Works matching DE "DUAL specificity phosphatase 1"

Results: 136

The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 971, doi. 10.1038/nsmb.2099

By:

Ungureanu, Daniela;
Jinhua Wu;
Pekkala, Tuija;
Niranjan, Yashavanthi;
Young, Clifford;
Jensen, Ole N.;
Chong-Feng Xu;
Neubert, Thomas A.;
Skoda, Radek C.;
Hubbard, Stevan R.;
Silvennoinen, Olli

Publication type:

Article

Identification of novel inhibitors of mitogen-activated protein kinase phosphatase-1 with structure-based virtual screening.

Published in:

Journal of Computer-Aided Molecular Design, 2011, v. 25, n. 5, p. 469, doi. 10.1007/s10822-011-9432-2

By:

Park, Hwangseo;
Jeon, Jeong-Yi;
Kim, Song;
Jeong, Dae;
Ryu, Seong

Publication type:

Article

DUSP facilitates RPMI8226 myeloma cell aging and inhibited TLR4 expression.

Published in:

European Review for Medical & Pharmacological Sciences, 2018, v. 22, n. 18, p. 6030

By:

XIAN, F.;
HU, X.;
HU, X. S.;
CHEN, Q. L.;
QIN, J.;
BIE, J.

Publication type:

Article

Effect of FGF2 on the activity of SPRYs/DUSP6/ ERK signaling pathway in endometrial glandular epithelial cells of endometriosis.

Published in:

European Review for Medical & Pharmacological Sciences, 2018, v. 22, n. 6, p. 1554

By:

LI, M. -J.;
YU, X. -Y.;
QU, H. -M.;
LIU, J.;
ZHANG, Y. -H.;
WANG, X. -T.;
CHU, Y. -L.

Publication type:

Article

The reduced SCFA-producing gut microbes are involved in the inflammatory activation in Kawasaki disease.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1124118

By:

Fangyan Wang;
Fanyu Qian;
Qihao Zhang;
Jian Zhao;
Jianke Cen;
Jiamin Zhang;
Jinhui Zhou;
Ming Luo;
Chang Jia;
Xing Rong;
Maoping Chu

Publication type:

Article

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos.

Published in:

Animal Cells & Systems, 2020, v. 24, n. 6, p. 359, doi. 10.1080/19768354.2020.1847732

By:

Umair, Zobia;
Kumar, Santosh;
Rafiq, Khezina;
Kumar, Vijay;
Reman, Zia Ur;
Lee, Seung-Hwan;
Kim, SungChan;
Lee, Jae-Yong;
Lee, Unjoo;
Kim, Jaebong

Publication type:

Article

Effect of miR-101 on the Proliferation and Apoptosis of Goat Hair Follicle Stem Cells.

Published in:

Genes, 2022, v. 13, n. 6, p. 1035, doi. 10.3390/genes13061035

By:

Qu, Jingwen;
Wu, Xi;
Wang, Qiang;
Wang, Jian;
Sun, Xiaomei;
Ji, Dejun;
Li, Yongjun

Publication type:

Article

MAPKs in development: insights from Dictyostelium signaling pathways.

Published in:

Biomolecular Concepts, 2011, v. 2, n. 1/2, p. 39, doi. 10.1515/BMC.2011.004

By:

Hadwiger, Jeffrey A.;
Hoai-Nghia Nguyen

Publication type:

Article

Cyclin-dependent kinases as therapeutic targets in melanoma.

Published in:

Pigment Cell & Melanoma Research, 2014, v. 27, n. 3, p. 351, doi. 10.1111/pcmr.12211

By:

Miller, David M.;
Flaherty, Keith T.

Publication type:

Article

Co-Stimulation with TWEAK and TGF-β1 Induces Steroid-Insensitive TSLP and CCL5 Production in BEAS-2B Human Bronchial Epithelial Cells.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 21, p. 11625, doi. 10.3390/ijms252111625

By:

Abe, Sumiko;
Harada, Norihiro;
Sandhu, Yuuki;
Sasano, Hitoshi;
Tanabe, Yuki;
Ueda, Shoko;
Nishimaki, Takayasu;
Sato, Yoshihiko;
Takeshige, Tomohito;
Harada, Sonoko;
Akiba, Hisaya;
Takahashi, Kazuhisa

Publication type:

Article

Dynamics of Dual Specificity Phosphatases and Their Interplay with Protein Kinases in Immune Signaling.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2086, doi. 10.3390/ijms20092086

By:

Subbannayya, Yashwanth;
Pinto, Sneha M.;
Bösl, Korbinian;
Prasad, T. S. Keshava;
Kandasamy, Richard K.

