Works matching DE "BIOCHEMICAL mechanism of action"

Results: 3643

Promoter melting by an alternative σ, one base at a time.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 350, doi. 10.1038/nsmb.2798

By:

Darst, Seth A;
Feklistov, Andrey;
Gross, Carol A

Publication type:

Article

Mechanism of IRSp53 inhibition and combinatorial activation by Cdc42 and downstream effectors.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 413, doi. 10.1038/nsmb.2781

By:

Kast, David J;
Yang, Changsong;
Disanza, Andrea;
Boczkowska, Malgorzata;
Madasu, Yadaiah;
Scita, Giorgio;
Svitkina, Tatyana;
Dominguez, Roberto

Publication type:

Article

New insights into ubiquitin E3 ligase mechanism.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 301, doi. 10.1038/nsmb.2780

By:

Berndsen, Christopher E;
Wolberger, Cynthia

Publication type:

Article

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 366, doi. 10.1038/nsmb.2796

By:

Aymard, François;
Bugler, Beatrix;
Schmidt, Christine K;
Guillou, Emmanuelle;
Caron, Pierre;
Briois, Sébastien;
Iacovoni, Jason S;
Daburon, Virginie;
Miller, Kyle M;
Jackson, Stephen P;
Legube, Gaëlle

Publication type:

Article

Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 308, doi. 10.1038/nsmb.2792

By:

Mattiroli, Francesca;
Sixma, Titia K

Publication type:

Article

The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 3, p. 318, doi. 10.1038/nsmb.1562

By:

Friel, Claire T.;
Smith, D. Alastair;
Vendruscolo, Michele;
Gsponer, Joerg;
Radford, Sheena E.

Publication type:

Article

Leflunomide: A novel disease modifying Leflunomide: A novel disease modifying anti-rheumatic drug.

Published in:

Journal of Postgraduate Medicine, 2004, v. 50, n. 2, p. 154

By:

Kale, V.P.;
Bichile, L.S.

Publication type:

Article

Levetiracetam en crisis convulsivas refractarias de inicio en la etapa neonatal: Experiencia en el Instituto Nacional de Perinatología.

Published in:

Revista Mexicana de Neurociencia, 2010, v. 11, n. 3, p. 199

By:

Ríos Flores, Braulio A.;
Puig, Jorge Ibarra;
Piña, Efraín Olivas;
Baez, Leticia Munive

Publication type:

Article

Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease.

Published in:

Redox Report, 2010, v. 15, n. 4, p. 185, doi. 10.1179/174329210X12650506623528

By:

Francisco, Amanda Fortes;
De Abreu Vieira, Paula Melo;
Arantes, Jerusa Marilda;
Silva, Maisa;
Pedrosa, Maria Lúcia;
Elói-Santos, Silvana Maria;
Martins-Filho, Olindo Assis;
Teixeira-Carvalho, Andréa;
Araújo, M´rcio Sobreira Silva;
Tafuri, Washington Luiz;
Carneiro, Cláudia Martins

Publication type:

Article

Antioxidant properties of Plumbago zeylanica, an Indian medicinal plant and its active ingredient, plumbagin.

Published in:

Redox Report, 2004, v. 9, n. 4, p. 219, doi. 10.1179/135100004225005976

By:

Tilak, Jai C.;
Adhikari, Soumyakanti;
Devasagayam, Thomas P. A.

Publication type:

Article

Antioxidant properties of phenolic Schiff bases: structure–activity relationship and mechanism of action.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 11, p. 951, doi. 10.1007/s10822-013-9692-0

By:

Anouar, El Hassane;
Raweh, Salwa;
Bayach, Imene;
Taha, Muhammad;
Baharudin, Mohd Syukri;
Di Meo, Florent;
Hasan, Mizaton Hazizul;
Adam, Aishah;
Ismail, Nor Hadiani;
Weber, Jean-Frédéric F.;
Trouillas, Patrick

Publication type:

Article

Immunotherapies for pediatric cancer: current landscape and future perspectives.

Published in:

Cancer & Metastasis Reviews, 2019, v. 38, n. 4, p. 573, doi. 10.1007/s10555-019-09819-z

By:

Hutzen, Brian;
Paudel, Siddhi Nath;
Naeimi Kararoudi, Meisam;
Cassady, Kevin A.;
Lee, Dean A.;
Cripe, Timothy P.

Publication type:

Article

It is not just the drugs that matter: the nocebo effect.

