Works matching DE "HEART fibrosis"

Results: 1818

Emerging Epigenetic Therapies for the Treatment of Cardiac Fibrosis.

Published in:

Biomedicines, 2025, v. 13, n. 5, p. 1170, doi. 10.3390/biomedicines13051170

By:

Garitano, Nerea;
Aguado-Alvaro, Laura Pilar;
Pelacho, Beatriz

Publication type:

Article

Molecular Imaging of Fibroblast Activation Protein in Response to Cardiac Injury Using [ 68 Ga]Ga-DATA 5m.SA.FAPi.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 658, doi. 10.3390/ph18050658

By:

Weissenböck, Victoria;
Weber, Lukas;
Schlederer, Michaela;
Silva Sousa, Laura;
Stampfer, Anna;
Baydar, Simge;
Nakuz, Thomas;
Calabretta, Raffaella;
Antunes Goncalves, Ana Isabel;
Li, Xiang;
Rösch, Frank;
Podesser, Bruno K.;
Kenner, Lukas;
Hacker, Marcus;
Kiss, Attila;
Philippe, Cecile

Publication type:

Article

Tissue-Resident Macrophages in Cardiovascular Diseases: Heterogeneity and Therapeutic Potential.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4524, doi. 10.3390/ijms26104524

By:

An, Tianhui;
Guo, Mengyuan;
Wang, Zhaohui;
Liu, Kun

Publication type:

Article

Sodium–Glucose Cotransporter 2 Inhibitors in Aortic Stenosis: Toward a Comprehensive Cardiometabolic Approach.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4494, doi. 10.3390/ijms26104494

By:

Karakasis, Paschalis;
Theofilis, Panagiotis;
Patoulias, Dimitrios;
Vlachakis, Panayotis K.;
Pamporis, Konstantinos;
Sagris, Marios;
Ktenopoulos, Nikolaos;
Kassimis, George;
Antoniadis, Antonios P.;
Fragakis, Nikolaos

Publication type:

Article

Pravastatin attenuates isoprenaline induced cardiac fibrosis in a mouse model.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 8, p. 567, doi. 10.1080/10520295.2023.2260303

By:

Rana, Abhinav;
Singh, Thakur Uttam;
Sharma, Meemansha;
Gari, Manju;
Kumar, Tarun;
Parida, Subhashree;
Lingaraju, Madhu Cholenahalli;
Kumar Mariappan, Asok;
Kumar, Akhilesh;
Kumar, Dinesh

Publication type:

Article

Iron toxicity mediated by oxidative stress enhances tissue damage in an animal model of diabetes.

Published in:

BioMetals, 2014, v. 27, n. 2, p. 349, doi. 10.1007/s10534-014-9717-8

By:

Sampaio, Ana;
Silva, Maisa;
Dornas, Waleska;
Costa, Daniela;
Silva, Marcelo;
Santos, Rinaldo;
Lima, Wanderson;
Pedrosa, Maria

Publication type:

Article

Impaired Myocardial Work in Children with Hypertrophic Cardiomyopathy and Left Ventricular Fibrosis on Cardiac Magnetic Resonance Imaging.

Published in:

Pediatric Cardiology, 2025, v. 46, n. 5, p. 1254, doi. 10.1007/s00246-024-03543-4

By:

Jacquemyn, Xander;
Long, Rita;
Rao, Sruti;
Danford, David;
Barnes, Benjamin T.;
Kutty, Shelby

Publication type:

Article

Cardiac and Liver Fibrosis Assessed by Multiparametric MRI in Patients with Fontan Circulation.

Published in:

Pediatric Cardiology, 2025, v. 46, n. 4, p. 966, doi. 10.1007/s00246-024-03522-9

By:

Innocenzi, Adriana;
Rangel, Isabela;
Póvoa-Corrêa, Mariana;
Parente, Daniella Braz;
Perez, Renata;
Rodrigues, Rosana Souza;
Fukuyama, Lúcia Tomoko;
Barroso, Julia Machado;
Oliveira Neto, Jaime Araújo;
Silvestre de Sousa, Andréa;
Luiz, Ronir Raggio;
Barbosa, Rosa Célia Pimentel;
Camargo, Gabriel Cordeiro;
Moll-Bernardes, Renata

Publication type:

Article

High ECG Risk-Scores Predict Late Gadolinium Enhancement on Magnetic Resonance Imaging in HCM in the Young.

