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Results: 53

A conversation with Jeffrey M. Friedman by Ushma S. Neill.
Published in:
2013
By:
- Friedman, Jeffrey M
Publication type:
Historical Material
β4 Integrin signaling induces expansion of prostate tumor progenitors.
Published in:
2013
By:
- Yoshioka, Toshiaki;
- Otero, Javier;
- Chen, Yu;
- Kim, Young-Mi;
- Koutcher, Jason A;
- Satagopan, Jaya;
- Reuter, Victor;
- Carver, Brett;
- de Stanchina, Elisa;
- Enomoto, Katsuhiko;
- Greenberg, Norman M;
- Scardino, Peter T;
- Scher, Howard I;
- Sawyers, Charles L;
- Giancotti, Filippo G
Publication type:
journal article
Coal tar induces AHR-dependent skin barrier repair in atopic dermatitis.
Published in:
2013
By:
- van den Bogaard, Ellen H;
- Bergboer, Judith G M;
- Vonk-Bergers, Mieke;
- van Vlijmen-Willems, Ivonne M J J;
- Hato, Stanleyson V;
- van der Valk, Pieter G M;
- Schröder, Jens Michael;
- Joosten, Irma;
- Zeeuwen, Patrick L J M;
- Schalkwijk, Joost
Publication type:
journal article
Old King coal - molecular mechanisms underlying an ancient treatment for atopic eczema.
Published in:
2013
By:
- McLean, W H Irwin;
- Irvine, Alan D
Publication type:
journal article
MicroRNA-374a activates Wnt/β-catenin signaling to promote breast cancer metastasis.
Published in:
2013
By:
- Cai, Junchao;
- Guan, Hongyu;
- Fang, Lishan;
- Yang, Yi;
- Zhu, Xun;
- Yuan, Jie;
- Wu, Jueheng;
- Li, Mengfeng
Publication type:
journal article
CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.
Published in:
2013
By:
- Slight, Samantha R;
- Rangel-Moreno, Javier;
- Gopal, Radha;
- Lin, Yinyao;
- Fallert Junecko, Beth A;
- Mehra, Smriti;
- Selman, Moises;
- Becerril-Villanueva, Enrique;
- Baquera-Heredia, Javier;
- Pavon, Lenin;
- Kaushal, Deepak;
- Reinhart, Todd A;
- Randall, Troy D;
- Khader, Shabaana A
Publication type:
journal article
iRHOM2 takes control of rheumatoid arthritis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67548
By:
- Lichtenthaler, Stefan F.
Publication type:
Article
Why stress is BAD for cancer patients.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67887
By:
- Nagaraja, Archana S.;
- Armaiz-Pena, Guillermo N.;
- Lutgendorf, Susan K.;
- Sood, Anil K.
Publication type:
Article
Cancer therapy combination: green tea and a phosphodiesterase 5 inhibitor?
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67589
By:
- Yang, Chung S.;
- Hong Wang
Publication type:
Article
B4 androgen ablation: attacking the prostate cancer stem cell.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67460
By:
- Wicha, Max S.
Publication type:
Article
Nucleocytoplasmic connections and deafness.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67454
By:
- Worman, Howard J.;
- Segil, Neil
Publication type:
Article
Old King Coal -- molecular mechanisms underlying an ancient treatment for atopic eczema.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67438
By:
- McLean, W. H. Irwin;
- Irvine, Alan D.
Publication type:
Article
Multiple functions of a glioblastoma fusion oncogene.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI67658
By:
- Babic, Ivan;
- Mischel, Paul S.
Publication type:
Article
Ubiquitylation and the pathogenesis of hypertension.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 934, doi. 10.1172/JCI66882
By:
- Ellison, David H.
Publication type:
Article
Corrigendum.
Published in:
2013
Publication type:
Correction Notice
Erratum.
