Works matching IS 17501326 AND DT 2010 AND VI 5

Results: 61

A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 52, doi. 10.1186/1750-1326-5-52

By:

Wang, Lina;
Brown, Anthony

Publication type:

Article

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 47, doi. 10.1186/1750-1326-5-47

By:

Khandelwal, Preeti J.;
Dumanis, Sonya B.;
Feng, Li Rebekah;
Maguire-Zeiss, Kathleen;
Rebeck, G. W.;
Lashuel, Hilal A.;
Moussa, Charbel E. H.

Publication type:

Article

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 61, doi. 10.1186/1750-1326-5-61

By:

Gersbacher, Manuel T.;
Doo Yeon Kim;
Bhattacharyya, Raja;
Kovacs, Dora M.

Publication type:

Article

DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 60, doi. 10.1186/1750-1326-5-60

By:

Jianmin Chen;
Cohen, Mark L.;
Lerner, Alan J.;
Yan Yang;
Herrup, Karl

Publication type:

Article

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 58, doi. 10.1186/1750-1326-5-58

By:

Kegel, Kimberly B.;
Sapp, Ellen;
Alexander, Jonathan;
Reeves, Patrick;
Bleckmann, Dorothee;
Sobin, Linsday;
Masso, Nicholas;
Valencia, Antonio;
Jeong, Hyunkyung;
Krainc, Dimitri;
Palacino, James;
Curtis, Daniel;
Kuhn, Rainer;
Betschart, Claudia;
Sena-Esteves, Miguel;
Aronin, Neil;
Paganetti, Paolo;
DiFiglia, Marian

Publication type:

Article

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 57, doi. 10.1186/1750-1326-5-57

By:

Kayed, Rakez;
Canto, Isabel;
Breydo, Leonid;
Rasool, Suhail;
Lukacsovich, Tamas;
Wu, Jessica;
III, Ricardo Albay;
Pensalfini, Anna;
Yeung, Stephen;
Head, Elizabeth;
Marsh, J. Lawrence;
Glabe, Charles

Publication type:

Article

Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal cultureand Caenorhabditis elegans.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 59, doi. 10.1186/1750-1326-5-59

By:

Keowkase, Roongpetch;
Aboukhatwa, Marwa;
Bao-Ling Adam;
Beach, J. Warren;
Terry, Jr, Alvin V.;
Buccafussco, Jerry J.;
Yuan Luo

Publication type:

Article

ER stress response plays an important role inaggregation of -α-synuclein.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 56, doi. 10.1186/1750-1326-5-56

By:

Peizhou Jiang;
Ming Gan;
Ebrahim, Abdul Shukkur;
Wen-Lang Lin;
Melrose, Heather L.;
Yen, Shu-Hui C.

Publication type:

Article

α-synuclein induced synapse damage is enhanced by amyloid-β1-42.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 55, doi. 10.1186/1750-1326-5-55

By:

Bate, Clive;
Gentleman, Steve;
Williams, Alun

Publication type:

Article

ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 54, doi. 10.1186/1750-1326-5-54

By:

Shuchen Lee;
Guang Yang;
Yue Yong;
Ying Liu;
Liyun Zhao;
Jing Xu;
Xiaomin Zhang;
Yanjie Wan;
Chun Feng;
Zhiqin Fan;
Yong Liu;
Jia Luo;
Zun-Ji Ke

Publication type:

Article

Age-related synaptic loss of the medial olivocochlear efferent innervation.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 53, doi. 10.1186/1750-1326-5-53

By:

Benjamin Fu;
Le Prell, Colleen;
Dwayne Simmons;
Debin Lei;
Angela Schrader;
Chen, Amelia B.;
Jianxin Bao

Publication type:

Article

Aminopeptidases do not directly degrade tau protein.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 48, doi. 10.1186/1750-1326-5-48

By:

Chow, K. Martin;
Guan, Hanjun;
Hersh, Louis B.

