Works matching IS 00912700 AND DT 2012 AND VI 52

Results: 243

Don’t Get Boxed In: Commentary on the Visual Inspection Practices to Assess Exposure-Response Relationships From Binary Clinical Variables.

Published in:

2012

By:

Mehrotra, Shailly;
Florian, Jeffry;
Gobburu, Jogarao

Publication type:

Journal Article

Tamsulosin Exposure Is Significantly Increased by the CYP2D610/10 Genotype.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1934, doi. 10.1177/0091270011432168

By:

Choi, Chang-Ik;
Bae, Jung-Woo;
Jang, Choon-Gon;
Lee, Seok-Yong

Publication type:

Article

Brivaracetam Disposition in Renal Impairment.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1927, doi. 10.1177/0091270011431457

By:

Sargentini-Maier, Maria Laura;
Sokalski, Antoni;
Boulanger, Pierre;
Jacobs, Tom;
Stockis, Armel

Publication type:

Article

Population Pharmacokinetics of Rituximab in Patients With Chronic Lymphocytic Leukemia.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1918, doi. 10.1177/0091270011430506

By:

Li, Jing;
Zhi, Jianguo;
Wenger, Michael;
Valente, Nancy;
Dmoszynska, Anna;
Robak, Tadeusz;
Mangat, Ranvir;
Joshi, Amita;
Visich, Jennifer

Publication type:

Article

Computerized Extraction of Electrocardiograms From Continuous 12-Lead Holter Recordings Reduces Measurement Variability in a Thorough QT Study.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1891, doi. 10.1177/0091270011430505

By:

George, Samuel;
Rodriguez, Ignacio;
Ipe, David;
Sager, Philip T.;
Gussak, Ihor;
Vajdic, Branislav

Publication type:

Article

Dosing Rationale for Liraglutide in Type 2 Diabetes Mellitus: A Pharmacometric Assessment.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1815, doi. 10.1177/0091270011430504

By:

Ingwersen, Steen H.;
Khurana, Manoj;
Madabushi, Rajanikanth;
Watson, Estelle;
Jonker, Daniël M.;
Le Thi, Tu Duyen;
Jacobsen, Lisbeth V.;
Tornøe, Christoffer W.

Publication type:

Article

Don’t Get Boxed In: Commentary on the Visual Inspection Practices to Assess Exposure-Response Relationships From Binary Clinical Variables.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1912, doi. 10.1177/0091270011429568

By:

Mehrotra, Shailly;
Florian, Jeffry;
Gobburu, Jogarao

Publication type:

Article

Pregnancy Outcome Following Exposure to Topical Retinoids: A Multicenter Prospective Study.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1844, doi. 10.1177/0091270011429566

By:

Panchaud, Alice;
Csajka, Chantal;
Merlob, Paul;
Schaefer, Christof;
Berlin, Maya;
De Santis, Marco;
Vial, Thierry;
Ieri, Alessandra;
Malm, Heli;
Eleftheriou, Georgios;
Stahl, Bracha;
Rousso, Philippe;
Winterfeld, Ursula;
Rothuizen, Laura E.;
Buclin, Thierry

Publication type:

Article

Teaching Clinical Pharmacology Using Team-Based Learning: A Comparison Between Third- and Fourth-Year Medical Students.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1806, doi. 10.1177/0091270011428986

By:

Bou Akl, Imad;
Ghaddar, Fatima;
Sabra, Ramzi;
Parmelee, Dean;
Simaan, Joseph A.;
Kanafani, Zeina A.;
Zgheib, Nathalie K.

Publication type:

Article

Pharmacodynamic Effects of Steady-State Fingolimod on Antibody Response in Healthy Volunteers: A 4-Week, Randomized, Placebo-Controlled, Parallel-Group, Multiple-Dose Study.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1879, doi. 10.1177/0091270011427908

By:

Boulton, Craig;
Meiser, Karin;
David, Olivier J.;
Schmouder, Robert

Publication type:

Article

Efficacy and Safety of Vernakalant in Recent-Onset Atrial Fibrillation After the European Medicines Agency Approval: Systematic Review and Meta-Analysis.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1872, doi. 10.1177/0091270011426876

By:

Buccelletti, Francesco;
Iacomini, Paolo;
Botta, Gianfranco;
Marsiliani, Davide;
Carroccia, Annarita;
Gentiloni Silveri, Nicolò;
Franceschi, Francesco

Publication type:

Article

Developmental Pharmacokinetic Changes of Lamivudine in Infants and Children.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1824, doi. 10.1177/0091270011426563

By:

Tremoulet, Adriana H.;
Nikanjam, Mina;
Cressey, Tim R.;
Chokephaibulkit, Kulkanya;
McKinney, Ross;
Mirochnick, Mark;
Capparelli, Edmund V.

