Works matching DE "PROTEASOME inhibitors"

Results: 1114

Sequence composition of disordered regions fine-tunes protein half-life.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 214, doi. 10.1038/nsmb.2958

By:

Fishbain, Susan;
Inobe, Tomonao;
Israeli, Eitan;
Chavali, Sreenivas;
Yu, Houqing;
Kago, Grace;
Babu, M Madan;
Matouschek, Andreas

Publication type:

Article

The proteasome gets a grip on protein complexity.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 181, doi. 10.1038/nsmb.2977

By:

Humbard, Matthew A;
Maurizi, Michael R

Publication type:

Article

Conformational switching of the 26S proteasome enables substrate degradation.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 781, doi. 10.1038/nsmb.2616

By:

Matyskiela, Mary E;
Lander, Gabriel C;
Martin, Andreas

Publication type:

Article

Development of Potent and Highly Selective Epoxyketone‐Based Plasmodium Proteasome Inhibitors.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 20, p. 1, doi. 10.1002/chem.202203958

By:

Almaliti, Jehad;
Fajtová, Pavla;
Calla, Jaeson;
LaMonte, Gregory M.;
Feng, Mudong;
Rocamora, Frances;
Ottilie, Sabine;
Glukhov, Evgenia;
Boura, Evzen;
Suhandynata, Raymond T.;
Momper, Jeremiah D.;
Gilson, Michael K.;
Winzeler, Elizabeth A.;
Gerwick, William H.;
O'Donoghue, Anthony J.

Publication type:

Article

(Immuno)proteasomes as therapeutic target in acute leukemia.

Published in:

Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 599, doi. 10.1007/s10555-017-9699-4

By:

Cloos, Jacqueline;
Roeten, Margot;
Franke, Niels;
Meerloo, Johan;
Zweegman, Sonja;
Kaspers, Gertjan;
Jansen, Gerrit

Publication type:

Article

Emerging small molecule approaches to enhance the antimyeloma benefit of proteasome inhibitors.

Published in:

Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 585, doi. 10.1007/s10555-017-9698-5

By:

Driscoll, James;
Brailey, Magen

Publication type:

Article

The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities.

Published in:

Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 617, doi. 10.1007/s10555-017-9700-2

By:

Zaky, Wafik;
Manton, Christa;
Miller, Claudia;
Khatua, Soumen;
Gopalakrishnan, Vidya;
Chandra, Joya

Publication type:

Article

Targeting the ubiquitin-proteasome system for cancer treatment: discovering novel inhibitors from nature and drug repurposing.

Published in:

Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 717, doi. 10.1007/s10555-017-9705-x

By:

Soave, Claire;
Guerin, Tracey;
Liu, Jinbao;
Dou, Q. Ping

Publication type:

Article

The proteasome and proteasome inhibitors in multiple myeloma.

Published in:

Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 561, doi. 10.1007/s10555-017-9707-8

By:

Gandolfi, Sara;
Laubach, Jacob;
Hideshima, Teru;
Chauhan, Dharminder;
Anderson, Kenneth;
Richardson, Paul

Publication type:

Article

Preface.

Published in:

Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 559, doi. 10.1007/s10555-017-9706-9

By:

Dou, Q.

Publication type:

Article

Biography-Q. Ping Dou.

Published in:: Cancer & Metastasis Reviews, 2017, v. 36, n. 4, p. 557, doi. 10.1007/s10555-017-9708-7
Publication type:: Article

The therapeutic challenge of late antibody‐mediated kidney allograft rejection.

Published in:

Transplant International, 2019, v. 32, n. 8, p. 775, doi. 10.1111/tri.13436

By:

Böhmig, Georg A.;
Eskandary, Farsad;
Doberer, Konstantin;
Halloran, Philip F.

Publication type:

Article

Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy.

Published in:

Acta Neuropathologica, 2012, v. 124, n. 1, p. 51, doi. 10.1007/s00401-012-0977-5

By:

Stefanova, Nadia;
Kaufmann, Walter;
Humpel, Christian;
Poewe, Werner;
Wenning, Gregor

Publication type:

Article

Cancer: Targeting multiple myeloma.

Published in:: Nature, 2015, v. 521, n. 7550, p. 8, doi. 10.1038/521008c
Publication type:: Article

Dichlorodiphenyldichloroethylene exposure reduces r-GCS via suppressed Nrf2 in HepG2 cells.

Published in:

Environmental Toxicology, 2016, v. 31, n. 3, p. 350, doi. 10.1002/tox.22049

By:

Jin, Xiaoting;
Song, Li;
Li, Zhuoyu;
Newton, Ian P.;
Zhao, Meirong;
Liu, Weiping

Publication type:

Article

Carfilzomib experience in relapsed/refractory multiple myeloma: a single-center experience.

