Works matching IS 00219738 AND DT 2012 AND VI 122 AND IP 5

Results: 50

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1791, doi. 10.1172/JCI60975

By:

Harre, Ulrike;
Georgess, Dan;
Bang, Holger;
Bozec, Aline;
Axmann, Roland;
Ossipova, Elena;
Jakobsson, Per-Johan;
Baum, Wolfgang;
Nimmerjahn, Falk;
Szarka, Eszter;
Sarmay, Gabriella;
Krumbholz, Grit;
Neumann, Elena;
Toes, Rene;
Scherer, Hans-Ulrich;
Catrina, Anca Irinel;
Klareskog, Lars;
Jurdic, Pierre;
Schett, Georg

Publication type:

Article

Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice.

Published in:

2012

By:

Zhang Y;
Breevoort SR;
Angdisen J;
Fu M;
Schmidt DR;
Holmstrom SR;
Kliewer SA;
Mangelsdorf DJ;
Schulman IG;
Zhang, Yuan;
Breevoort, Sarah R;
Angdisen, Jerry;
Fu, Mingui;
Schmidt, Daniel R;
Holmstrom, Sam R;
Kliewer, Steven A;
Mangelsdorf, David J;
Schulman, Ira G

Publication type:

journal article

Corrigendum.

Published in:: 2012
Publication type:: Correction Notice

Corrigendum.

Published in:: 2012
Publication type:: Correction Notice

Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1832, doi. 10.1172/JCI58976

By:

Maione, Federica;
Capano, Stefania;
Regano, Donatella;
Zentilin, Lorena;
Giacca, Mauro;
Casanovas, Oriol;
Bussolino, Federico;
Serini, Guido;
Giraudo, Enrico

Publication type:

Article

A conversation with Robert Lefkowitz, Joseph Goldstein, and Michael Brown. Interview by Ushma S. Neil and Howard A. Rockman.

Published in:

2012

By:

Lefkowitz R;
Goldstein J;
Brown M;
Lefkowitz, Robert;
Goldstein, Joseph;
Brown, Michael

Publication type:

Biography

Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8(+) T cells and activating Foxp3(+) regulatory T cells.

Published in:

2012

By:

Gomez de Agüero M;
Vocanson M;
Hacini-Rachinel F;
Taillardet M;
Sparwasser T;
Kissenpfennig A;
Malissen B;
Kaiserlian D;
Dubois B;
Gomez de Agüero, Mercedes;
Vocanson, Marc;
Hacini-Rachinel, Fériel;
Taillardet, Morgan;
Sparwasser, Tim;
Kissenpfennig, Adrien;
Malissen, Bernard;
Kaiserlian, Dominique;
Dubois, Bertrand

Publication type:

journal article

CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease.

Published in:

2012

By:

De Luca A;
Iannitti RG;
Bozza S;
Beau R;
Casagrande A;
D'Angelo C;
Moretti S;
Cunha C;
Giovannini G;
Massi-Benedetti C;
Carvalho A;
Boon L;
Latgé JP;
Romani L;
De Luca, Antonella;
Iannitti, Rossana G;
Bozza, Silvia;
Beau, Remi;
Casagrande, Andrea;
D'Angelo, Carmen

Publication type:

journal article

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells.

Published in:

2012

By:

Celià-Terrassa T;
Meca-Cortés O;
Mateo F;
de Paz AM;
Rubio N;
Arnal-Estapé A;
Ell BJ;
Bermudo R;
Díaz A;
Guerra-Rebollo M;
Lozano JJ;
Estarás C;
Ulloa C;
Alvarez-Simón D;
Milà J;
Vilella R;
Paciucci R;
Martínez-Balbás M;
de Herreros AG;
Gomis RR

Publication type:

journal article

Anti-ceramide antibody prevents the radiation gastrointestinal syndrome in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1786, doi. 10.1172/JCI59920

By:

Rotolo, Jimmy;
Stancevic, Branka;
Zhang, Jianjun;
Hua, Guoqiang;
Fuller, John;
Yin, Xianglei;
Haimovitz-Friedman, Adriana;
Kim, Kisu;
Qian, Ming;
Cardó-Vila, Marina;
Fuks, Zvi;
Pasqualini, Renata;
Arap, Wadih;
Kolesnick, Richard

Publication type:

Article

Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions.