Publication type:

Article

Authors’ Response.

Published in:

2012

By:

Wohlfarth, Ariane;
Naue, Jana;
Lutz-Bonengel, Sabine;
Dresen, Sebastian;
Auwärter, Volker

Publication type:

Journal Article

Highlights From a Recent BIO Survey on Therapeutic Protein–Drug Interactions.

Published in:

2012

By:

Lloyd, Peter;
Zhou, Honghui;
Theil, Frank-Peter;
Kakkar, Tarundeep;
Nestorov, Ivan;
Roberts, Stanley A.

Publication type:

Journal Article

Disposition of Atorvastatin, Rosuvastatin, and Simvastatin in Oatp1b2−/− Mice and Intraindividual Variability in Human Subjects.

Published in:

2012

By:

DeGorter, M. K.;
Urquhart, B. L.;
Gradhand, U.;
Tirona, R. G.;
Kim, R. B.

Publication type:

Journal Article

Efficacy, Safety, and Tolerability of Aliskiren Monotherapy Administered With a Light Meal in Elderly Hypertensive Patients: A Randomized, Double-Blind, Placebo-Controlled, Dose-Response Evaluation Study.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1901, doi. 10.1177/0091270011426432

By:

Villa, Giuseppe;
Le Breton, Stephanie;
Ibram, Ghionul;
Keefe, Deborah L.

Publication type:

Article

Identification of the Mechanism of Action of a Glucokinase Activator From Oral Glucose Tolerance Test Data in Type 2 Diabetic Patients Based on an Integrated Glucose-Insulin Model.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1861, doi. 10.1177/0091270011422231

By:

Jauslin, Petra M.;
Karlsson, Mats O.;
Frey, Nicolas

Publication type:

Article

Author’s Response to Comments by Hu et al.

Published in:

2012

By:

Li, Yan-peng;
Zhang, Li-rong;
Jia, Min;
Hu, Xiang-Jie

Publication type:

Journal Article

Comparison of Changes in the Lipid Profile of Postmenopausal Women With Early Stage Breast Cancer Treated With Exemestane or Letrozole.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1852, doi. 10.1177/0091270011424153

By:

Bell, Lauren Nicole;
Nguyen, Anne Thi Phuong;
Li, Lang;
Desta, Zeruesenay;
Henry, N. Lynn;
Hayes, Daniel F.;
Wolff, Antonio C.;
Stearns, Vered;
Storniolo, Anna Maria;
Flockhart, David A.

Publication type:

Article

Clinical Pharmacokinetics and Drug-Drug Interactions of Endothelin Receptor Antagonists in Pulmonary Arterial Hypertension.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1784, doi. 10.1177/0091270011423662

By:

Venitz, Jürgen;
Zack, Julia;
Gillies, Hunter;
Allard, Martine;
Regnault, Jean;
Dufton, Christopher

Publication type:

Article

A Simultaneous D-Optimal Designed Study for Population Pharmacokinetic Analyses of Mycophenolic Acid and Tacrolimus Early After Renal Transplantation.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 12, p. 1833, doi. 10.1177/0091270011423661

By:

Musuamba, Flora Tshinanu;
Mourad, Michel;
Haufroid, Vincent;
Demeyer, Martine;
Capron, Arnaud;
Delattre, Isabelle K.;
Delaruelle, Frederic;
Wallemacq, Pierre;
Verbeeck, Roger Karel

Publication type:

Article

Comments on “CYP3AP1*3 Allele Is Associated With Lipid-Lowering Efficacy of Simvastatin and Atorvastatin in Chinese Women”.

Published in:

2012

By:

Hu, Miao;
Mak, Valiant W.L.;
Tomlinson, Brian

Publication type:

Journal Article

Author’s Response to Comments by Hu et al.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1770, doi. 10.1177/0091270012436559

By:

Li, Yan-peng;
Zhang, Li-rong;
Jia, Min;
Hu, Xiang-Jie

Publication type:

Article

Validating Phenotyping Cocktails: More Work Needs to Be Done.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1772, doi. 10.1177/0091270011436346

By:

Ma, Joseph D.;
Nafziger, Anne N.;
Bertino, Joseph S.

