. 2006, doi. 10.1038/cdd.2015.56

By:

Pandolfi, S;
Montagnani, V;
Lapucci, A;
Stecca, B

Publication type:

Article

Insulinoma-associated protein 1 controls nasopharyngeal carcinoma to radiotherapy by modulating cyclin D1-dependent DNA repair machinery.

Published in:

Carcinogenesis, 2020, v. 41, n. 3, p. 326, doi. 10.1093/carcin/bgz101

By:

Song, Ruibiao;
Wei, Xing;
Wang, You;
Hu, Shousen;
Ba, Yunpeng;
Xiao, Xiyan;
Zhang, Jianzhong

Publication type:

Article

Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer.

Published in:

Science Signaling, 2017, v. 10, n. 461, p. 1, doi. 10.1126/scisignal.aaf8223

By:

Gamell, Cristina;
Gulati, Twishi;
Levav-Cohen, Yaara;
Young, Richard J.;
Do, Hongdo;
Pilling, Pat;
Takano, Elena;
Watkins, Neil;
Fox, Stephen B.;
Russell, Prudence;
Ginsberg, Doron;
Monahan, Brendon J.;
Wright, Gavin;
Dobrovic, Alex;
Haupt, Sue;
Solomon, Ben;
Haupt, Ygal

Publication type:

Article

Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma.

Published in:

BMC Medical Genomics, 2020, v. 13, p. 1, doi. 10.1186/s12920-020-0685-2

By:

Zhang, Di;
Xia, Junfeng

Publication type:

Article

The driving power of the cell cycle: cyclin-dependent kinases, cyclins and their inhibitors.

Published in:

Bratislava Medical Journal / Bratislavské Lekárske Listy, 2023, v. 124, n. 4, p. 261, doi. 10.4149/BLL_2023_039

By:

HIVES, Mark;
JURECEKOVA, Jana;
HIVES HOLECKOVA, Klaudia;
KLIMENT, Jan;
KMETOVA SIVONOVA, Monika

Publication type:

Article

Expression of p16<sup>INK4A</sup> in cervical precancerous lesions that is unlikely to be preventable by human papillomavirus vaccines.

Published in:

2016

By:

Badiga, Suguna;
Chambers, Michelle M.;
Huh, Warner;
Eltoum, Isam‐Eldin A.;
Piyathilake, Chandrika J.;
Eltoum, Isam-Eldin A

Publication type:

journal article

Next-generation sequencing survey of biliary tract cancer reveals the association between tumor somatic variants and chemotherapy resistance.

Published in:

2016

By:

Ahn, Daniel H.;
Javle, Milind;
Ahn, Chul W.;
Jain, Apurva;
Mikhail, Sameh;
Noonan, Anne M.;
Wu, Christina;
Shroff, Rachna T.;
Chen, James L.;
Bekaii‐Saab, Tanios;
Ciombor, Kristen;
Bekaii-Saab, Tanios

Publication type:

journal article

Pyrimidine‐based pyrazoles as cyclin‐dependent kinase 2 inhibitors: Design, synthesis, and biological evaluation.

Published in:

Chemical Biology & Drug Design, 2018, v. 92, n. 3, p. 1683, doi. 10.1111/cbdd.13334

By:

Vekariya, Mayur K.;
Vekariya, Rajesh H.;
Brahmkshatriya, Pathik S.;
Shah, Nisha K.

Publication type:

Article

Tubule-specific protein nanocages potentiate targeted renal fibrosis therapy.

Published in:

Journal of Nanobiotechnology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12951-021-00900-w

By:

Zhang, Xuan;
Chen, Qian;
Zhang, Liyuan;
Zheng, Haiping;
Lin, Chunjie;
Yang, Qunfang;
Liu, Tao;
Zhang, Haigang;
Chen, Xiaohong;
Ren, Lei;
Shan, Wenjun

Publication type:

Article

Comprehensive Analysis of PTEN in Primary Cutaneous Melanoma.

Published in:

Folia Biologica (00155500), 2020, v. 66, n. 1, p. 7, doi. 10.14712/fb2020066010007

By:

NĚMEJCOVÁ, K.;
DUNDR, P.;
JAKŠA, R.;
BÁRTŮ, M.;
STRUŽINSKÁ, I.;
HOJNÝ, J.;
HÁJKOVÁ, N.;
KODET, O.

Publication type:

Article

A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report.

Published in:

2016

By:

Barnes, David J.;
Hookway, Edward;
Athanasou, Nick;
Takeshi Kashima;
Oppermann, Udo;
Hughes, Simon;
Swan, Daniel;
Lueerssen, Dietrich;
Anson, John;
Hassan, A. Bassim;
Kashima, Takeshi

Publication type:

journal article

Genomic and transcriptomic landscape of conjunctival melanoma.

Published in:

PLoS Genetics, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.pgen.1009201

By:

Cisarova, Katarina;
Folcher, Marc;
El Zaoui, Ikram;
Pescini-Gobert, Rosanna;
Peter, Virginie G.;
Royer-Bertrand, Beryl;
Zografos, Leonidas;
Schalenbourg, Ann;
Nicolas, Michael;
Rimoldi, Donata;
Leyvraz, Serge;
Riggi, Nicolò;
Moulin, Alexandre P.;
Rivolta, Carlo

Publication type:

Article

Deciphering the vascular labyrinth: role of microRNAs and candidate gene SNPs in brain AVM development – literature review.

Published in:

2020

By:

Florian, Ioan Alexandru;
Timiș, Teodora Larisa;
Ungureanu, Gheorghe;
Florian, Ioan Stefan;
Bălașa, Adrian;
Berindan-neagoe, Ioana

Publication type:

Literature Review