Publication type:

Article

Differential Responses of OsMPKs in IR56 Rice to Two BPH Populations of Different Virulence Levels.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 4030, doi. 10.3390/ijms19124030

By:

Nanda, Satyabrata;
Wan, Pin-Jun;
Yuan, San-Yue;
Lai, Feng-Xiang;
Wang, Wei-Xia;
Fu, Qiang

Publication type:

Article

Epigallocatechin-3-Gallate Suppresses Human Herpesvirus 8 Replication and Induces ROS Leading to Apoptosis and Autophagy in Primary Effusion Lymphoma Cells.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 1, p. 16, doi. 10.3390/ijms19010016

By:

Tsai, Ching-Yi;
Chen, Chang-Yu;
Chiou, Yee-Hsuan;
Shyu, Huey-Wen;
Lin, Kuan-Hua;
Chou, Miao-Chen;
Huang, Mei-Han;
Wang, Yi-Fen

Publication type:

Article

Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 8, p. 1199, doi. 10.3390/ijms17081199

By:

Xue Yao;
Dang Wu;
Ningning Dong;
Ping Ouyang;
Jiaqian Pu;
Qian Hu;
Jingyuan Wang;
Weiqiang Lu;
Jin Huang

Publication type:

Article

Identification of inhibitors that target dual-specificity phosphatase 5 provide new insights into the binding requirements for the two phosphate pockets.

Published in:

BMC Biochemistry, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12858-015-0048-3

By:

Neumann, Terrence S.;
Span, Elise A.;
Kalous, Kelsey S.;
Bongard, Robert;
Gastonguay, Adam;
Lepley, Michael A.;
Kutty, Raman G.;
Nayak, Jaladhi;
Bohl, Chris;
Lange, Rachel G.;
Sarker, Majher I.;
Talipov, Marat R.;
Rathore, Rajendra;
Ramchandran, Ramani;
Sem, Daniel S.

Publication type:

Article

Protein expression, characterization and activity comparisons of wild type and mutant DUSP5 proteins.

Published in:

BMC Biochemistry, 2014, v. 15, n. 1, p. 54, doi. 10.1186/s12858-014-0027-0

By:

Nayak, Jaladhi;
Gastonguay, Adam J.;
Talipov, Marat R.;
Vakeel, Padmanabhan;
Span, Elise A.;
Kalous, Kelsey S.;
Kutty, Raman G.;
Jensen, Davin R.;
Pokkuluri, Phani Raj;
Sem, Daniel S.;
Rathore, Rajendra;
Ramchandran, Ramani

Publication type:

Article

Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells.

Published in:

Journal of Molecular Medicine, 2012, v. 90, n. 2, p. 149, doi. 10.1007/s00109-011-0814-7

By:

Morgan, Michael;
Onono, Fredrick;
Spielmann, H.;
Subramanian, Thangaiah;
Scherr, Michaela;
Venturini, Letizia;
Dallmann, Iris;
Ganser, Arnold;
Reuter, Christoph

Publication type:

Article

Comparative Action of Cardiotonic Steroids on Intracellular Processes in Rat Cortical Neurons.

Published in:

Biochemistry (00062979), 2018, v. 83, n. 2, p. 140, doi. 10.1134/S0006297918020062

By:

Lopachev, A. V.;
Lopacheva, O. M.;
Nikiforova, K. A.;
Filimonov, I. S.;
Fedorova, T. N.;
Akkuratov, E. E.

Publication type:

Article

Personalised medical management of patients with melanoma (part 2).

Published in:

Nowotwory, 2021, v. 71, n. 4, p. 251, doi. 10.5603/NJO.2021.0045

By:

Gil, Justyna;
Łaczmańska, Izabela;
Sąsiadek, Maria M.;
Ziętek, Marcin

Publication type:

Article

Regulation of tristetraprolin expression by mitogen-activated protein kinase phosphatase-1.