Published in:

Cancer & Metastasis Reviews, 2019, v. 38, n. 1/2, p. 315, doi. 10.1007/s10555-019-09800-w

By:

Wojtukiewicz, Marek Z.;
Politynska, Barbara;
Skalij, Piotr;
Tokajuk, Piotr;
Wojtukiewicz, Anna M.;
Honn, Kenneth V.

Publication type:

Article

Experience with Levosimendan in 32 Paediatric Patients.

Published in:

Pediatric Cardiology, 2015, v. 36, n. 5, p. 1038, doi. 10.1007/s00246-015-1117-5

By:

Vilaboa Pedrosa, Clara;
Martínez Roca, Cristina;
Yáñez Gómez, Pedro;
Martín Herranz, María

Publication type:

Article

Novel applications of mass spectrometry‐based metabolomics in herbal medicines and its active ingredients: Current evidence.

Published in:

Mass Spectrometry Reviews, 2019, v. 38, n. 4/5, p. 380, doi. 10.1002/mas.21589

By:

Wang, Xi‐Jun;
Ren, Jun‐Ling;
Zhang, Ai‐Hua;
Sun, Hui;
Yan, Guang‐Li;
Han, Ying;
Liu, Liang

Publication type:

Article

Modification of cysteine residues by cyclopentenone prostaglandins: Interplay with redox regulation of protein function.

Published in:

Mass Spectrometry Reviews, 2014, v. 33, n. 2, p. 110, doi. 10.1002/mas.21383

By:

Oeste, Clara L.;
Pérez-Sala, Dolores

Publication type:

Article

Aspirin and Clopidogrel: Efficacy, Treatment, and Resistance in Coronary Artery Disease.

Published in:

International Journal of Angiology (Springer Science & Business Media B.V.), 2005, v. 14, n. 3, p. 109, doi. 10.1055/s-0031-1276498

By:

Maksoud, Aziz;
Candipan, Robert C.;
Wilson, David B.;
Vacek, James L.

Publication type:

Article

WNT16 Requires Gα Subunits as Intracellular Partners for Both Its Canonical and Non-Canonical WNT Signalling Activity in Osteoblasts.

Published in:

2020

By:

Hendrickx, Gretl;
Boudin, Eveline;
Verbeek, Marinus;
Fransen, Erik;
Mortier, Geert;
Van Hul, Wim

Publication type:

journal article

Icariin Stimulates Differentiation and Suppresses Adipocytic Transdifferentiation of Primary Osteoblasts Through Estrogen Receptor-Mediated Pathway.

Published in:

2016

By:

Zhang, Dawei;
Fong, Chichun;
Jia, Zhenbin;
Cui, Liao;
Yao, Xinsheng;
Yang, Mengsu

Publication type:

journal article

In Vitro and In Vivo Responses to High and Low Doses of Nitrogen-Containing Bisphosphonates Suggest Engagement of Different Mechanisms for Inhibition of Osteoclastic Bone Resorption.

Published in:

Calcified Tissue International, 2013, v. 92, n. 6, p. 531, doi. 10.1007/s00223-013-9711-0

By:

Fisher, John;
Rosenberg, Elizabeth;
Santora, Arthur;
Reszka, Alfred

Publication type:

Article

Calcium signals and FGF-2 induced neurite growth in cultured parasympathetic neurons: spatial localization and mechanisms of activation.

Published in:

Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 9, p. 1355, doi. 10.1007/s00424-013-1257-5

By:

Zamburlin, P.;
Ruffinatti, F.;
Gilardino, A.;
Farcito, S.;
Parrini, M.;
Lovisolo, Davide

Publication type:

Article

The sleep relay-the role of the thalamus in central and decentral sleep regulation.

Published in:

Pflügers Archiv: European Journal of Physiology, 2012, v. 463, n. 1, p. 53, doi. 10.1007/s00424-011-1014-6

By:

Coulon, Philippe;
Budde, Thomas;
Pape, Hans-Christian

Publication type:

Article

Mechanism of the NMDA-receptor mediated vasodilation induced by glutamate in vascular smooth muscle.

Published in:: 2000
Publication type:: Abstract

A comprehensive analysis to understand the mechanism of action of balneotherapy: why, how, and where they can be used? Evidence from in vitro studies performed on human and animal samples.

Published in:

International Journal of Biometeorology, 2020, v. 64, n. 7, p. 1247, doi. 10.1007/s00484-020-01890-4

By:

Cheleschi, Sara;
Gallo, Ines;
Tenti, Sara

Publication type:

Article

Controversies about the subcellular localization and mechanisms of action of the Alzheimer's disease-protective CD33 splice variant.