Publication type:

Article

Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 51, doi. 10.1186/1750-1326-5-51

By:

Caccamo, Antonella;
Magrí, Andrea;
Oddo, Salvatore

Publication type:

Article

Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 50, doi. 10.1186/1750-1326-5-50

By:

Barbeito, Ana G.;
Levade, Thierry;
Delisle, Marie B.;
Ghetti, Bernardino;
Vidal, Ruben

Publication type:

Article

NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 49, doi. 10.1186/1750-1326-5-49

By:

Young-Don Kwak;
Tao Ma;
Shiyong Diao;
Xue Zhang;
Yaomin Chen;
Janet Hsu;
Lipton, Stuart A.;
Masliah, Eliezer;
Huaxi Xu;
Francesca-Fang Liao

Publication type:

Article

Fcϒ receptors are required for NF-κB signaling, microglial activation and dopaminergic neurodegeneration in an AAV-synuclein mouse model of Parkinson¿s disease.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 42, doi. 10.1186/1750-1326-5-42

By:

Cao, Shuwen;
Theodore, Shaji;
Standaert, David G.

Publication type:

Article

Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 46, doi. 10.1186/1750-1326-5-46

By:

Xu Wang;
Wei Zheng;
Jing-Wei Xie;
Tao Wang;
Si-Ling Wang;
Wei-Ping Teng;
Zhan-You Wang

Publication type:

Article

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 45, doi. 10.1186/1750-1326-5-45

By:

O'Leary, III., John C.;
Qingyou Li;
Marinec, Paul;
Blair, Laura J.;
Congdon, Erin E.;
Johnson, Amelia G.;
Jinwal, Umesh K.;
Koren, III., John;
Jones, Jeffrey R.;
Kraft, Clara;
Peters, Melinda;
Abisambra, Jose F.;
Duff, Karen E.;
Weeber, Edwin J.;
Gestwicki, Jason E.;
Dickey, Chad A.

Publication type:

Article

Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-β peptides in the cerebral spinal fluid of rats.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 44, doi. 10.1186/1750-1326-5-44

By:

Suon, Sokreine;
Jie Zhao;
Villarreal, Stephanie A.;
Anumula, Nikesh;
Mali Liu;
Carangia, Linda M.;
Renger, John J.;
Zerbinatti, Celina V.

Publication type:

Article

MOLECULAR NEURODEGENERATION.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 43, doi. 10.1186/1750-1326-5-43

By:

Koprich, James B.;
Johnston, Tom H.;
Reyes, M. Gabriela;
Xuan Sun;
Brotchie, Jonathan M.

Publication type:

Article

Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survivalmotor neuron 1.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 41, doi. 10.1186/1750-1326-5-41

By:

Chitramuthu, Babykumari P.;
Baranowski, David C.;
Kay, Denis G.;
Bateman, Andrew;
Bennett, Hugh P. J.

Publication type:

Article

Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent andretromer-mediated.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 40, doi. 10.1186/1750-1326-5-40

By:

Vieira, Sandra I.;
Rebelo, Sandra;
Esselmann, Hermann;
Wiltfang, Jens;
Lah, James;
Lane, Rachel;
Small, Scott A.;
Gandy, Sam;
da Cruz e Silva, Edgar F.;
da Cruz e Silva, Odete A. B.

Publication type:

Article

The biochemical aftermath of anti-amyloid immunotherapy.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 39, doi. 10.1186/1750-1326-5-39

By:

Maarouf, Chera L.;
Daugs, Ian D.;
Kokjohn, Tyler A.;
Kalback, Walter M.;
Patton, R. Lyle;
Luehrs, Dean C.;
Masliah, Eliezer;
Nicoll, James A. R.;
Sabbagh, Marwan N.;
Beach, Thomas G.;
Castaño, Eduardo M.;
Roher, Alex E.

Publication type:

Article

Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 38, doi. 10.1186/1750-1326-5-38

By:

De Gasperi, Rita;
Gama Sosa, Miguel A.;
Dracheva, Stella;
Elder, Gregory A.

