Title: Biofilm Formations in Nasopharyngeal Tissues of Patients with Nasopharyngeal Osteoradionecrosis.
Authors: Tsai, Yih-Jeng; Lin, Yu-Chi; Wu, Wen-Bin; Chiu, Po-Han; Lin, Brian J.; Hao, Sheng-Po
Abstract: The article presents a study on the presence of nasopharynx biofilms among patients with nasopharyngeal cancer (NPC), osteoradionecrosis (ORN), and patients with NPC but no ORN. It says that 27 NPC, 15 ORN, and 12 without ORN patients had receive radiotherapy and were evaluated by fluorescence microscopy to determine biofilms formation. It concludes that the presence of biofilms, which are common with NPC patients with ORN, contribute to the resistance of antibiotic treatment.
Subjects: BIOFILMS; NASOPHARYNX cancer patients; OSTEORADIONECROSIS; RADIOTHERAPY; FLUORESCENCE microscopy; ANTIBIOTIC prophylaxis; THERAPEUTICS
Publication: Otolaryngology-Head & Neck Surgery, 2013, Vol 148, Issue 4, p633
ISSN: 0194-5998
Publication type: Academic Journal
DOI: 10.1177/0194599812474971

Biofilm Formations in Nasopharyngeal Tissues of Patients with Nasopharyngeal Osteoradionecrosis.

Tsai, Yih-Jeng; Lin, Yu-Chi; Wu, Wen-Bin; Chiu, Po-Han; Lin, Brian J.; Hao, Sheng-Po