Publication type:

Article

Authors’ Response.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1774, doi. 10.1177/0091270011436345

By:

Wohlfarth, Ariane;
Naue, Jana;
Lutz-Bonengel, Sabine;
Dresen, Sebastian;
Auwärter, Volker

Publication type:

Article

Modulation of Lymphangiogenesis: A New Target for Aspirin and Other Nonsteroidal Anti-inflammatory Agents? A Systematic Review.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1749, doi. 10.1177/0091270011431066

By:

Yiannakopoulou, Eugenia

Publication type:

Article

Probable Dalteparin-Induced Hepatotoxicity in a Man With Alpha-1-Antitrypsin Deficiency.

Published in:

2012

By:

Levinson, Pauline;
Glaumann, Hans;
Söderberg, Mårten

Publication type:

Case Study

Evaluation of the Effects of a High-Fat Meal on the Oral Bioavailability of a Single Dose of Preladenant in Healthy Subjects.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1698, doi. 10.1177/0091270011428321

By:

Cutler, David L.;
Tendolkar, Amol;
Grachev, Igor D.

Publication type:

Article

Population Pharmacokinetics of Valproic Acid in Pediatric Patients With Epilepsy: Considerations for Dosing Spinal Muscular Atrophy Patients.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1676, doi. 10.1177/0091270011428138

By:

Williams, Jason H.;
Jayaraman, Bhuvaneswari;
Swoboda, Kathryn J.;
Barrett, Jeffrey S.

Publication type:

Article

Influence of SLCO1B1 Polymorphisms on the Drug-Drug Interaction Between Darunavir/Ritonavir and Pravastatin.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1725, doi. 10.1177/0091270011427907

By:

Aquilante, Christina L.;
Kiser, Jennifer J.;
Anderson, Peter L.;
Christians, Uwe;
Kosmiski, Lisa A.;
Daily, Elizabeth B.;
Hoffman, Keith L.;
Hopley, Charles W.;
Predhomme, Julie A.;
Schniedewind, Bjorn;
Sidhom, Maha S.

Publication type:

Article

Pharmacokinetics of Single-Dose Doripenem in Adults With Cystic Fibrosis.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1645, doi. 10.1177/0091270011427564

By:

Cirillo, Iolanda;
Vaccaro, Nicole;
Redman, Rebecca;
Black, Philip L.;
Kearns, Gregory L.

Publication type:

Article

A Limited Sampling Schedule to Estimate Mycophenolic Acid Area Under the Concentration-Time Curve in Hematopoietic Cell Transplantation Recipients.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1654, doi. 10.1177/0091270011429567

By:

Li, Hong;
Mager, Donald E.;
Bemer, Meagan J.;
Salinger, David H.;
Vicini, Paolo;
Sandmaier, Brenda M.;
Nash, Richard;
McCune, Jeannine S.

Publication type:

Article

Suspected Clonazepam-Induced Bullous Dermatosis in a Patient With Respiratory Failure.

Published in:

2012

By:

Lee, Ming-Chia;
Su, Chiu-Ping;
Wang, Chun-Hua;
Lan, Chou-Chin;
Wu, Ta-Wei

Publication type:

Case Study

Population Pharmacokinetic and Pharmacodynamic Model-Based Comparability Assessment of a Recombinant Human Epoetin Alfa and the Biosimilar HX575.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1624, doi. 10.1177/0091270011421911

By:

Yan, Xiaoyu;
Lowe, Philip J.;
Fink, Martin;
Berghout, Alexander;
Balser, Sigrid;
Krzyzanski, Wojciech

Publication type:

Article

Highlights From a Recent BIO Survey on Therapeutic Protein–Drug Interactions.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1755, doi. 10.1177/0091270011424144

By:

Lloyd, Peter;
Zhou, Honghui;
Theil, Frank-Peter;
Kakkar, Tarundeep;
Nestorov, Ivan;
Roberts, Stanley A.

Publication type:

Article

Ovulation-Inhibiting Effects of Dienogest in a Randomized, Dose-Controlled Pharmacodynamic Trial of Healthy Women.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1704, doi. 10.1177/0091270011423664

By:

Klipping, Christine;
Duijkers, Ingrid;
Remmers, Ageeth;
Faustmann, Thomas;
Zurth, Christian;
Klein, Stefan;
Schuett, Barbara

Publication type:

Article

Disposition of Atorvastatin, Rosuvastatin, and Simvastatin in Oatp1b2−/− Mice and Intraindividual Variability in Human Subjects.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1689, doi. 10.1177/0091270011422815

By:

DeGorter, M. K.;
Urquhart, B. L.;
Gradhand, U.;
Tirona, R. G.;
Kim, R. B.