Published in:

Turkish Journal of Medical Sciences, 2018, v. 48, n. 1, p. 80, doi. 10.3906/sag-1611-97

By:

UYSAL, Ayşe;
AKAD SOYER, Nur;
ÖZKAN, Melda;
ŞAHİN, Fahri;
VURAL, Filiz;
TÖBÜ, Mahmut;
TOMBULOĞLU, Murat;
SAYDAM, Güray

Publication type:

Article

The combined effects of proteasome inhibitor bortezomib with topoisomerase I and II inhibitors on topoisomerase enzymes.

Published in:

Turkish Journal of Medical Sciences, 2016, v. 46, n. 6, p. 1882, doi. 10.3906/sag-1511-184

By:

ÖKSÜZOĞLU, Emine;
TIRINOĞLU, Çiydem;
KERİMOĞLU, Barış

Publication type:

Article

Dysfunction of the Ubiquitin Proteasome and Ubiquitin-Like Systems in Schizophrenia.

Published in:

Neuropsychopharmacology, 2013, v. 38, n. 10, p. 1910, doi. 10.1038/npp.2013.84

By:

Rubio, María D;
Wood, Krista;
Haroutunian, Vahram;
Meador-Woodruff, James H

Publication type:

Article

多发性骨髓瘤患者硼替佐米治疗相关带状疱疹发病机理及预防策略研究进展

Published in:

Progress in Modern Biomedicine, 2019, v. 19, n. 13, p. 2592, doi. 10.13241/j.cnki.pmb.2019.13.044

By:

徐莉;
唐海龙;
郑焱华;
冯娟;
王凯;
高广勋

Publication type:

Article

The role of proteasome inhibitor MG132 in cisplatin resistant ovarian cancer.

Published in:

European Journal of Gynaecological Oncology, 2023, v. 44, n. 4, p. 28, doi. 10.22514/ejgo.2023.055

By:

Bailing ZHANG;
Na GUO

Publication type:

Article

Disulfiram, as a candidate NF-ΚB and proteasome inhibitor, prevents endometriotic implant growing in a rat model of endometriosis.

Published in:

European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 20, p. 4380

By:

CELIK, O.;
ERSAHIN, A.;
ACET, M.;
CELIK, N.;
BAYKUS, Y.;
DENIZ, R.;
OZEROL, E.;
OZEROL, I.

Publication type:

Article

Zastosowanie oksykodonu/naloksonu w terapii leczenia bólu u pacjenta ze szpiczakiem plazmocytowym.

Published in:

Anaesthesiology & Rescue Medicine / Anestezjologia i Ratownictwo, 2016, v. 10, n. 4, p. 382

By:

Kotwica-Mojzych, Katarzyna;
Szudy-Szczyrek, Aneta;
Jawniak, Dariusz;
Mojzych, Mariusz;
Hus, Marek

Publication type:

Article

Nocardia farcinica Brain Abscess in a Multiple Myeloma Patient Treated with Proteasome Inhibitor: A Case Report and Review of the Literature.

Published in:

2021

By:

Xu, Nengwen;
Li, Linjie;
Lei, Wen;
Qian, Wenbin

Publication type:

Case Study

Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 1, p. 76, doi. 10.3390/biom15010076

By:

St. Thomas, Nadia;
Christopher, Benjamin N.;
Reyes, Leticia;
Robinson, Reeder M.;
Golick, Lena;
Zhu, Xiaoyi;
Chapman, Eli;
Dolloff, Nathan G.

Publication type:

Article

The Proteasome Activator PA200/PSME4: An Emerging New Player in Health and Disease.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 8, p. 1150, doi. 10.3390/biom12081150

By:

Yazgili, Ayse Seda;
Ebstein, Frédéric;
Meiners, Silke

Publication type:

Article

Metformin Induces Resistance of Cancer Cells to the Proteasome Inhibitor Bortezomib.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 6, p. 756, doi. 10.3390/biom12060756

By:

Schlesser, Camille;
Meul, Thomas;
Stathopoulos, Georgios;
Meiners, Silke

Publication type:

Article

Editorial: Proteomic and metabolic reprogramming in myeloma cells within the tumor microenvironment.