Published in:

Pediatric Cardiology, 2021, v. 42, n. 3, p. 492, doi. 10.1007/s00246-020-02506-9

By:

Österberg, Anna Wålinder;
Östman-Smith, Ingegerd;
Jablonowski, Robert;
Carlsson, Marcus;
Green, Henrik;
Gunnarsson, Cecilia;
Liuba, Petru;
Fernlund, Eva

Publication type:

Article

Troponin I Levels Correlate with Cardiac MR LGE and Native T1 Values in Duchenne Muscular Dystrophy Cardiomyopathy and Identify Early Disease Progression.

Published in:

Pediatric Cardiology, 2020, v. 41, n. 6, p. 1173, doi. 10.1007/s00246-020-02372-5

By:

Voleti, Sonia;
Olivieri, Laura;
Hamann, Karin;
Gordish-Dressman, Heather;
Spurney, Christopher

Publication type:

Article

β3-Adrenergic receptor overexpression in cardiomyocytes preconditions mitochondria to withstand ischemia–reperfusion injury.

Published in:

Basic Research in Cardiology, 2024, v. 119, n. 5, p. 773, doi. 10.1007/s00395-024-01072-y

By:

Fernández-Tocino, Miguel;
Pun-Garcia, Andrés;
Gómez, Mónica;
Clemente-Moragón, Agustín;
Oliver, Eduardo;
Villena-Gutierrez, Rocío;
Trigo-Anca, Sofía;
Díaz-Guerra, Anabel;
Sanz-Rosa, David;
Prados, Belén;
del Campo, Lara;
Andrés, Vicente;
Fuster, Valentín;
de la Pompa, José Luis;
Cádiz, Laura;
Ibañez, Borja

Publication type:

Article

CARD9 promotes autophagy in cardiomyocytes in myocardial ischemia/reperfusion injury via interacting with Rubicon directly.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 3, p. 1, doi. 10.1007/s00395-020-0790-6

By:

Li, Yuanbin;
Liang, Pengfei;
Jiang, Bimei;
Tang, Yuting;
Liu, Xuanyou;
Liu, Meidong;
Sun, Hui;
Chen, Cheng;
Hao, Hong;
Liu, Zhenguo;
Xiao, Xianzhong

Publication type:

Article

TRPV4 deletion protects heart from myocardial infarction-induced adverse remodeling via modulation of cardiac fibroblast differentiation.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 2, p. 1, doi. 10.1007/s00395-020-0775-5

By:

Adapala, Ravi K.;
Kanugula, Anantha K.;
Paruchuri, Sailaja;
Chilian, William M.;
Thodeti, Charles K.

Publication type:

Article

Heart non-specific effector CD4+ T cells protect from postinflammatory fibrosis and cardiac dysfunction in experimental autoimmune myocarditis.

Published in:

Basic Research in Cardiology, 2020, v. 115, n. 1, p. 1, doi. 10.1007/s00395-019-0766-6

By:

Zarak-Crnkovic, Martina;
Kania, Gabriela;
Jaźwa-Kusior, Agnieszka;
Czepiel, Marcin;
Wijnen, Winandus J.;
Czyż, Jarosław;
Müller-Edenborn, Björn;
Vdovenko, Daria;
Lindner, Diana;
Gil-Cruz, Cristina;
Bachmann, Marta;
Westermann, Dirk;
Ludewig, Burkhard;
Distler, Oliver;
Lüscher, Thomas F.;
Klingel, Karin;
Eriksson, Urs;
Błyszczuk, Przemysław

Publication type:

Article

The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3.

Published in:

Basic Research in Cardiology, 2019, v. 114, n. 2, p. 1, doi. 10.1007/s00395-019-0721-6

By:

Zhao, Jing;
Gao, Jin-Lai;
Zhu, Jun-Xue;
Zhu, Hai-Bin;
Peng, Xuan;
Jiang, Man;
Fu, Yao;
Xu, Juan;
Mao, Xi-Hai;
Hu, Nan;
Ma, Ming-Hui;
Dong, De-Li

Publication type:

Article

Blocking the IL-1β signalling pathway prevents chronic viral myocarditis and cardiac remodeling.

Published in:

Basic Research in Cardiology, 2019, v. 114, n. 2, p. 1, doi. 10.1007/s00395-019-0719-0

By:

Kraft, Lisa;
Erdenesukh, Tugs;
Sauter, Martina;
Tschöpe, Carsten;
Klingel, Karin

Publication type:

Article

Inflammation and fibrosis in murine models of heart failure.

