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- Title
CYP1A2 polymorphism -1545C > T (rs2470890) is associated with increased side effects to clozapine.
- Authors
Viikki, Merja; Kampman, Olli; Seppälä, Niko; Mononen, Nina; Lehtimäki, Terho; Leinonen, Esa
- Abstract
Cytochrome P450 1A2 gene (CYP1A2) polymorphisms have been suggested to be associated with increased side effects to antipsychotics. However, studies on this are scarce and have been conducted with either various antipsychotics or only in small samples of patients receiving clozapine. The aim of the present study was to test for an association between the CYP1A2 -1545C > T (rs2470890) polymorphism and side effects in a larger sample of patients during long-term clozapine treatment.
- Publication
BMC psychiatry, 2014, Vol 14, p50
- ISSN
1471-244X
- Publication type
Journal Article
- DOI
10.1186/1471-244X-14-50