Publication type:

Article

BACE1 gene variants do not influence BACE1 activity, levels of APP or AΒ isoforms in CSF in Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 37, doi. 10.1186/1750-1326-5-37

By:

Sjölander, Annica;
Zetterberg, Henrik;
Andreasson, Ulf;
Minthon, Lennart;
Blennow, Kaj

Publication type:

Article

Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 36, doi. 10.1186/1750-1326-5-36

By:

Akram, Afia;
Schmeidler, James;
Katsel, Pavel;
Hof, Patrick R.;
Haroutunian, Vahram

Publication type:

Article

Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 35, doi. 10.1186/1750-1326-5-35

By:

Kondo, Maho;
Shiono, Maki;
Itoh, Genzo;
Takei, Norio;
Matsushima, Takahide;
Maeda, Masahiro;
Taru, Hidenori;
Hata, Saori;
Yamamoto, Tohru;
Saito, Yuhki;
Suzuki, Toshiharu

Publication type:

Article

Isoform of APOE with retained intron 3; quantitation and identification of an associated single nucleotide polymorphism.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 34, doi. 10.1186/1750-1326-5-34

By:

Dieter, Laura S.;
Estus, Steven

Publication type:

Article

Phosphorylation regulates proteasomal-mediated degradation and solubility of TAR DNA binding protein-43 C-terminal fragments.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 33, doi. 10.1186/1750-1326-5-33

By:

Yong-Jie Zhang;
Gendron, Tania F.;
Ya-Fei Xu;
Li-Wen Ko;
Shu-Hui Yen;
Petrucelli, Leonard

Publication type:

Article

Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 32, doi. 10.1186/1750-1326-5-32

By:

Winkler, Ethan A.;
Bell, Robert D.;
Zlokovic, Berislav V.

Publication type:

Article

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 31, doi. 10.1186/1750-1326-5-31

By:

Hitt, Brian D.;
Jaramillo, Thomas C.;
Chetkovich, Dane M.;
Vassar, Robert

Publication type:

Article

Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K+ and Ca2+ homeostasis.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 30, doi. 10.1186/1750-1326-5-30

By:

Shabala, Lana;
Howells, Claire;
West, Adrian K.;
Chung, Roger S.

Publication type:

Article

Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 29, doi. 10.1186/1750-1326-5-29

By:

Didonna, Alessandro;
Legname, Giuseppe

Publication type:

Article

No dramatic age-related loss of hair cells and spiral ganglion neurons in Bcl-2 over-expression mice or Bax null mice.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 28, doi. 10.1186/1750-1326-5-28

By:

Haiyan Shen;
Matsui, Jonathan I.;
Debin Lei;
Lirong Han;
Ohlemiller, Kevin K.;
Jianxin Bao

Publication type:

Article

First evidence of overlaps between HIV-Associated Dementia (HAD) and non-viral neurodegenerative diseases: proteomic analysis of the frontal cortex from HIV+ patients with and without dementia.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 27, doi. 10.1186/1750-1326-5-27

By:

Li Zhou;
Diefenbach, Eve;
Crossett, Ben;
Tran, Sieu L.;
Ng, Thomas;
Rizos, Helen;
Rua, Rejane;
Bin Wang;
Kapur, Amit;
Gandhi, Kaushal;
Brew, Bruce J.;
Saksena, Nitin K.

Publication type:

Article

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 26, doi. 10.1186/1750-1326-5-26

By:

Fox, Jonathan H.;
Connor, Teal;
Chopra, Vanita;
Dorsey, Kate;
Kama, Jibrin A.;
Bleckmann, Dorothee;
Betschart, Claudia;
Hoyer, Daniel;
Frentzel, Stefan;
DiFiglia, Marian;
Paganetti, Paolo;
Hersch, Steven M.