Published in:

Basic Research in Cardiology, 2019, v. 114, n. 3, p. N.PAG, doi. 10.1007/s00395-019-0722-5

By:

Bacmeister, Lucas;
Schwarzl, Michael;
Warnke, Svenja;
Stoffers, Bastian;
Blankenberg, Stefan;
Westermann, Dirk;
Lindner, Diana

Publication type:

Article

Amphiregulin enhances cardiac fibrosis and aggravates cardiac dysfunction in mice with experimental myocardial infarction partly through activating EGFR-dependent pathway.

Published in:

Basic Research in Cardiology, 2018, v. 113, n. 2, p. 0, doi. 10.1007/s00395-018-0669-y

By:

Liu, Liang;
Jin, Xian;
Hu, Cui-Fen;
Zhang, Ya-Ping;
Zhou, Zhong’e;
Li, Rong;
Shen, Cheng-Xing

Publication type:

Article

Periostin in cardiovascular disease and development: a tale of two distinct roles.

Published in:

Basic Research in Cardiology, 2018, v. 113, n. 1, p. 1, doi. 10.1007/s00395-017-0659-5

By:

Landry, Natalie M.;
Cohen, Smadar;
Dixon, Ian M. C.

Publication type:

Article

The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation.

Published in:

Basic Research in Cardiology, 2017, v. 112, n. 4, p. 1, doi. 10.1007/s00395-017-0634-1

By:

Wang, Qian;
Yu, Ying;
Zhang, Pengpai;
Chen, Yihe;
Li, Changyi;
Chen, Jie;
Wang, Yuepeng;
Li, Yigang

Publication type:

Article

Dissecting the role of myeloid and mesenchymal fibroblasts in age-dependent cardiac fibrosis.

Published in:

Basic Research in Cardiology, 2017, v. 112, n. 4, p. 1, doi. 10.1007/s00395-017-0623-4

By:

Trial, JoAnn;
Heredia, Celia;
Taffet, George;
Entman, Mark;
Cieslik, Katarzyna

Publication type:

Article

Time to quit that marathon running? Not quite yet!

Published in:

2014

By:

Noakes, Timothy

Publication type:

Editorial

Increased afterload induces pathological cardiac hypertrophy: a new in vitro model.

Published in:

Basic Research in Cardiology, 2012, v. 107, n. 6, p. 1, doi. 10.1007/s00395-012-0307-z

By:

Hirt, Marc;
Sörensen, Nils;
Bartholdt, Lena;
Boeddinghaus, Jasper;
Schaaf, Sebastian;
Eder, Alexandra;
Vollert, Ingra;
Stöhr, Andrea;
Schulze, Thomas;
Witten, Anika;
Stoll, Monika;
Hansen, Arne;
Eschenhagen, Thomas

Publication type:

Article

Role of miR-21 in the pathogenesis of atrial fibrosis.

Published in:

Basic Research in Cardiology, 2012, v. 107, n. 5, p. 1, doi. 10.1007/s00395-012-0278-0

By:

Adam, Oliver;
Löhfelm, Björn;
Thum, Thomas;
Gupta, Shashi;
Puhl, Sarah-Lena;
Schäfers, Hans-Joachim;
Böhm, Michael;
Laufs, Ulrich

Publication type:

Article

Distinct mechanisms for diastolic dysfunction in diabetes mellitus and chronic pressure-overload.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 5, p. 801, doi. 10.1007/s00395-011-0184-x

By:

Falcão-Pires, Inês;
Palladini, Giuseppina;
Gonçalves, Nádia;
Velden, Jolanda;
Moreira-Gonçalves, Daniel;
Miranda-Silva, Daniela;
Salinaro, Francesco;
Paulus, Walter;
Niessen, Hans;
Perlini, Stefano;
Leite-Moreira, Adelino

Publication type:

Article

Desmoglein 2 mutant mice develop cardiac fibrosis and dilation.

Published in:

Basic Research in Cardiology, 2011, v. 106, n. 4, p. 617, doi. 10.1007/s00395-011-0175-y

By:

Krusche, Claudia;
Holthöfer, Bastian;
Hofe, Valérie;
Sandt, Annette;
Eshkind, Leonid;
Bockamp, Ernesto;
Merx, Marc;
Kant, Sebastian;
Windoffer, Reinhard;
Leube, Rudolf

Publication type:

Article

TGF-β1 improves cardiac performance via up-regulation of laminin receptor 37/67 in adult ventricular cardiomyocytes.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 5, p. 621, doi. 10.1007/s00395-010-0108-1

By:

Wenzel, Sibylle;
Henning, Kirsten;
Habbig, Andreas;
Forst, Svenja;
Schreckenberg, Rolf;
Heger, Jacqueline;
Maxeiner, Hagen;
Schlüter, Klaus-Dieter

Publication type:

Article

Reduced MMP-2 activity contributes to cardiac fibrosis in experimental diabetic cardiomyopathy.