Published in:

2012

By:

Lin YY;
Hsu YH;
Huang HY;
Shann YJ;
Huang CY;
Wei SC;
Chen CL;
Jou TS;
Lin, Yu-Yu;
Hsu, Yung-Ho;
Huang, Hsin-Yi;
Shann, Yih-Jyh;
Huang, Chi-Ying F;
Wei, Shu-Chen;
Chen, Chi-Ling;
Jou, Tzuu-Shuh

Publication type:

journal article

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice.

Published in:

2012

By:

Quinton LJ;
Blahna MT;
Jones MR;
Allen E;
Ferrari JD;
Hilliard KL;
Zhang X;
Sabharwal V;
Algül H;
Akira S;
Schmid RM;
Pelton SI;
Spira A;
Mizgerd JP;
Quinton, Lee J;
Blahna, Matthew T;
Jones, Matthew R;
Allen, Eri;
Ferrari, Joseph D;
Hilliard, Kristie L

Publication type:

journal article

CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice.

Published in:

2012

By:

Zanoni I;
Ostuni R;
Barresi S;
Di Gioia M;
Broggi A;
Costa B;
Marzi R;
Granucci F;
Zanoni, Ivan;
Ostuni, Renato;
Barresi, Simona;
Di Gioia, Marco;
Broggi, Achille;
Costa, Barbara;
Marzi, Roberta;
Granucci, Francesca

Publication type:

journal article

Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1777, doi. 10.1172/JCI46490

By:

Ying, Wei-Zhong;
Allen, Christopher E.;
Curtis, Lisa M.;
Aaron, Kristal J.;
Sanders, Paul W.

Publication type:

Article

MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1933, doi. 10.1172/JCI40591

By:

Rivas, Magali Noval;
Koh, Yi T.;
Chen, Andrew;
Nguyen, Annie;
Lee, Young Ho;
Lawson, Greg;
Chatila, Talal A.

Publication type:

Article

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1920, doi. 10.1172/JCI57477

By:

Nacerddine, Karim;
Beaudry, Jean-Bernard;
Ginjala, Vasudeva;
Westerman, Bart;
Mattiroli, Francesca;
Song, Ji-Ying;
der Poel, Henk van;
Ponz, Olga Balagué;
Pritchard, Colin;
Cornelissen-Steijger, Paulien;
Zevenhoven, John;
Tanger, Ellen;
Sixma, Titia K.;
Ganesan, Shridar;
Lohuizen, Maarten van

Publication type:

Article

Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1907, doi. 10.1172/JCI58540

By:

Anderson, Philip D.;
McKissic, Sydika A.;
Logan, Monica;
Roh, Meejeon;
Franco, Omar E.;
Wang, Jie;
Doubinskaia, Irina;
der Meer, Riet van;
Hayward, Simon W.;
Eischen, Christine M.;
Eltoum, Isam-Eldin;
Abdulkadir, Sarki A.

Publication type:

Article

SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1895, doi. 10.1172/JCI59858

By:

Chu-An Wang;
Jedlicka, Paul;
Patrick, Aaron N.;
Micalizzi, Douglas S.;
Lemmer, Kimberly C.;
Deitsch, Erin;
Casás-Selves, Matias;
Harrell, J. Chuck;
Ford, Heide L.

Publication type:

Article

Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1881, doi. 10.1172/JCI45661

By:

Yu-Yu Lin;
Yung-Ho Hsu;
Hsin-Yi Huang;
Yih-Jyh Shann;
Chi-Ying F. Huang;
Shu-Chen Wei;
Chi-Ling Chen;
Tzuu-Shuh Jou

Publication type:

Article

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1849

By:

Celià-Terrassa, Toni;
Meca-Cortés, Óscar;
Mateo, Francesca;
de Paz, Alexia Martínez;
Rubio, Nuria;
Arnal-Estapé, Anna;
Ell, Brian J.;
Bermudo, Raquel;
Díaz, Alba;
Guerra-Rebollo, Marta;
Lozano, Juan José;
Estarás, Conchi;
Ulloa, Catalina;
Álvarez-Simón, Daniel;
Milà, Jordi;
Vilella, Ramón;
Paciucci, Rosanna;
Martínez-Balbás, Marian;
de Herreros, Antonio García;
Gomis, Roger R.

Publication type:

Article

ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1869, doi. 10.1172/JCI61492

By:

Long, Weiwen;
Foulds, Charles E.;
Qin, Jun;
Liu, Jian;
Ding, Chen;
Lonard, David M.;
Solis, Luisa M.;
Wistuba, Ignacio I.;
Tsai, Sophia Y.;
Tsai, Ming-Jer;
O'Malley, Bert W.

Publication type:

Article

Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8+ T cells and activating Foxp3+ regulatory T cells.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1700, doi. 10.1172/JCI59725

By:

de Agüero, Mercedes Gomez;
Vocanson, Marc Vocanson;
Hacini-Rachinel, Fériel;
Taillardet, Morgan;
Sparwasser, Tim;
Kissenpfennig, Adrien;
Malissen, Bernard;
Kaiserlian, Dominique;
Dubois, Bertrand

Publication type:

Article

Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1688, doi. 10.1172/JCI59817

By:

Zhang, Yuan;
Breevoort, Sarah R.;
Angdisen, Jerry;
Fu, Mingui;
Schmidt, Daniel R.;
Holmstrom, Sam R.;
Kliewer, Steven A.;
Mangelsdorf, David J.;
Schulman, Ira G.

Publication type:

Article

CD4+ T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1816, doi. 10.1172/JCI60862

By:

De Luca, Antonella;
Iannitti, Rossana G.;
Bozza, Silvia;
Beau, Remi;
Casagrande, Andrea;
D'Angelo, Carmen;
Moretti, Silvia;
Cunha, Cristina;
Giovannini, Gloria;
Massi-Benedetti, Cristina;
Carvalho, Agostinho;
Boon, Louis;
Latgé, Jean-Paul;
Romani, Luigina

Publication type:

Article

Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1803, doi. 10.1172/JCI45890

By:

Lieben, Liesbet;
Masuyama, Ritsuko;
Torrekens, Sophie;
Looveren, Riet Van;
Schrooten, Jan;
Baatsen, Pieter;
Lafage-Proust, Marie-Hélène;
Dresselaers, Tom;
Feng, Jian Q.;
Bonewald, Lynda F.;
Meyer, Mark B.;
Pike, J. Wesley;
Bouillon, Roger;
Carmeliet, Geert

Publication type:

Article

Hepatocyte-specific mutation of both NF-κB RelA and STAT3 abrogates the acute phase response in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1758, doi. 10.1172/JCI59408

By:

Quinton, Lee J.;
Blahna, Matthew T.;
Jones, Matthew R.;
Allen, Eri;
Ferrari, Joseph D.;
Hilliard, Kristie L.;
Zhang, Xiaoling;
Sabharwal, Vishakha;
Algül, Hana;
Akira, Shizuo;
Schmid, Roland M.;
Pelton, Stephen I.;
Spira, Avrum;
Mizgerd, Joseph P.

Publication type:

Article

Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1764, doi. 10.1172/JCI59581

By:

Kudryashova, Elena;
Kramerova, Irina;
Spencer, Melissa J.

Publication type:

Article

Gene therapy: too much splice can spoil the dish.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1600, doi. 10.1172/JCI63066

By:

Trono, Didier

Publication type:

Article

Whole transcriptome characterization of aberrant splicing events induced by lentiviral vector integrations.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1667, doi. 10.1172/JCI62189

By:

Cesana, Daniela;
Sgualdino, Jacopo;
Rudilosso, Laura;
Merella, Stefania;
Naldini, Luigi;
Montini, Eugenio

Publication type:

Article

Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1734, doi. 10.1172/JCI62385

By:

Ray, Partha;
Rialon-Guevara, Kristy L.;
Veras, Emanuela;
Sullenger, Bruce A.;
White, Rebekah R.

Publication type:

Article

CD14 and NFAT mediate lipopolysaccharideinduced skin edema formation in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1747, doi. 10.1172/JCI60688

By:

Zanoni, Ivan;
Ostuni, Renato;
Barresi, Simona;
Gioia, Marco Di;
Broggi, Achille;
Costa, Barbara;
Marzi, Roberta;
Granucci, Francesca

Publication type:

Article

Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1742, doi. 10.1172/JCI61976

By:

Kiritsi, Dimitra;
He, Yinghong;
Pasmooij, Anna M. G.;
Onder, Meltem;
Happle, Rudolf;
Jonkman, Marcel F.;
Bruckner-Tuderman, Leena;
Has, Cristina

Publication type:

Article

Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1717, doi. 10.1172/JCI60530

By:

Takiishi, Tatiana;
Korf, Hannelie;
Van Belle, Tom L.;
Robert, Sofie;
Grieco, Fabio A.;
Caluwaerts, Silvia;
Galleri, Letizia;
Spagnuolo, Isabella;
Steidler, Lothar;
Huynegem, Karolien Van;
Demetter, Pieter;
Wasserfall, Clive;
Atkinson, Mark A.;
Dotta, Francesco;
Rottiers, Pieter;
Gysemans, Conny;
Mathieu, Chantal

