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A Randomized Trial of the N-Methyl-d-Aspartate Receptor Glycine Site Antagonist Prodrug 4-Chlorokynurenine in Treatment-Resistant Depression.
Published in:
International Journal of Neuropsychopharmacology, 2020, v. 23, n. 7, p. 417, doi. 10.1093/ijnp/pyaa025
By:
- Park, Lawrence T;
- Kadriu, Bashkim;
- Gould, Todd D;
- Zanos, Panos;
- Greenstein, Deanna;
- Evans, Jennifer W;
- Yuan, Peixiong;
- Farmer, Cristan A;
- Oppenheimer, Mark;
- George, Jomy M;
- Adeojo, Lilian W;
- Snodgrass, H Ralph;
- Smith, Mark A;
- Henter, Ioline D;
- Machado-Vieira, Rodrigo;
- Mannes, Andrew J;
- Zarate, Carlos A
Publication type:
Article
Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08100-8
By:
- Hall, Bradford E.;
- Macdonald, Emma;
- Cassidy, Margaret;
- Yun, Sijung;
- Sapio, Matthew R.;
- Ray, Pradipta;
- Doty, Megan;
- Nara, Pranavi;
- Burton, Michael D.;
- Shiers, Stephanie;
- Ray-Chaudhury, Abhik;
- Mannes, Andrew J.;
- Price, Theodore J.;
- Iadarola, Michael J.;
- Kulkarni, Ashok B.
Publication type:
Article
Deletion of vanilloid receptor 1--expressing primary afferent neurons for pain control.
Published in:
Journal of Clinical Investigation, 2004, v. 113, n. 9, p. 1344, doi. 10.1172/JCI200420449
By:
- Karai, Laszlo;
- Brown, Dorothy C.;
- Mannes, Andrew J.;
- Connelly, Stephen T.;
- Brown, Jacob;
- Gandal, Michael;
- Wellisch, Ofer M.;
- Neubert, John K.;
- Olah, Zoltan;
- Iadarola, Michael J.
Publication type:
Article
RNA-Seq investigations of human post-mortem trigeminal ganglia.
Published in:
Cephalalgia, 2018, v. 38, n. 5, p. 912, doi. 10.1177/0333102417720216
By:
- LaPaglia, Danielle M.;
- Sapio, Matthew R.;
- Burbelo, Peter D.;
- Thierry-Mieg, Jean;
- Thierry-Mieg, Danielle;
- Raithel, Stephen J.;
- Ramsden, Christopher E.;
- Iadarola, Michael J.;
- Mannes, Andrew J.
Publication type:
Article
RNA-Seq investigations of human post-mortem trigeminal ganglia.
Published in:
2018
By:
- LaPaglia, Danielle M;
- Sapio, Matthew R;
- Burbelo, Peter D;
- Thierry-Mieg, Jean;
- Thierry-Mieg, Danielle;
- Raithel, Stephen J;
- Ramsden, Christopher E;
- Iadarola, Michael J;
- Mannes, Andrew J
Publication type:
journal article
A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch.
Published in:
Science Signaling, 2017, v. 10, n. 493, p. 1, doi. 10.1126/scisignal.aal5241
By:
- Zhi-Xin Yuan;
- Keyes, Gregory S.;
- Horowitz, Mark S.;
- Ramsden, Christopher E.;
- Domenichiello, Anthony F.;
- Zamora, Daisy;
- Davis, John M.;
- Vasko, Michael R.;
- Majchrzak-Hong, Sharon;
- Sapio, Matthew R.;
- Gross, Jacklyn R.;
- LaPaglia, Danielle M.;
- Mannes, Andrew J.;
- Iadarola, Michael J.;
- Mishra, Santosh K.;
- Wheeler, Joshua J.;
- Sorokin, Alexander.V.;
- Dey, Amit;
- Mehta, Nehal N.
Publication type:
Article
Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.705743
By:
- Iadarola, Michael J.;
- Brown, Dorothy Cimino;
- Nahama, Alexis;
- Sapio, Matthew R.;
- Mannes, Andrew J.
Publication type:
Article
Comparative Analysis of Dorsal Root, Nodose and Sympathetic Ganglia for the Development of New Analgesics.
Published in:
Frontiers in Neuroscience, 2020, v. 11, p. N.PAG, doi. 10.3389/fnins.2020.615362
By:
- Sapio, Matthew R.;
- Vazquez, Fernando A.;
- Loydpierson, Amelia J.;
- Maric, Dragan;
- Kim, Jenny J.;
- LaPaglia, Danielle M.;
- Puhl, Henry L.;
- Lu, Van B.;
- Ikeda, Stephen R.;
- Mannes, Andrew J.;
- Iadarola, Michael J.
Publication type:
Article
Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin.
Published in:
BMC Neuroscience, 2007, v. 8, p. 30, doi. 10.1186/1471-2202-8-30
By:
- Caudle, Robert M.;
- Mannes, Andrew J.;
- Keller, Jason;
- Perez, Federico M.;
- Suckow, