Results
Title

Inflammatory augmentation of the delayed type hypersensitivity arthritis mouse model.

Authors

Tønnessen, Theis Christian; Ueland, Thor; Ahmed, Muhammad Shakil; Attramadal, Håvard; Sjaastad, Ivar; Vinge, Leif Erik

Abstract

2012; 14 (3): R134. doi: 10.1186/ar3867 5 Atkinson SM, Nansen A. Pharmacological value of murine delayed-type hypersensitivity arthritis: a robust mouse model of rheumatoid arthritis in C57BL/6 mice. As blood sampling could only be performed once a week, mice in each intervention group were randomized to either blood sampling just before mBSA injection (baseline) or blood sampling 24 h after mBSA injections (at assumed peak inflammation). Keywords: animal models; arthritis; inflammation; mouse model; rheumatoid arthritis EN animal models arthritis inflammation mouse model rheumatoid arthritis 551 555 5 05/15/23 20230601 NES 230601 INTRODUCTION AND BACKGROUND Rheumatoid arthritis (RA) is the most prevalent autoimmune disease with an incidence of about 0.5%-1% of the general population.[1] Several experimental mouse models mimicking RA exist.[2] All these models harbour various experimental features ranging from specific pathophysiological mechanisms, as well as degree and durability of inflammation. Animal models, arthritis, inflammation, mouse model, rheumatoid arthritis.

Subjects

DELAYED hypersensitivity; LABORATORY mice; ANIMAL disease models; ARTHRITIS; EXPERIMENTAL arthritis; IMMUNOGLOBULINS

Publication

Basic & Clinical Pharmacology & Toxicology, 2023, Vol 132, Issue 6, p551

ISSN

1742-7835

Publication type

Academic Journal

DOI

10.1111/bcpt.13864