Publication type:

Article

Cooperation between Rb and Arf in suppressing mouse retinoblastoma.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1726, doi. 10.1172/JCI61403

By:

Conkrite, Karina;
Sundby, Maggie;
Mu, David;
Mukai, Shizuo;
MacPherson, David

Publication type:

Article

PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1712, doi. 10.1172/JCI60612

By:

Shetty, Ravi Dyavar;
Velu, Vijayakumar;
Titanji, Kehmia;
Bosinger, Steven E.;
Freeman, Gordon J.;
Silvestri, Guido;
Amara, Rama Rao

Publication type:

Article

Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1653, doi. 10.1172/JCI61852

By:

Moiani, Arianna;
Paleari, Ylenia;
Sartori, Daniela;
Mezzadra, Riccardo;
Miccio, Annarita;
Cattoglio, Claudia;
Cocchiarella, Fabienne;
Lidonnici, Maria Rosa;
Ferrari, Giuliana;
Mavilio, Fulvio

Publication type:

Article

Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1644, doi. 10.1172/JCI61429

By:

Bibollet-Ruche, Frederic;
Heigele, Anke;
Keele, Brandon F.;
Easlick, Juliet L.;
Decker, Julie M.;
Takehisa, Jun;
Learn, Gerald;
Sharp, Paul M.;
Hahn, Beatrice H.;
Kirchhoff, Frank

Publication type:

Article

Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1677, doi. 10.1172/JCI61248

By:

Ai, Ding;
Baez, Juan M.;
Jiang, Hongfeng;
Conlon, Donna M.;
Hernandez-Ono, Antonio;
Frank-Kamenetsky, Maria;
Milstein, Stuart;
Fitzgerald, Kevin;
Murphy, Andrew J.;
Woo, Connie W.;
Strong, Alanna;
Ginsberg, Henry N.;
Tabas, Ira;
Rader, Daniel J.;
Tall, Alan R.

Publication type:

Article

The DC receptor DNGR-1 mediates cross-priming of CTLs during vaccinia virus infection in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1628, doi. 10.1172/JCI60660

By:

Iborra, Salvador;
Izquierdo, Helena M.;
Martínez-López, María;
Blanco-Menéndez, Noelia;
Sousa, Caetano Reis E.;
Sancho, David

Publication type:

Article

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1615, doi. 10.1172/JCI60644

By:

Zelenay, Santiago;
Keller, Anna M.;
Whitney, Paul G.;
Schraml, Barbara U.;
Deddouche, Safia;
Rogers, Neil C.;
Schulz, Oliver;
Sancho, David;
e Sousa, Caetano Reis

Publication type:

Article

NADPH oxidase regulates efficacy of vaccination in aspergillosis.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1608, doi. 10.1172/JCI63417

By:

Deepe, George S.

Publication type:

Article

How much vitamin D should I take?

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1598, doi. 10.1172/JCI62966

By:

Colón-Emeric, Cathleen S.;
Lyles, Kenneth W.

Publication type:

Article

Lloyd J. Old -- a scientific concertmaster.

Published in:

2012

By:

Puré, Ellen

Publication type:

Obituary

Enhancing immune responses to limit chronic immune activation during SIV.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1611, doi. 10.1172/JCI63389

By:

Estes, Jacob D.

Publication type:

Article

Treating myeloma cast nephropathy without treating myeloma.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1605, doi. 10.1172/JCI63248

By:

Leung, Nelson

Publication type:

Article

Constitutively, pathologically, profoundly.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1585, doi. 10.1172/JCI64042

By:

Neill, Ushma S.

Publication type:

Article

Epidermal Langerhans cells tune skin reactivity to contact allergens.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1602, doi. 10.1172/JCI63190

By:

Udey, Mark C.

Publication type:

Article

A conversation with Robert Lefkowitz, Joseph Goldstein, and Michael Brown.

Published in:

2012

By:

Neill, Ushma S.;
Rockman, Howard A.

Publication type:

Interview

Degranulation deconstructed.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1596, doi. 10.1172/JCI62990

By:

Baehner, Robert L.;
Karnovsky, Morris J.

Publication type:

Article

Uncovering the role of genomic "dark matter" in human disease.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 5, p. 1589, doi. 10.1172/JCI60020

By:

Martin, Lance;
Chang, Howard Y.

Publication type:

Article