Published in:

Frontiers in Oncology, 2023, p. 01, doi. 10.3389/fonc.2023.1264740

By:

Milan, Enrico;
Gullà, Annamaria

Publication type:

Article

Case report: Preclinical efficacy of NEDD8 and proteasome inhibitors in patient-derived models of signet ring high-grade mucinous colorectal cancer from a Lynch syndrome patient.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1130852

By:

Torchiaro, Erica;
Petti, Consalvo;
Arena, Sabrina;
Sassi, Francesco;
Migliardi, Giorgia;
Mellano, Alfredo;
Porporato, Roberta;
Basiricò, Marco;
Gammaitoni, Loretta;
Berrino, Enrico;
Montone, Monica;
Corti, Giorgio;
Crisafulli, Giovanni;
Marchiò, Caterina;
Bardelli, Alberto;
Medico, Enzo

Publication type:

Article

Sec61 blockade therapy overrides resistance to proteasome inhibitors and immunomodulatory drugs in multiple myeloma.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1110916

By:

Domenger, Antoine;
Ricci, Daniela;
Mayau, Véronique;
Majlessi, Laleh;
Marcireau, Christophe;
Dadaglio, Gilles;
Demangel, Caroline

Publication type:

Article

Proteasome-dependent senescent tumor cells mediate immunosuppression through CCL20 secretion and M2 polarization in pancreatic ductal adenocarcinoma.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1216376

By:

Mengwei Wu;
Jiashu Han;
Hao Wu;
Ziwen Liu

Publication type:

Article

PRKX down-regulates TAK1/IRF7 signaling in the antiviral innate immunity of black carp Mylopharyngodon piceus.

Published in:

Frontiers in Immunology, 2023, v. 13, p. 1, doi. 10.3389/fimmu.2022.999219

By:

Xiao Yang;
Yue Ai;
Liang Chen;
Chanyuan Wang;
Ji Liu;
Jie Zhang;
Jun Li;
Hui Wu;
Jun Xiao;
Mingxian Chang;
Hao Feng

Publication type:

Article

Successful treatment of refractory systemic lupus erythematosus using proteasome inhibitor bortezomib followed by belimumab: description of two cases.

Published in:

Lupus, 2017, v. 26, n. 12, p. 1333, doi. 10.1177/0961203317691371

By:

Sjöwall, C.;
Hjorth, M.;
Eriksson, P.

Publication type:

Article

Manganese activates caspase-9-dependent apoptosis in human bronchial epithelial cells.

Published in:

Human & Experimental Toxicology, 2013, v. 32, n. 11, p. 1155, doi. 10.1177/0960327112470272

By:

Zhang, L;
Sang, H;
Liu, Y;
Li, J

Publication type:

Article

Mitogen-activated protein kinase inhibitors differently affect the growth inhibition and death of a proteasome inhibitor, MG132-treated human pulmonary fibroblast cells.

Published in:

Human & Experimental Toxicology, 2011, v. 30, n. 12, p. 1945, doi. 10.1177/0960327111403173

By:

Park, Woo Hyun

Publication type:

Article

Liposomes Loaded with the Proteasome Inhibitor Z-Leucinyl-Leucinyl-Norleucinal Are Effective in Inducing Apoptosis in Colorectal Cancer Cell Lines.

Published in:

Membranes, 2020, v. 10, n. 5, p. 91, doi. 10.3390/membranes10050091

By:

Cortese, Katia;
Marconi, Silvia;
Aiello, Cinzia;
Gagliani, Maria Cristina;
Pilato, Serena;
Zappacosta, Romina;
Fontana, Antonella;
Castagnola, Patrizio

Publication type:

Article

Understanding biology to tackle the disease: Multiple myeloma from bench to bedside, and back.

Published in:

CA: A Cancer Journal for Clinicians, 2014, v. 64, n. 6, p. 422, doi. 10.3322/caac.21252

By:

Bianchi, Giada;
Anderson, Kenneth C.

Publication type:

Article

Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity.

Published in:

Thyroid, 2024, v. 34, n. 5, p. 659, doi. 10.1089/thy.2023.0514

By:

Iwasaki, Hajime;
Suwanai, Hirotsugu;
Yakou, Fumiyoshi;
Sakai, Hiroyuki;
Ishii, Keitaro;
Hara, Natsuko;
Buckle, Ashley M.;
Kanekura, Kohsuke;
Miyagi, Tamami;
Narumi, Satoshi;
Suzuki, Ryo

Publication type:

Article

Oxidatively modified low‐density lipoproteins are potential mediators of proteasome inhibitor resistance in multiple myeloma.

Published in:

International Journal of Cancer, 2021, v. 148, n. 12, p. 3032, doi. 10.1002/ijc.33497

By:

Polusani, Srikanth R.;
Cortez, Valerie;
Esparza, Javier;
Nguyen, Huynh Nga;
Fan, Hongxin;
Velagaleti, Gopalrao V. N.;
Butler, Matthew J.;
Kinney, Marsha C.;
Oyajobi, Babatunde O.;
Habib, Samy L.;
Asmis, Reto;
Medina, Edward A.

Publication type:

Article

Proteasome inhibitors and Smac mimetics cooperate to induce cell death in diffuse large B‐cell lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis.