Published in:
2013
Publication type:
Correction Notice
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 928, doi. 10.1172/JCI66168
By:
- Issuree, Priya Darshinee A.;
- Maretzky, Thorsten;
- McIlwain, David R.;
- Monette, Sébastien;
- Qing, Xiaoping;
- Lang, Philipp A.;
- Swendeman, Steven L.;
- Park-Min, Kyung-Hyun;
- Binder, Nikolaus;
- Kalliolias, George D.;
- Yarilina, Anna;
- Horiuchi, Keisuke;
- Ivashkiv, Lionel B.;
- Mak, Tak W.;
- Salmon, Jane E.;
- Blobel, Carl P.
Publication type:
Article
Platelet ITAM signaling is critical for vascular integrity in inflammation.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 908, doi. 10.1172/JCI65154
By:
- Boulaftali, Yacine;
- Hess, Paul R.;
- Getz, Todd M.;
- Cholka, Agnieszka;
- Stolla, Moritz;
- Mackman, Nigel;
- Owens III, A. Phillip;
- Ware, Jerry;
- Kahn, Mark L.;
- Bergmeier, Wolfgang
Publication type:
Article
Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 903, doi. 10.1172/JCI66227
By:
- Klatt, Nichole R.;
- Canary, Lauren A.;
- Xiaoyong Sun;
- Vinton, Carol L.;
- Funderburg, Nicholas T.;
- Morcock, David R.;
- Quiñones, Mariam;
- Deming, Clayton B.;
- Perkins, Molly;
- Hazuda, Daria J.;
- Miller, Michael D.;
- Lederman, Michael M.;
- Segre, Julie A.;
- Lifson, Jeffrey D.;
- Haddad, Elias K.;
- Estes, Jacob D.;
- Brenchley, Jason M.
Publication type:
Article
Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 887, doi. 10.1172/JCI65647
By:
- Gandhirajan, Rajesh Kumar;
- Meng, Shu;
- Chandramoorthy, Harish C.;
- Mallilankaraman, Karthik;
- Ju Chen;
- Koch, Walter J.;
- Hong Wang;
- Soboloff, Jonathan;
- Gill, Donald L.;
- Madesh, Muniswamy
Publication type:
Article
Behavioral stress accelerates prostate cancer development in mice.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 874, doi. 10.1172/JCI63324
By:
- Hassan, Sazzad;
- Karpova, Yelena;
- Baiz, Daniele;
- Yancey, Dana;
- Pullikuth, Ashok;
- Flores, Anabel;
- Register, Thomas;
- Cline, J. Mark;
- D'Agostino Jr., Ralph;
- Danial, Nika;
- Robert Datta, Sandeep;
- Kulik, George
Publication type:
Article
Dynamic visualization of RANKL and Th17-mediated osteoclast function.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 866, doi. 10.1172/JCI65054
By:
- Kikuta, Junichi;
- Wada, Yoh;
- Kowada, Toshiyuki;
- Ze Wang;
- Sun-Wada, Ge-Hong;
- Nishiyama, Issei;
- Mizukami, Shin;
- Maiya, Nobuhiko;
- Yasuda, Hisataka;
- Kumanogoh, Atsushi;
- Kikuchi, Kazuya;
- Germain, Ronald N.;
- Ishii, Masaru
Publication type:
Article
The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 855, doi. 10.1172/JCI67144
By:
- Parker, Brittany C.;
- Annala, Matti J.;
- Cogdell, David E.;
- Granberg, Kirsi J.;
- Yan Sun;
- Ping Ji;
- Xia Li;
- Joy Gumin;
- Hong Zheng;
- Limei Hu;
- Yli-Harja, Olli;
- Haapasalo, Hannu;
- Visakorpi, Tapio;
- Xiuping Liu;
- Liu, Chang-gong;
- Sawaya, Raymond;
- Fuller, Gregory N.;
- Kexin Chen;
- Lang, Frederick F.;
- Nykter, Matti
Publication type:
Article
Specialized role of migratory dendritic cells in peripheral tolerance induction.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 844, doi. 10.1172/JCI65260
By:
- Idoyaga, Juliana;
- Fiorese, Christopher;
- Zbytnuik, Lori;
- Lubkin, Ashira;
- Miller, Jennifer;
- Malissen, Bernard;
- Mucida, Daniel;
- Merad, Miriam;
- Steinman, Ralph M.