Published in:

2019

By:

Saha, Sudeshna;
Siddiqui, Shoib S.;
Khan, Naazneen;
Verhagen, Andrea;
Jiang, Weiping;
Springer, Stevan;
Ghosh, Pradipta;
Varki, Ajit

Publication type:

Letter

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma.

Published in:

Acta Neuropathologica, 2011, v. 121, n. 6, p. 763, doi. 10.1007/s00401-011-0817-z

By:

Cin, Huriye;
Meyer, Claus;
Herr, Ricarda;
Janzarik, Wibke;
Lambert, Sally;
Jones, David;
Jacob, Karine;
Benner, Axel;
Witt, Hendrik;
Remke, Marc;
Bender, Sebastian;
Falkenstein, Fabian;
Anh, Ton;
Olbrich, Heike;
Deimling, Andreas;
Pekrun, Arnulf;
Kulozik, Andreas;
Gnekow, Astrid;
Scheurlen, Wolfram;
Witt, Olaf

Publication type:

Article

Exploring the First FDA-Approved Treatment to Delay T1D Onset: Mechanism of Action and Treatment Impact.

Published in:

Patient Care (Online), 2024, p. 1

By:

Goldman, Jennifer D.

Publication type:

Article

Survodutide, Dual Glucagon/GLP-1 Mimetic, Improves MASH in 83% of Phase 2 Trial Participants.

Published in:

Patient Care (Online), 2024, p. 1

By:

Halsey, Grace

Publication type:

Article

Perspective: Graduation time.

Published in:

Nature, 2013, v. 502, n. 7470, p. S7, doi. 10.1038/502S7a

By:

Russell, David G.;
Nathan, Carl F.

Publication type:

Article

Kinetics and Mechanism of Explosive Decomposition of Heavy Metal Azides.

Published in:

Combustion, Explosion, & Shock Waves, 2006, v. 42, n. 1, p. 94, doi. 10.1007/s10573-006-0012-z

By:

Korepanov, V. I.;
Lisitsyn, V. M.;
Oleshko, V. I.;
Tsipilev, V. P.

Publication type:

Article

Linking diacylglycerol kinase to T cell anergy.

Published in:

Nature Immunology, 2006, v. 7, n. 11, p. 1132, doi. 10.1038/ni1106-1132

By:

Mueller, Daniel L.

Publication type:

Article

Determining the Mechanisms of Toxic Action of Phenols to Tetrahymena pyriformis.

Published in:

Environmental Toxicology, 2002, v. 17, n. 2, p. 119, doi. 10.1002/tox.10040

By:

Ren, S.

Publication type:

Article

Hexavalent Chromium in Drinking Water.

Published in:

Journal: American Water Works Association, 2018, v. 110, n. 5, p. E22, doi. 10.1002/awwa.1044

By:

Moffat, Ivy;
Martinova, Nadia;
Seidel, Chad;
Thompson, Chad M.

Publication type:

Article

Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach.

Published in:

NPJ Systems Biology & Applications, 2017, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41540-017-0013-4

By:

Iborra-Egea, Oriol;
Gálvez-Montón, Carolina;
Roura, Santiago;
Perea-Gil, Isaac;
Prat-Vidal, Cristina;
Soler-Botija, Carolina;
Bayes-Genis, Antoni

Publication type:

Article

Just say N<sub>2</sub>O – nitrous oxide misuse: essential information for psychiatrists.

Published in:

BJPsych Advances, 2020, v. 26, n. 2, p. 72, doi. 10.1192/bja.2019.57

By:

Sheldon, Rollo J. G.;
Reid, Michael;
Schon, Frederick;
Poole, Norman A.

Publication type:

Article

Clinical neuromodulation in psychiatry: the state of the art or an art in a state?

Published in:

BJPsych Advances, 2015, v. 21, n. 6, p. 396, doi. 10.1192/apt.bp.115.014563

By:

Tracy, Derek K.;
David, Anthony S.

Publication type:

Article

Toxicity of cyanobacteria. Organotropy of cyanotoxins and toxicodynamics of cyanotoxins by species.

Published in:

Pharmacia (0428-0296), 2019, v. 66, n. 3, p. 91, doi. 10.3897/pharmacia.66.e37035

By:

Ilieva, Victoria;
Kondeva-Burdina, Magdalena;
Georgieva, Tzveta;
Pavlova, Vera

Publication type:

Article

Network pharmacology-based assessment to elucidate the molecular mechanism of anti-diabetic action of Tinospora cordifolia.