Published in:

APMIS, 2012, v. 120, n. 12, p. 988, doi. 10.1111/j.1600-0463.2012.02927.x

By:

Huotari, Noora;
Hömmö, Tuija;
Taimi, Ville;
Nieminen, Riina;
Moilanen, Eeva;
Korhonen, Riku

Publication type:

Article

MKP-1 overexpression is associated with chemoresistance in bladder cancer via the MAPK pathway.

Published in:

Oncology Letters, 2020, v. 20, n. 2, p. 1743, doi. 10.3892/ol.2020.11741

By:

Lei, Siyu;
Xu, Hong;
Chen, Naiwen;
Pan, Huan;
Xie, Wenhua;
He, Yi;
Jin, Jing

Publication type:

Article

A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29673-y

By:

Wang, Huanchen;
Perera, Lalith;
Jork, Nikolaus;
Zong, Guangning;
Riley, Andrew M.;
Potter, Barry V. L.;
Jessen, Henning J.;
Shears, Stephen B.

Publication type:

Article

Osmotic-Adaptation Response of sakA/hogA Gene to Aflatoxin Biosynthesis, Morphology Development and Pathogenicity in Aspergillus flavus.

Published in:

Toxins, 2019, v. 11, n. 1, p. 41, doi. 10.3390/toxins11010041

By:

Tumukunde, Elisabeth;
Li, Ding;
Qin, Ling;
Li, Yu;
Shen, Jiaojiao;
Wang, Shihua;
Yuan, Jun

Publication type:

Article

The Pore-Forming α-Toxin from Clostridium septicum Activates the MAPK Pathway in a Ras-c-Raf-Dependent and Independent Manner.

Published in:

Toxins, 2015, v. 7, n. 2, p. 516, doi. 10.3390/toxins7020516

By:

Chakravorty, Anjana;
Awad, Milena M.;
Cheung, Jackie K.;
Hiscox, Thomas J.;
Lyras, Dena;
Rood, Julian I.

Publication type:

Article

Genetic interactions of ribosome maturation factors Yvh1 and Mrt4 influence mRNA decay, glycogen accumulation, and the expression of early meiotic genes in Saccharomyces cerevisiae.

Published in:

Journal of Biochemistry, 2011, v. 150, n. 1, p. 103, doi. 10.1093/jb/mvr040

By:

Sugiyama, Minetaka;
Nugroho, Satya;
Iida, Naoko;
Sakai, Taiki;
Kaneko, Yoshinobu;
Harashima, Satoshi

Publication type:

Article

Regulation of IGF-1/PI3K/Akt signalling by the phosphoinositide phosphatase pharbin.

Published in:

Journal of Biochemistry, 2011, v. 150, n. 1, p. 83, doi. 10.1093/jb/mvr037

By:

Wang, Feng;
Ijuin, Takeshi;
Itoh, Toshiki;
Takenawa, Tadaomi

Publication type:

Article

Rosiglitazone Improves Glucocorticoid Resistance in a Sudden Sensorineural Hearing Loss by Promoting MAP Kinase Phosphatase-1 Expression.

Published in:

Mediators of Inflammation, 2019, p. 1, doi. 10.1155/2019/7915730

By:

Xia, Liang;
Liu, Jingjing;
Sun, Yuanyuan;
Shi, Haibo;
Yang, Guang;
Feng, Yanmei;
Yin, Shankai

Publication type:

Article

Pharmacological Inhibition of ERK Signaling Rescues Pathophysiology and Behavioral Phenotype Associated with 16p11.2 Chromosomal Deletion in Mice.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 30, p. 6640, doi. 10.1523/JNEUROSCI.0515-17.2018

By:

Pucilowska, Joanna;
Vithayathil, Joseph;
Pagani, Marco;
Kelly, Caitlin;
Karlo, J. Colleen;
Robol, Camilla;
Morelia, Ilaria;
Gozzi, Alessandro;
Brambilla, Riccardo;
Landreth, Gary E.

Publication type:

Article

Speaker's Abstract Lectures.