Publication type:
Article
Liver acid sphingomyelinase inhibits growth of metastatic colon cancer.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 834, doi. 10.1172/JCI65188
By:
- Osawa, Yosuke;
- Suetsugu, Atsushi;
- Matsushima-Nishiwaki, Rie;
- Yasuda, Ichiro;
- Saibara, Toshiji;
- Moriwaki, Hisataka;
- Seishima, Mitsuru;
- Kozawa, Osam
Publication type:
Article
Regulation of dendritic cell activation by microRNA let-7c and BLIMP1.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 823, doi. 10.1172/JCI64712
By:
- Kim, Sun Jung;
- Gregersen, Peter K.;
- Diamond, Betty
Publication type:
Article
Spironolactone ameliorates PIT1-dependent vascular osteoinduction in klotho-hypomorphic mice.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 812, doi. 10.1172/JCI64093
By:
- Voelkl, Jakob;
- Alesutan, Ioana;
- Leibrock, Christina B.;
- Quintanilla-Martinez, Leticia;
- Kuhn, Volker;
- Feger, Martina;
- Mia, Sobuj;
- Ahmed, Mohamed S.E.;
- Rosenblatt, Kevin P.;
- Kuro-o, Makoto;
- Lang, Florian
Publication type:
Article
Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 800, doi. 10.1172/JCI60139
By:
- Spindler, Volker;
- Rötzer, Vera;
- Dehner, Carina;
- Kempf, Bettina;
- Gliem, Martin;
- Radeva, Mariya;
- Hartlieb, Eva;
- Harms, Gregory S.;
- Schmidt, Enno;
- Waschke, Jens
Publication type:
Article
67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 787, doi. 10.1172/JCI64768
By:
- Kumazoe, Motofumi;
- Sugihara, Kaori;
- Tsukamoto, Shuntaro;
- Huang, Yuhui;
- Tsurudome, Yukari;
- Suzuki, Takashi;
- Suemasu, Yumi;
- Ueda, Naoki;
- Yamashita, Shuya;
- Kim, Yoonhee;
- Yamada, Koji;
- Tachibana, Hirofumi
Publication type:
Article
Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 782, doi. 10.1172/JCI65863
By:
- Ji Hae Seo;
- Miyamoto, Nobukazu;
- Hayakawa, Kazuhide;
- Pham, Loc-Duyen D.;
- Maki, Takakuni;
- Ayata, Cenk;
- Kim, Kyu-Won;
- Lo, Eng H.;
- Arai, Ken
Publication type:
Article
mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 767, doi. 10.1172/JCI65086
By:
- Thiem, Stefan;
- Pierce, Thomas P.;
- Palmieri, Michelle;
- Putoczki, Tracy L.;
- Buchert, Michael;
- Preaudet, Adele;
- Farid, Ryan O.;
- Love, Chris;
- Catimel, Bruno;
- Lei, Zhengdeng;
- Rozen, Steve;
- Gopalakrishnan, Veena;
- Schaper, Fred;
- Hallek, Michael;
- Boussioutas, Alex;
- Tan, Patrick;
- Jarnicki, Andrew;
- Ernst, Matthias
Publication type:
Article
Loss of SPARC in bladder cancer enhances carcinogenesis and progression.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 751, doi. 10.1172/JCI64782
By:
- Said, Neveen;
- Frierson, Henry F.;
- Sanchez-Carbayo, Marta;
- Brekken, Rolf A.;
- Theodorescu, Dan
Publication type:
Article
The LINC complex is essential for hearing.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 740, doi. 10.1172/JCI66911
By:
- Horn, Henning F.;
- Brownstein, Zippora;
- Lenz, Danielle R.;
- Shivatzki, Shaked;
- Dror, Amiel A.;
- Dagan-Rosenfeld, Orit;
- Friedman, Lilach M.;
- Roux, Kyle J.;
- Kozlov, Serguei;
- Jeang, Kuan-Teh;
- Frydman, Moshe;
- Burke, Brian;
- Stewart, Colin L.;
- Avraham, Karen B.