Published in:

Basic Research in Cardiology, 2008, v. 103, n. 4, p. 319, doi. 10.1007/s00395-008-0715-2

By:

Linthout, Sophie Van;
Seeland, Ute;
Riad, Alexander;
Eckhardt, Oleg;
Hohl, Mathias;
Dhayat, Nasser;
Richter, Utz;
Fischer, Jens W.;
Böhm, Michael;
Pauschinger, Matthias;
Schultheiss, Heinz-Peter;
Tschöpe, Carsten

Publication type:

Article

Transforming growth factor-β receptor antagonism attenuates myocardial fibrosis in mice with cardiac-restricted overexpression of tumor necrosis factor.

Published in:

Basic Research in Cardiology, 2008, v. 103, n. 1, p. 60, doi. 10.1007/s00395-007-0689-5

By:

Sakata, Yasushi;
Chancey, Amanda;
Divakaran, Vijay;
Sekiguchi, Kenichi;
Sivasubramanian, Natarajan;
Mann, Douglas

Publication type:

Article

ACE–inhibitor treatment attenuates atrial structural remodeling in patients with lone chronic atrial fibrillation.

Published in:

Basic Research in Cardiology, 2006, v. 101, n. 3, p. 261, doi. 10.1007/s00395-005-0571-2

By:

Boldt, Andreas;
Scholl, Anja;
Garbade, Jens;
Resetar, Michaela E.;
Mohr, Friedrich Wilhelm;
Gummert, Jan Fritz;
Dhein, Stefan

Publication type:

Article

Atrial fibrosis in heart surgery patients.

Published in:

Basic Research in Cardiology, 2005, v. 100, n. 3, p. 288, doi. 10.1007/s00395-005-0515-x

By:

Grammer, Joachim Burkhard;
Böhm, Johannes;
Dufour, Annika;
Benz, Matthias;
Lange, Rüdiger;
Bauernschmitt, Robert

Publication type:

Article

Alarin alleviated cardiac fibrosis via attenuating oxidative stress in heart failure rats.

Published in:

Amino Acids, 2021, v. 53, n. 7, p. 1079, doi. 10.1007/s00726-021-03005-8

By:

Li, Jinshuang;
Ding, Hao;
Li, Yong;
Zhou, Hao;
Wang, Wanhong;
Mei, Yong;
Zhang, Ronglin

Publication type:

Article

The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α<sub>1</sub>-adrenergic receptors.

Published in:

Biochemical Journal, 2021, v. 478, n. 11, p. 2059, doi. 10.1042/BCJ20210144

By:

Meijles, Daniel N.;
Fuller, Stephen J.;
Cull, Joshua J.;
Alharbi, Hajed O.;
Cooper, Susanna T. E.;
Sugden, Peter H.;
Clerk, Angela

Publication type:

Article

Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation.

Published in:

Biochemical Journal, 2020, v. 477, n. 17, p. 3401, doi. 10.1042/BCJ20200360

By:

Ghiroldi, Andrea;
Piccoli, Marco;
Creo, Pasquale;
Cirillo, Federica;
Rota, Paola;
D'Imperio, Sara;
Ciconte, Giuseppe;
Monasky, Michelle M.;
Micaglio, Emanuele;
Garatti, Andrea;
Aureli, Massimo;
Carsana, Emma Veronica;
Menicanti, Lorenzo;
Pappone, Carlo;
Anastasia, Luigi

Publication type:

Article

Ferroptosis: A New Strategy for the Treatment of Fibrotic Diseases.

Published in:

Advanced Biology, 2025, v. 9, n. 3, p. 1, doi. 10.1002/adbi.202400383

By:

Pei, Zhuo;
Fan, Jing;
Tang, Maolin;
Li, Yuhong

Publication type:

Article

Development of a Mouse Cardiac Sarcoidosis Model Using Carbon Nanotubes.

Published in:

Advanced Biology, 2024, v. 8, n. 9, p. 1, doi. 10.1002/adbi.202400238

By:

Van Remortel, Sophie;
Risha, Yousef;
Parent, Sandrine;
Nair, Vidhya;
Birnie, David H.;
Davis, Darryl R.

Publication type:

Article

Elevated Levels of Cerium in Tubers from Regions Endemic for Endomyocardial Fibrosis (EMF).

Published in:

Bulletin of Environmental Contamination & Toxicology, 1998, v. 60, n. 1, p. 168, doi. 10.1007/s001289900606

By:

Eapen, J. T.