Published in:: Clinical Science, 2024, v. 138, p. A2, doi. 10.1042/CS2023ET18
Publication type:: Article

VEGFR2 mediated RAS/MAPK signaling pathway to explore the mechanism of Bushen Antai Granule in the treatment of recurrent abortion.

Published in:

Journal of Hainan Medical University, 2021, v. 27, n. 9, p. 30

By:

Wei Chang;
Wei-Li Li;
Sha-Sha Lu

Publication type:

Article

mRNA Metabolism in Health and Disease.

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2262, doi. 10.3390/biomedicines10092262

By:

Romão, Luísa

Publication type:

Article

UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway.

Published in:

Biomedicines, 2022, v. 10, n. 4, p. 793, doi. 10.3390/biomedicines10040793

By:

Lee, Suman;
Hwang, Yukyung;
Kim, Tae Hun;
Jeong, Jaemin;
Choi, Dongho;
Hwang, Jungwook

Publication type:

Article

Convergent ERK1/2, p38 and JNK mitogen activated protein kinases (MAPKs) signalling mediate catecholoestradiol-induced proliferation of ovine uterine artery endothelial cells.

Published in:

Journal of Physiology, 2017, v. 595, n. 14, p. 4663, doi. 10.1113/JP274119

By:

Landeros, Rosalina Villalon;
Jobe, Sheikh O.;
Aranda‐Pino, Gabrielle;
Lopez, Gladys E.;
Zheng, Jing;
Magness, Ronald R.

Publication type:

Article

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress.

Published in:

Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.796812

By:

Shen, Lei;
Zhou, Kaige;
Liu, Hong;
Yang, Jie;
Huang, Shuqi;
Yu, Fei;
Huang, Dongya

Publication type:

Article

Prediction of Mechanosensitive Genes in Vascular Endothelial Cells Under High Wall Shear Stress.

Published in:

Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.796812

By:

Shen, Lei;
Zhou, Kaige;
Liu, Hong;
Yang, Jie;
Huang, Shuqi;
Yu, Fei;
Huang, Dongya

Publication type:

Article

miRNA limits MAP kinase-mediated immunity: optimization of plant fitness.

Published in:

Journal of Experimental Botany, 2017, v. 68, n. 21/22, p. 5685, doi. 10.1093/jxb/erx385

By:

Shengjun Li;
Bin Yu

Publication type:

Article

B-Raf and the inhibitors: from bench to bedside.

Published in:

Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8722-6-30

By:

Tiangui Huang;
Karsy, Michael;
Jian Zhuge;
Minghao Zhong;
Delong Liu

Publication type:

Article

Dual Specificity Phosphatase 1 Regulates Human Inducible Nitric Oxide Synthase Expression by p38 MAP Kinase.

Published in:

Mediators of Inflammation, 2011, v. 2011, p. 1, doi. 10.1155/2011/127587

By:

Turpeinen, Tuija;
Nieminen, Riina;
Taimi, Ville;
Heittola, Taina;
Sareila, Outi;
Clark, Andrew R.;
Moilanen, Eeva;
Korhonen, Riku

Publication type:

Article

Astaxanthin Attenuates Environmental Tobacco Smoke-Induced Cognitive Deficits: A Critical Role of p38 MAPK.

Published in:

Marine Drugs, 2019, v. 17, n. 1, p. 24, doi. 10.3390/md17010024

By:

Yang, Xia;
Guo, An-Lei;
Pang, Yi-Peng;
Cheng, Xiao-Jing;
Xu, Ting;
Li, Xin-Rui;
Liu, Jiao;
Zhang, Yu-Yun;
Liu, Yi

Publication type:

Article

JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component.

Published in:

Molecular Cancer, 2017, v. 16, p. 1, doi. 10.1186/s12943-017-0744-2

By:

Xujun Liu;
Wenzhe Si;
Xinhua Liu;
Lin He;
Jie Ren;
Ziran Yang;
Jianguo Yang;
Wanjin Li;
Shumeng Liu;
Fei Pei;
Xiaohan Yang;
Luyang Sun

Publication type:

Article

Nutritional plane of twin-bearing ewes alters fetal mammary gland biochemical composition and mTOR/MAPK pathway signaling.

