Interatrial block and atrial remodeling assessed using speckle tracking echocardiography.

Lacalzada-Almeida, Juan; Izquierdo-Gómez, María Manuela; Belleyo-Belkasem, Carima; Barrio-Martínez, Patricia; García-Niebla, Javier; Elosua, Roberto; Jiménez-Sosa, Alejandro; Escobar-Robledo, Luis Alberto; Bayés de Luna, Antonio; Izquierdo-Gómez, María Manuela; Barrio-Martínez, Patricia; García-Niebla, Javier; Jiménez-Sosa, Alejandro; Bayés de Luna, Antonio

<bold>Background: </bold>To evaluate the possibility of left atrial (LA) remodeling using speckle tracking echocardiography (STE) in patients with interatrial block (IAB).<bold>Methods: </bold>We performed a cross-sectional study with three groups of patients: 56 without IAB, 21 with partial IAB (pIAB), and 22 with advanced IAB (aIAB). Transthoracic echocardiographic (TTE) STE was performed and clinical and echocardiographic findings were analyzed.<bold>Results: </bold>TTE showed higher LA volume/body surface area in the patients with IAB. With STE, the absolute value of strain rate during atrial booster pump function (SRa) and early reservoir period (SRs) decreased in the pIAB group and even more in the aIAB group, compared to the group without IAB. The independent variables were the echocardiographic measures of LA size and function. After adjusting for confounders, both multiple linear regression and multivariate multinomial regression showed good correlation with dependent variables: longer P-wave duration on electrocardiography and with the type of IAB, respectively. SRa (p < 0.001), SRs (p < 0.001), and maximal peak LA longitudinal strain in the reservoir period (p = 0.009) were independently associated with P-wave duration. SRa was also associated with the presence of pIAB (OR = 11.5; 95% confidence interval (CI): 2.7-49.0; p = 0.001) and aIAB, (OR = 98.2; 95% CI: 16-120.4; p < 0.001) and SRs was associated with pIAB (OR: 0.03; CI: 0.003-0.29; p = 0.003) and with aIAB (OR: 0.008; CI: 0.001-0.12; p = 0.004).<bold>Conclusions: </bold>IAB correlates directly with structural remodeling and a decrease in the absolute value of LA SRa and SRs determined using STE.

MITRAL valve surgery; ECHOCARDIOGRAPHY; CROSS-sectional method; REGRESSION analysis; MULTIVARIATE analysis; ACTION potentials; CARDIOVASCULAR system physiology; DOPPLER echocardiography; ELECTROCARDIOGRAPHY; HEART atrium; HEART beat; PREDICTIVE tests; CASE-control method

BMC Cardiovascular Disorders, 2018, Vol 18, p1

1471-2261

Academic Journal

10.1186/s12872-018-0776-6