Publication type:

Article

Magnesium Deficiency and Cerium Promote Fibrogenesis in Rat Heart.

Published in:

Bulletin of Environmental Contamination & Toxicology, 1996, v. 57, n. 4, p. 517, doi. 10.1007/s001289900220

By:

Kumar, B. P.;
Shivakumar, K.;
Kartha, C. C.;
Rathinam, K.

Publication type:

Article

Advancing 3D Engineered In Vitro Models for Heart Failure Research: Key Features and Considerations.

Published in:

Bioengineering (Basel), 2024, v. 11, n. 12, p. 1220, doi. 10.3390/bioengineering11121220

By:

van Doorn, Elisa C. H.;
Amesz, Jorik H.;
Manintveld, Olivier C.;
de Groot, Natasja M. S.;
Essers, Jeroen;
Shin, Su Ryon;
Taverne, Yannick J. H. J.

Publication type:

Article

Changes in Serum Levels of Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinases-1 in Patients with Essential Hypertension.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 3, p. 119, doi. 10.3390/bioengineering9030119

By:

Kostov, Krasimir;
Blazhev, Alexander

Publication type:

Article

Simvastatin Attenuates Cardiac Fibrosis via Regulation of Cardiomyocyte-Derived Exosome Secretion.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 6, p. 794, doi. 10.3390/jcm8060794

By:

Kuo, Hsuan-Fu;
Hsieh, Chong-Chao;
Wang, Shu-Chi;
Chang, Chia-Yuan;
Hung, Chih-Hsin;
Kuo, Po-Lin;
Liu, Yu-Ru;
Li, Chia-Yang;
Liu, Po-Len

Publication type:

Article

Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with Myocardial Infarction and Isoproterenol-Treated Rats.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 659, doi. 10.3390/jcm8050659

By:

Lin, Chao-Feng;
Su, Chih-Jou;
Liu, Jia-Hong;
Chen, Shui-Tien;
Huang, Han-Li;
Pan, Shiow-Lin

Publication type:

Article

Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients.

Published in:

Journal of Clinical Medicine, 2018, v. 7, n. 11, p. 427, doi. 10.3390/jcm7110427

By:

Wu, Cho-Kai;
Su, Mao-Yuan M.;
Wu, Yi-Fan;
Hwang, Juey-Jen;
Lin, Lian-Yu

Publication type:

Article

The Soft-and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.

Published in:

Journal of Clinical Medicine, 2017, v. 6, n. 5, p. 53, doi. 10.3390/jcm6050053

By:

Herum, Kate M.;
Lunde, Ida G.;
McCulloch, Andrew D.;
Christensen, Geir

Publication type:

Article

Role of Quercetin in Diabetic Cardiomyopathy.

Published in:

Plants (2223-7747), 2025, v. 14, n. 1, p. 25, doi. 10.3390/plants14010025

By:

Mustafa, Nor Hidayah;
Siti, Hawa Nordin;
Kamisah, Yusof

Publication type:

Article

Fibroblast-derived interleukin-6 exacerbates adverse cardiac remodeling after myocardial infarction.

Published in:

Korean Journal of Physiology & Pharmacology, 2024, v. 28, n. 3, p. 285, doi. 10.4196/kjpp.2024.28.3.285

By:

Hongkun Li;
Yunfei Bian

Publication type:

Article

Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2023, v. 27, n. 1, p. 1, doi. 10.4196/kjpp.2023.27.1.1

By:

Xiong Song;
Liangui Nie;
Junrong Long;
Junxiong Zhao;
Xing Liu;
Liuyang Wang;
Da Liu;
Sen Wang;
Shengquan Liu;
Jun Yang

Publication type:

Article

Neogambogic acid relieves myocardial injury induced by sepsis via p38 MAPK/NF-κB pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 6, p. 511, doi. 10.4196/kjpp.2022.26.6.511

By:

Wei Fu;
Xiaowei Fang;
Lidong Wu;
Weijuan Hu;
Tao Yang

Publication type:

Article

Corrigendum.

Published in:: Korean Journal of Physiology & Pharmacology, 2021, v. 25, n. 3, p. 259, doi. 10.4196/kjpp.2021.25.3.259
Publication type:: Article

Mangiferin ameliorates cardiac fibrosis in D-galactose-induced aging rats by inhibiting TGF-β/p38/MK2 signaling pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2021, v. 25, n. 2, p. 131, doi. 10.4196/kjpp.2021.25.2.131

By:

Jing Cheng;
Chaoyang Ren;
Renli Cheng;
Yunning Li;
Ping Liu;
Wei Wang;
Li Liu

Publication type:

Article