Published in:

Journal of Animal Science, 2015, v. 93, n. 2, p. 699, doi. 10.2527/jas.2014-8394

By:

Sciascia, Q.;
Sales, F.;
van der Linden, D.;
Wards, N.;
Oliver, M.;
Blair, H;
McCoard, S.

Publication type:

Article

The role of deubiquitinases in cardiac disease.

Published in:: Expert Reviews in Molecular Medicine, 2024, v. 26, p. 1, doi. 10.1017/erm.2024.2
Publication type:: Article

Tumor necrosis factor α-induced protein 8-like 1 promotes apoptosis by regulating B-cell leukemia/lymphoma-2 family proteins in RAW264.7 cells.

Published in:

Oncology Letters, 2016, v. 12, n. 5, p. 3506, doi. 10.3892/ol.2016.5090

By:

YINAN WANG;
YAO LIU;
CHUNFANG HU;
XIAOYAN NI;
XIAOBO HUANG

Publication type:

Article

Eupatilin induces human renal cancer cell apoptosis via ROS-mediated MAPK and PI3K/AKT signaling pathways.

Published in:

Oncology Letters, 2016, v. 12, n. 4, p. 2894, doi. 10.3892/ol.2016.4989

By:

WEI-FENG ZHONG;
XIAO-HONG WANG;
BIN PAN;
FENG LI;
LU KUANG;
ZE-XUAN SU

Publication type:

Article

Ulinastatin attenuates diabetes-induced cardiac dysfunction by the inhibition of inflammation and apoptosis.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 3, p. 2497, doi. 10.3892/etm.2017.4824

By:

WEN-KE WANG;
QING-HUA LU;
XIN WANG;
BEN WANG;
JUAN WANG;
HUI-PING GONG;
LIN WANG;
HAO LI;
YI-MENG DU

Publication type:

Article

Astrocyte ERK phosphorylation precedes K.

Published in:

Neuropathology, 2011, v. 31, n. 3, p. 250, doi. 10.1111/j.1440-1789.2010.01172.x

By:

Liping Cai;
Ting Du;
Dan Song;
Baoman Li;
Hertz, Leif;
Liang Peng

Publication type:

Article

Arabidopsis MAP kinase phosphatase 1 and its target MAP kinases 3 and 6 antagonistically determine UV-B stress tolerance, independent of the UVR8 photoreceptor pathway.

Published in:

Plant Journal, 2011, v. 68, n. 4, p. 727, doi. 10.1111/j.1365-313X.2011.04725.x

By:

Besteiro, Marina A. González;
Bartels, Sebastian;
Albert, Andreas;
Ulm, Roman

Publication type:

Article

Pleiotropic effects of cancer cells' secreted factors on human stromal (mesenchymal) stem cells.

Published in:

Stem Cell Research & Therapy, 2013, v. 4, n. 5, p. 1, doi. 10.1186/scrt325

By:

Al-toub, Mashael;
Almusa, Abdulaziz;
Almajed, Mohammed;
Al-Nbaheen, May;
Kassem, Moustapha;
Aldahmash, Abdullah;
Alajez, Nehad M.

Publication type:

Article

p38δ MAPK: Emerging Roles of a Neglected Isoform.

Published in:

International Journal of Cell Biology, 2014, p. 1, doi. 10.1155/2014/272689

By:

O'Callaghan, Carol;
Fanning, Liam J.;
Barry, Orla P.

Publication type:

Article

Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.

Published in:

European Journal of Human Genetics, 2015, v. 23, n. 11, p. 1482, doi. 10.1038/ejhg.2015.29

By:

Bronicki, Lucas M;
Redin, Claire;
Drunat, Severine;
Piton, Amélie;
Lyons, Michael;
Passemard, Sandrine;
Baumann, Clarisse;
Faivre, Laurence;
Thevenon, Julien;
Rivière, Jean-Baptiste;
Isidor, Bertrand;
Gan, Grace;
Francannet, Christine;
Willems, Marjolaine;
Gunel, Murat;
Jones, Julie R;
Gleeson, Joseph G;
Mandel, Jean-Louis;
Stevenson, Roger E;
Friez, Michael J

Publication type:

Article