Publication type:
Article
KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 727, doi. 10.1172/JCI64535
By:
- Tzatsos, Alexandros;
- Paskaleva, Polina;
- Ferrari, Francesco;
- Deshpande, Vikram;
- Stoykova, Svetlana;
- Contino, Gianmarco;
- Wong, Kwok-Kin;
- Fei Lan;
- Trojer, Patrick;
- Park, Peter J.;
- Bardeesy, Nabeel
Publication type:
Article
CXCR5<sup>+</sup> T helper cells mediate protective immunity against tuberculosis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 712, doi. 10.1172/JCI65728
By:
- Slight, Samantha R.;
- Rangel-Moreno, Javier;
- Gopal, Radha;
- Yinyao Lin;
- Fallert Junecko, Beth A.;
- Mehra, Smriti;
- Selman, Moises;
- Becerril-Villanueva, Enrique;
- Baquera-Heredia, Javier;
- Pavon, Lenin;
- Kaushal, Deepak;
- Reinhart, Todd A.;
- Randall, Troy D.;
- Khader, Shabaana A.
Publication type:
Article
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 700, doi. 10.1172/JCI62236
By:
- Couturier-Maillard, Aurélie;
- Secher, Thomas;
- Rehman, Ateequr;
- Normand, Sylvain;
- Arcangelis, Adèle De;
- Haesler, Robert;
- Huot, Ludovic;
- Grandjean, Teddy;
- Bressenot, Aude;
- Delanoye-Crespin, Anne;
- Gaillot, Olivier;
- Schreiber, Stefan;
- Lemoine, Yves;
- Ryffe, Bernhard;
- Hot, David;
- Nùñez, Gabriel;
- Chen, Grace;
- Rosenstie, Philip;
- Chamaillard, Mathias
Publication type:
Article
ß4 Integrin signaling induces expansion of prostate tumor progenitors.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 682, doi. 10.1172/JCI60720
By:
- Yoshioka, Toshiaki;
- Otero, Javier;
- Yu Chen;
- Kim, Young-Mi;
- Koutcher, Jason A.;
- Satagopan, Jaya;
- Reuter, Victor;
- Carver, Brett;
- Stanchina, Elisa de;
- Enomoto, Katsuhiko;
- Greenberg, Norman M.;
- Scardino, Peter T.;
- Scher, Howard I.;
- Sawyers, Charles L.;
- Giancotti, Filippo G.
Publication type:
Article
Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 666, doi. 10.1172/JCI64840
By:
- Lotinun, Sutada;
- Kiviranta, Riku;
- Matsubara, Takuma;
- Alzate, Jorge A.;
- Neff, Lynn;
- Lüth, Anja;
- Koskivirta, Ilpo;
- Kleuser, Burkhard;
- Vacher, Jean;
- Vuorio, Eero;
- Horne, William C.;
- Baron, Roland
Publication type:
Article
Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 657, doi. 10.1172/JCI61110
By:
- Ronzaud, Caroline;
- Loffing-Cueni, Dominique;
- Hausel, Pierrette;
- Debonneville, Anne;
- Malsure, Sumedha Ram;
- Fowler-Jaeger, Nicole;
- Boase, Natasha A.;
- Perrier, Romain;
- Maillard, Marc;
- Baoli Yang;
- Stokes, John B.;
- Koesters, Robert;
- Kumar, Sharad;
- Hummler, Edith;
- Loffing, Johannes;
- Staub, Olivier
Publication type:
Article
Deimination restores inner retinal visual function in murine demyelinating disease.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 646, doi. 10.1172/JCI64811
By:
- Enriquez-Algeciras, Mabel;
- Di Ding;
- Mastronardi, Fabrizio G.;
- Marc, Robert E.;
- Porciatti, Vittorio;
- Bhattacharya, Sanjoy K.