Publication type:

Article

Heat shock protein 90 in neurodegenerative diseases.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 24, doi. 10.1186/1750-1326-5-24

By:

Wenjie Luo;
Weilin Sun;
Taldone, Tony;
Rodina, Anna;
Chiosis, Gabriela

Publication type:

Article

Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 25, doi. 10.1186/1750-1326-5-25

By:

Fuhrmann, Nico;
Schimpf, Simone;
Kamenisch, York;
Leo-Kottler, Beate;
Alexander, Christiane;
Auburger, Georg;
Zrenner, Eberhart;
Wissinger, Bernd;
Alavi, Marcel V.

Publication type:

Article

Effect of Apolipoprotein E ε4 on the association between health behaviors and cognitive function in late midlife.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 23, doi. 10.1186/1750-1326-5-23

By:

Sabia, Séverine;
Kivimaki, Mika;
Kumari, Meena;
Shipley, Martin J.;
Singh-Manoux, Archana

Publication type:

Article

Localization of BDNF mRNA with the Huntington's disease protein in rat brain.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 22, doi. 10.1186/1750-1326-5-22

By:

Bin Ma;
Culver, Brady P.;
Baj, Gabriele;
Tongiorgi, Enrico;
Chao, Moses V.;
Tanese, Naoko

Publication type:

Article

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 21, doi. 10.1186/1750-1326-5-21

By:

Keeney, Paula M.;
Bennett, Jr, James P.

Publication type:

Article

The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 20, doi. 10.1186/1750-1326-5-20

By:

Kim, Jihoon;
Harada, Ryuichi;
Kobayashi, Masaki;
Kobayashi, Natsuki;
Sode, Koji

Publication type:

Article

Endocytic pathways mediating oligomeric AΒ42 neurotoxicity.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 19, doi. 10.1186/1750-1326-5-19

By:

Chunjiang Yu;
Nwabuisi-Heath, Evelyn;
Laxton, Kevin;
Mary Jo LaDu

Publication type:

Article

ApoE mimetic peptide decreases AΒ production in vitro and in vivo.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 16, doi. 10.1186/1750-1326-5-16

By:

Minami, S. Sakura;
Cordova, Antoinette;
Cirrito, John R.;
Tesoriero, Joseph A.;
Babus, Lenard W.;
Davis, Gary C.;
Dakshanamurthy, Sivanesan;
Turner, R. Scott;
Pak, Daniel T. S.;
Rebeck, G. William;
Paige, Mikell;
Hyang-Sook Hoe

Publication type:

Article

Tetrabenazine is neuroprotective in Huntington's disease mice.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 18, doi. 10.1186/1750-1326-5-18

By:

Hongyu Wang;
Xi Chen;
Yuemei Li;
Tie-Shan Tang;
Bezprozvanny, Ilya

Publication type:

Article

High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 17, doi. 10.1186/1750-1326-5-17

By:

Fallini, Claudia;
Bassell, Gary J.;
Rossoll, Wilfried

Publication type:

Article

Soluble amyloid-β, effect on cerebral arteriolar regulation and vascular cells.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 15, doi. 10.1186/1750-1326-5-15

By:

Dietrich, Hans H.;
Chuanxi Xiang;
Han, Byung H.;
Zipfel, Gregory J.;
Holtzman, David M.

Publication type:

Article

Lysosomal function in macromolecular homeostatis and bioenergetics in Parkinson's disease.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 14, doi. 10.1186/1750-1326-5-14

By:

Schneider, Lonnie;
Jianhua Zhang

Publication type:

Article

Phospholipase A2 inhibitors protect against prion and Aβ mediated synapse degeneration.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 13, doi. 10.1186/1750-1326-5-13

By:

Bate, Clive;
Tayebi, Mourad;
Williams, Alun

Publication type:

Article

Microglia in the aging brain: relevance to neurodegeneration.

Published in:

Molecular Neurodegeneration, 2010, v. 5, p. 12, doi. 10.1186/1750-1326-5-12

By:

Xiao-Guang Luo;
Jian-Qing Ding;
Sheng-Di Chen

Publication type:

Article