Published in:

Clinical Phytoscience, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1186/s40816-019-0131-1

By:

Khanal, Pukar;
Patil, B. M.;
Mandar, Bijendra K.;
Dey, Yadu Nandan;
Duyu, Taaza

Publication type:

Article

Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. Rich on haematological and biochemical parameters in healthy Wistar rats.

Published in:

Clinical Phytoscience, 2019, v. 5, n. 1, p. 1, doi. 10.1186/s40816-019-0104-4

By:

Oso, Babatunde Joseph;
Oyewo, Emmanuel Bukoye;
Oladiji, Adenike Temidayo

Publication type:

Article

Circadian Organization in Male Mice Lacking the Gene for Endothelial Nitric Oxide Synthase (eNOS-/-).

Published in:

Journal of Biological Rhythms, 2001, v. 16, n. 2, p. 142, doi. 10.1177/074873001129001845

By:

Kriegsfeld, Lance J.;
Drazen, Deborah L.;
Nelson, Randy J.

Publication type:

Article

A Reexamination of the Role of GABA in the Mammalian Suprachiasmatic Nucleus.

Published in:

Journal of Biological Rhythms, 1999, v. 14, n. 2, p. 126, doi. 10.1177/074873099129000515

By:

Gribkoff, Valentin K.;
Pieschl, Rick L.;
Wisialowski, Todd A.;
Park, Won K.;
Strecker, George J.;
de Jeu, Marcel T. G.;
Pennartz, Cyriel M. A.;
Dudek, F. Edward

Publication type:

Article

Activation and maturation of antigen-presenting dendritic cells during vaccine therapy in patients with chronic hepatitis due to hepatitis B virus.

Published in:

Hepatology Research, 2002, v. 23, n. 1, p. 38, doi. 10.1016/S1386-6346(01)00165-6

By:

Horiike, Norio;
Md. Fazle Akbar, Sk.;
Ninomiya, Tuneyuki;
Abe, Masanori;
Michitaka, Kojiro;
Onji, Morikazu

Publication type:

Article

Protein kinase and NO-stimulated ADP-ribosyltransferase activities associated with glyceraldehyde-3-phosphate dehydrogenase isolated from human liver

Published in:

Hepatology Research, 2002, v. 22, n. 1, p. 65, doi. 10.1016/S1386-6346(01)00111-5

By:

Duclos-Vallée, Jean-Charles;
Capel, Francis;
Mabit, Hélène;
Petit, Marie-Anne

Publication type:

Article

Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 6, p. 1355, doi. 10.1038/npp.2013.331

By:

Baumann, Michael H;
Bulling, Simon;
Benaderet, Tova S;
Saha, Kusumika;
Ayestas, Mario A;
Partilla, John S;
Ali, Syed F;
Stockner, Thomas;
Rothman, Richard B;
Sandtner, Walter;
Sitte, Harald H

Publication type:

Article

Ligand functional selectivity advances our understanding of drug mechanisms and drug discovery.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 1, p. 345, doi. 10.1038/npp.2009.117

By:

Mailman, Richard B.;
Murthy, Vishakantha

Publication type:

Article

Modafinil: an anti-relapse medication.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 1, p. 343, doi. 10.1038/npp.2009.123

By:

Tahsili-Fahadan, Pouya;
Malcolm, Robert;
Aston-Jones, Gary

Publication type:

Article

Therapeutic and pharmacological aspects of photodynamic product chlorophyllin.

Published in:

European Journal of Biological Research, 2019, v. 9, n. 2, p. 64, doi. 10.5281/zenodo.2638869

By:

Chaturvedi, Divya;
Singh, Kavita;
Singh, Vinay Kumar

Publication type:

Article

Dynamics of biochemical changes in anxious-depressed patients under treatment with antidepressants with different mechanisms of action on serotonin reuptake.

Published in:

European Psychiatry, 2016, v. 33, p. S123, doi. 10.1016/j.eurpsy.2016.01.139

By:

Uzbekov, M.;
Maximova, N.

Publication type:

Article

Structure of Self-stigmatization in Cases of Schizophrenia.

Published in:

European Psychiatry, 2015, v. 30, p. 1688, doi. 10.1016/S0924-9338(15)31294-3

By:

Kim, A.S.;
Cherapkin, E.S.

Publication type:

Article

P-1311 - Neurocognitive deficit correction in patients with schizophrenia

Published in:

2012

By:

Sofronov, A.;
Spikina, A.;
Savelyev, A.

Publication type:

Abstract