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- Title
Effect of Curcumin and Black tea Extract on Breast, Liver and Colon Cancer Cells, Studying the Effect of raw Turmeric Powder Hangover on Adsorption of Heavy Metal.
- Authors
Hussein, Azhar Maher; Badawy, Nagwa A.; Elbayaa, A. A.; Zaahkouk, S. A. M.; Emam, Abeer A.; Miski, Samar F.; Belal, Amany; Mehany, Ahmed B. M.
- Abstract
Objective/Background: Curcumin is a phenolic molecule found in turmeric, it has a wide range of pharmacological actions and is being studied in clinical investigations for the treatment of many illnesses. The durability of turmeric as a natural coloring agent in various media is not well understood. Numerous variables including additives can change the stability of turmeric. Therefore, it is interesting to investigate the stability of turmeric in different additive combinations. Methods: To examine the following three main areas: (1) the impact of different additives (green and black tea) on the kinetic analysis and chemical stability of commercial turmeric as a natural mixture of curcuminoids. (2) Study the adsorption of Cr (III) by raw turmeric powder hangover and (3) the anticancer activity of both turmeric raw material and black tea. Results: Investigations of the extract on human cancer cells as breast, colon and liver using Sulphorhodamine B (SRB) assay method shwoed a good anticancer activity of black tea and the extracted turmeric raw material. Conclusion: Raw turmeric powder hangover has effect on adsorption of heavy metal, also curcumin and black tea extract have anticancer activity against the tested cancer cells, IC50 value ranged from 0.25 to 2.5 μg/ml.
- Subjects
LIVER cancer; COLON cancer; TEA extracts; RAW materials; ANALYTICAL chemistry; TURMERIC; CURCUMIN
- Publication
Natural Product Communications, 2024, Vol 19, Issue 12, p1
- ISSN
1934-578X
- Publication type
Academic Journal
- DOI
10.1177/1934578X241302575