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Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.
- Published in:
- Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02557-5
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- Publication type:
- Article
Declines amongst breeding Eider Somateria mollissima numbers in the Baltic/Wadden Sea flyway.
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- Ornis Fennica, 2012, v. 89, n. 2, p. 81, doi. 10.51812/of.133795
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- Publication type:
- Article
Single-Dose Pharmacokinetics and Pharmacodynamics of RWJ 67657, a Specific p38 Mitogen-Activated Protein Kinase Inhibitor: A First-in-Human Study.
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- Journal of Clinical Pharmacology, 2003, v. 43, n. 4, p. 406
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- Publication type:
- Article
Evidence for activation of histamine H<sub>3</sub> autoreceptors during handling stress in the prefrontal cortex of the rat.
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- Synapse, 2002, v. 43, n. 4, p. 238, doi. 10.1002/syn.10043
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- Publication type:
- Article
No evidence for differential gene expression in major depressive disorder PBMCs, but robust evidence of elevated biological ageing.
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- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01506-4
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- Publication type:
- Article
AWARD SPONSOR.
- Published in:
- Public Sector, 2012, v. 35, n. 4, p. 17
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- Publication type:
- Article
Neuroendocrine and Inflammatory Effects of Childhood Trauma Following Psychosocial and Inflammatory Stress in Women with Remitted Major Depressive Disorder.
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- Brain Sciences (2076-3425), 2019, v. 9, n. 12, p. 375, doi. 10.3390/brainsci9120375
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- Article
Acute nicotine improves social decision-making in non-smoking but not in smoking schizophrenia patients.
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- Frontiers in Neuroscience, 2013, v. 7, p. 1, doi. 10.3389/fnins.2013.00197
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- Publication type:
- Article
In vivo quantification of striatal dopamine D2 receptor occupancy by JNJ-37822681 using [11C]raclopride and positron emission tomography.
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- Journal of Psychopharmacology, 2012, v. 26, n. 8, p. 1128, doi. 10.1177/0269881111435251
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- Publication type:
- Article
Pharmacokinetics and central nervous system effects of the novel dopamine D2 receptor antagonist JNJ-37822681.
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- Journal of Psychopharmacology, 2012, v. 26, n. 8, p. 1119, doi. 10.1177/0269881111415733
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- Publication type:
- Article
p38-MAPK inhibition and endotoxin induced tubular dysfunction in men.
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- Innate Immunity, 2004, v. 10, n. 6, p. 402, doi. 10.1177/09680519040100060401
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- Publication type:
- Article
Markers of Inflammation and Monoamine Metabolism Indicate Accelerated Aging in Bipolar Disorder.
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- Frontiers in Psychiatry, 2018, p. N.PAG, doi. 10.3389/fpsyt.2018.00250
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- Publication type:
- Article
Evaluation of T2-W MR imaging and diffusion-weighted imaging for the early post-treatment local response assessment of patients treated conservatively for cervical cancer: a multicentre study.
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- 2019
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- Publication type:
- journal article
Pharmacokinetic-pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects.
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- British Journal of Clinical Pharmacology, 2011, v. 71, n. 6, p. 886, doi. 10.1111/j.1365-2125.2011.03936.x
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- Publication type:
- Article
DNA double-strand break repair in parental chromatin of mouse zygotes, the first cell cycle as an origin of de novo mutation.
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- Human Molecular Genetics, 2008, v. 17, n. 13, p. 1922, doi. 10.1093/hmg/ddn090
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- Publication type:
- Article
Human Male Meiotic Sex Chromosome Inactivation.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031485
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- Article
Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation.
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- Nature Genetics, 2007, v. 39, n. 2, p. 251, doi. 10.1038/ng1949
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- Publication type:
- Article
Recombinational DNA double-strand breaks in mice precede synapsis.
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- Nature Genetics, 2001, v. 27, n. 3, p. 271, doi. 10.1038/85830
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- Publication type:
- Article
Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications—a position report.
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- Human Reproduction, 2010, v. 25, n. 4, p. 824, doi. 10.1093/humrep/dep465
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- Article
Motile human normozoospermic and oligozoospermic semen samples show a difference in double-strand DNA break incidence.
- Published in:
- 2007
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- Publication type:
- journal article
Correction to: The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder.
- Published in:
- 2019
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- Publication type:
- Correction Notice
The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder.
- Published in:
- Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0553-z
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- Publication type:
- Article
Differential Effects of Inflammatory and Psychosocial Stress on Mood, Hypothalamic-Pituitary-Adrenal Axis, and Inflammation in Remitted Depression.
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- Neuropsychobiology, 2017, v. 74, n. 3, p. 150, doi. 10.1159/000466698
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- Publication type:
- Article
Dosimetric advantages of a clinical daily adaptive plan selection strategy compared with a non-adaptive strategy in cervical cancer radiation therapy.
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- Acta Oncologica, 2017, v. 56, n. 5, p. 667, doi. 10.1080/0284186X.2017.1287949
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- Publication type:
- Article
Dosimetric advantages of proton therapy compared with photon therapy using an adaptive strategy in cervical cancer.
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- Acta Oncologica, 2016, v. 55, n. 7, p. 892, doi. 10.3109/0284186X.2016.1139179
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- Publication type:
- Article
Quantification of delineation errors of the gross tumor volume on magnetic resonance imaging in uterine cervical cancer using pathology data and deformation correction.
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- Acta Oncologica, 2015, v. 54, n. 2, p. 224, doi. 10.3109/0284186X.2014.983655
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- Publication type:
- Article
Nucleotide excision repair in rat male germ cells: low level of repair in intact cells contrasts with high dual incision activity in vitro.
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- Nucleic Acids Research, 2001, v. 29, n. 8, p. 1791, doi. 10.1093/nar/29.8.1791
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- Publication type:
- Article
Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial.
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- 2020
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- Publication type:
- journal article
The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia.
- Published in:
- 2019
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- Publication type:
- journal article
Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants.
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- 2018
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- Publication type:
- journal article
Multiple daytime administration of the selective orexin-2 receptor antagonist JNJ-42847922 induces somnolence in healthy subjects without residual central effects.
- Published in:
- 2018
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- Publication type:
- journal article
A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity.
- Published in:
- 2018
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- Publication type:
- journal article
Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813, a positive allosteric modulator of mGluR2, in two randomised, double-blind phase-I studies.
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- Journal of Psychopharmacology, 2015, v. 29, n. 4, p. 414, doi. 10.1177/0269881115573403
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- Publication type:
- Article
An improved synthesis of the enantiomers of bm-5 and their effects on the central in vivo release of acetylcholine.
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- Chirality, 1992, v. 4, n. 6, p. 367, doi. 10.1002/chir.530040607
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- Publication type:
- Article
Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich.
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- 2018
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- Publication type:
- journal article
Immune and Neuroendocrine Trait and State Markers in Psychotic Illness: Decreased Kynurenines Marking Psychotic Exacerbations.
- Published in:
- Frontiers in Immunology, 2020, v. 10, p. 1, doi. 10.3389/fimmu.2019.02971
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- Publication type:
- Article
PET-Guided Stereotactic Irradiation of Prostate Cancer Lymph Node Metastases.
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- Journal of Nuclear Medicine, 2017, v. 58, n. 1, p. 183, doi. 10.2967/jnumed.116.181149
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- Publication type:
- Article
Sperm-derived histones contribute to zygotic chromatin in humans.
- Published in:
- BMC Developmental Biology, 2008, v. 8, p. 1, doi. 10.1186/1471-213X-8-34
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- Publication type:
- Article