Publication type:
Article
Hepatitis B virus X protein represses miRNA-148a to enhance tumorigenesis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 630, doi. 10.1172/JCI64265
By:
- Xiaojie Xu;
- Zhongyi Fan;
- Lei Kang;
- Juqiang Han;
- Chengying Jiang;
- Xiaofei Zheng;
- Ziman Zhu;
- Huabo Jiao;
- Jing Lin;
- Kai Jiang;
- Lihua Ding;
- Hao Zhang;
- Long Cheng;
- Hanjiang Fu;
- Yi Song;
- Ying Jiang;
- Jiahong Liu;
- Rongfu Wang;
- Nan Du;
- Qinong Ye
Publication type:
Article
Patients with type 1 diabetes exhibit altered cerebral metabolism during hypoglycemia.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 623, doi. 10.1172/JCI62742
By:
- van de Ven, Kim C.C.;
- Tack, Cees J.;
- Heerschap, Arend;
- van der Graaf, Marinette;
- de Galan, Bastiaan E.
Publication type:
Article
Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 611, doi. 10.1172/JCI39920
By:
- Porporato, Paolo E.;
- Filigheddu, Nicoletta;
- Reano, Simone;
- Ferrara, Michele;
- Angelino, Elia;
- Gnocchi, Viola F.;
- Prodam, Flavia;
- Ronchi, Giulia;
- Fagoonee, Sharmila;
- Fornaro, Michele;
- Chianale, Federica;
- Baldanzi, Gianluca;
- Surico, Nicola;
- Sinigaglia, Fabiola;
- Perroteau, Isabelle;
- Smith, Roy G.;
- Sun, Yuxiang;
- Geuna, Stefano;
- Graziani, Andrea
Publication type:
Article
EWS/ATF1 expression induces sarcomas from neural crest-derived cells in mice.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 600, doi. 10.1172/JCI63572
By:
- Yamada, Kazunari;
- Ohno, Takatoshi;
- Aoki, Hitomi;
- Semi, Katsunori;
- Watanabe, Akira;
- Moritake, Hiroshi;
- Shiozawa, Shunichi;
- Kunisada, Takahiro;
- Kobayashi, Yukiko;
- Toguchida, Junya;
- Shimizu, Katsuji;
- Hara, Akira;
- Yamada, Yasuhiro
Publication type:
Article
Superior T memory stem cell persistence supports long-lived T cell memory.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 594, doi. 10.1172/JCI66327
By:
- Lugli, Enrico;
- Dominguez, Maria H.;
- Gattinoni, Luca;
- Chattopadhyay, Pratip K.;
- Bolton, Diane L.;
- Song, Kaimei;
- Klatt, Nichole R.;
- Brenchley, Jason M.;
- Vaccari, Monica;
- Gostick, Emma;
- Price, David A.;
- Waldmann, Thomas A.;
- Restifo, Nicholas P.;
- Franchini, Genoveffa;
- Roederer, Mario
Publication type:
Article
An obligate cell-intrinsic function for CD28 in Tregs.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 580, doi. 10.1172/JCI65013
By:
- Ruan Zhang;
- Alexandria Huynh;
- Whitcher, Gregory;
- JiHoon Chang;
- Maltzman, Jonathan S.;
- Turka, Laurence A.
Publication type:
Article
MicroRNA-374a activates Wnt/ß-catenin signaling to promote breast cancer metastasis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 566, doi. 10.1172/JCI65871
By:
- Junchao Cai;
- Hongyu Guan;
- Lishan Fang;
- Yi Yang;
- Xun Zhu;
- Jie Yuan;
- Jueheng Wu;
- Mengfeng Li
Publication type:
Article
Linking endothelial dysfunction with endothelial cell activation.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 540, doi. 10.1172/JCI66843
By:
- Liao, James K.
Publication type:
Article
Alzheimer's disease and insulin resistance: translating basic science into clinical applications.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 531, doi. 10.1172/JCI64595
By:
- Felice, Fernanda G. De
Publication type:
Article
A conversation with Jeffrey M. Friedman.
Published in:
2013
Publication type:
Interview