Publication type:

Article

No Pharmacokinetic Interaction Between Lacosamide and Valproic Acid in Healthy Volunteers.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1739, doi. 10.1177/0091270011426875

By:

Cawello, Willi;
Bonn, Rainer

Publication type:

Article

Pharmacokinetics of the Soluble Guanylate Cyclase Activator Cinaciguat in Individuals With Hepatic Impairment.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1714, doi. 10.1177/0091270011426143

By:

Frey, Reiner;
Scheerans, Christian;
Blunck, Martin;
Mück, Wolfgang;
Gnoth, Mark Jean;
Unger, Sigrun;
Schmidt, Anja;
Wensing, Georg

Publication type:

Article

Comments on “CYP3AP1*3 Allele Is Associated With Lipid-Lowering Efficacy of Simvastatin and Atorvastatin in Chinese Women”.

Published in:

2012

By:

Hu, Miao;
Mak, Valiant W.L.;
Tomlinson, Brian

Publication type:

Letter

Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.

Published in:

2012

By:

Skarke, Carsten;
Kuczka, Karina;
Tausch, Lars;
Werz, Oliver;
Rossmanith, Tanja;
Barrett, Jeffrey S.;
Harder, Sebastian;
Holtmeier, Wolfgang;
Schwarz, Joachim A.

Publication type:

Journal Article

Multiple-Dose Safety, Pharmacokinetics, and Pharmacodynamics of the µ-Opioid Receptor Inverse Agonist GSK1521498.

Published in:

2012

By:

Nathan, Pradeep J.;
Bush, Mark A.;
Tao, Wenli X.;
Koch, Annelize;
Davies, Kirsty M.;
Maltby, Kay;
O’Neill, Barry V.;
Napolitano, Antonella;
Skeggs, Andrew L.;
Brooke, Allison C.;
Richards, Duncan B.;
Williams, Pauline M.;
Bullmore, Edward T.

Publication type:

Journal Article

Population Pharmacokinetics of Unbound Mycophenolic Acid in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplantation.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 11, p. 1665, doi. 10.1177/0091270011422814

By:

Kim, Hyewon;
Long-Boyle, Janel;
Rydholm, Nancy;
Orchard, Paul J.;
Tolar, Jakub;
Smith, Angela R.;
Jacobson, Pamala;
Brundage, Richard

Publication type:

Article

A Step Toward More Accurate Dosing for Mercaptopurine in Childhood Acute Lymphoblastic Leukemia.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1610, doi. 10.1177/0091270011423663

By:

Mulla, Hussain;
Leary, Andrew;
White, Peter;
Pandya, Hitesh C.

Publication type:

Article

Opioids, QTc Prolongation, and Torsades.

Published in:

2012

By:

Kurt, Thomas L.

Publication type:

Letter

Food Effect on Bioavailability of Modified-Release Trimetazidine Tablets.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1535, doi. 10.1177/0091270011422813

By:

Ozbay, Latif;
Unal, Durisehvar Ozer;
Erol, Dilek

Publication type:

Article

Clarification on Precision Criteria to Derive Sample Size When Designing Pediatric Pharmacokinetic Studies.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1601, doi. 10.1177/0091270011422812

By:

Wang, Yaning;
Jadhav, Pravin R.;
Lala, Mallika;
Gobburu, Jogarao V.

Publication type:

Article

Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1592, doi. 10.1177/0091270011422811

By:

Skarke, Carsten;
Kuczka, Karina;
Tausch, Lars;
Werz, Oliver;
Rossmanith, Tanja;
Barrett, Jeffrey S.;
Harder, Sebastian;
Holtmeier, Wolfgang;
Schwarz, Joachim A.

Publication type:

Article

Pharmacodynamics, Pharmacokinetics, and Safety of AM211: A Novel and Potent Antagonist of the Prostaglandin D2 Receptor Type 2.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1482, doi. 10.1177/0091270011421912

By:

Bain, G.;
King, C. D.;
Brittain, J.;
Hartung, J. P.;
DeArmond, I.;
Stearns, B.;
Truong, Y. P.;
Hutchinson, J. H.;
Evans, J. F.;
Holme, K.

Publication type:

Article

Multiple-Dose Safety, Pharmacokinetics, and Pharmacodynamics of the µ-Opioid Receptor Inverse Agonist GSK1521498.

Published in:

Journal of Clinical Pharmacology, 2012, v. 52, n. 10, p. 1456, doi. 10.1177/0091270011421785

By:

Nathan, Pradeep J.;
Bush, Mark A.;
Tao, Wenli X.;
Koch, Annelize;
Davies, Kirsty M.;
Maltby, Kay;
O’Neill, Barry V.;
Napolitano, Antonella;
Skeggs, Andrew L.;
Brooke, Allison C.;
Richards, Duncan B.;
Williams, Pauline M.;
Bullmore, Edward T.

Publication type:

Article