Published in:

International Journal of Cancer, 2020, v. 147, n. 5, p. 1485, doi. 10.1002/ijc.32976

By:

Dietz, Anna;
Dalda, Nahide;
Zielke, Svenja;
Dittmann, Jessica;
Wijk, Sjoerd J.L.;
Vogler, Meike;
Fulda, Simone

Publication type:

Article

The NEDD4‐1 E3 ubiquitin ligase: A potential molecular target for bortezomib sensitivity in multiple myeloma.

Published in:

International Journal of Cancer, 2020, v. 146, n. 7, p. 1963, doi. 10.1002/ijc.32615

By:

Huang, Xi;
Gu, Huiyao;
Zhang, Enfan;
Chen, Qingxiao;
Cao, Wen;
Yan, Haimeng;
Chen, Jing;
Yang, Li;
Lv, Ning;
He, Jingsong;
Yi, Qing;
Cai, Zhen

Publication type:

Article

Bortezomib: Safety and Efficacy in the Treatment of Multiple Myeloma.

Published in:

Clinical Medicine Reviews in Oncology, 2010, n. 2, p. 293, doi. 10.4137/CMRO.S1631

By:

Martin, Tom;
Wolf, Jeffrey

Publication type:

Article

Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38404-w

By:

Deshmukh, Fanindra Kumar;
Ben-Nissan, Gili;
Olshina, Maya A.;
Füzesi-Levi, Maria G.;
Polkinghorn, Caley;
Arkind, Galina;
Leushkin, Yegor;
Fainer, Irit;
Fleishman, Sarel J.;
Tawfik, Dan;
Sharon, Michal

Publication type:

Article

Deacetylation induced nuclear condensation of HP1γ promotes multiple myeloma drug resistance.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37013-x

By:

Li, Xin;
Wang, Sheng;
Xie, Ying;
Jiang, Hongmei;
Guo, Jing;
Wang, Yixuan;
Peng, Ziyi;
Hu, Meilin;
Wang, Mengqi;
Wang, Jingya;
Li, Qian;
Wang, Yafei;
Liu, Zhiqiang

Publication type:

Article

The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34654-2

By:

Vdovin, Alexander;
Jelinek, Tomas;
Zihala, David;
Sevcikova, Tereza;
Durech, Michal;
Sahinbegovic, Hana;
Snaurova, Renata;
Radhakrishnan, Dhwani;
Turi, Marcello;
Chyra, Zuzana;
Popkova, Tereza;
Venglar, Ondrej;
Hrdinka, Matous;
Hajek, Roman;
Simicek, Michal

Publication type:

Article

Exploiting endogenous and therapy-induced apoptotic vulnerabilities in immunoglobulin light chain amyloidosis with BH3 mimetics.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33461-z

By:

Fraser, Cameron S.;
Spetz, Johan K. E.;
Qin, Xingping;
Presser, Adam;
Choiniere, Jonathan;
Li, Chendi;
Yu, Stacey;
Blevins, Frances;
Hata, Aaron N.;
Miller, Jeffrey W.;
Bradshaw, Gary A.;
Kalocsay, Marian;
Sanchorawala, Vaishali;
Sarosiek, Shayna;
Sarosiek, Kristopher A.

Publication type:

Article

Bortezomib-Induced Cardiac Tamponade in a 49-Year-Old Man.

Published in:

2018

By:

Burkhart, Taylor;
Keith, Matthew Cody Lee;
Lenneman, Carrie Ann Geisberg;
Fernando, Rajeev Ruben

Publication type:

Case Study

Identification of Long Non-Coding RNAs Deregulated in Multiple Myeloma Cells Resistant to Proteasome Inhibitors.

Published in:

Genes, 2016, v. 7, n. 10, p. 84, doi. 10.3390/genes7100084

By:

Malek, Ehsan;
Byung-Gyu Kim;
Driscoll, James J.

Publication type:

Article

Paradoxical inhibition of cellular protein expression by proteasome inhibitors.

Published in:

Biomolecular Concepts, 2012, v. 3, n. 6, p. 593, doi. 10.1515/bmc-2012-0029

By:

Gartel, Andrei L.

Publication type:

Article

Design, Synthesis and Evaluation of Substituted Aryl-2-Nitrovinyl Derivatives as Small Molecules Proteasome Inhibitors.

Published in:

Iranian Journal of Pharmaceutical Research, 2018, v. 17, n. 3, p. 906

By:

Akhlaghi, Masoud Faghih;
Daeihamed, Marjan;
Ayatollahi, Seyed Abdolmajid;
Kobarfard, Farzad;
Ata, Athar

Publication type:

Article

Targeted treatments for multiple myeloma: specific role of carfilzomib.

Published in:

Pharmacogenomics & Personalized Medicine, 2015, v. 8, p. 23, doi. 10.2147/PGPM.S39085

By:

Sugumar, Dhivya;
Keller, Jesse;
Vij, Ravi

Publication type:

Article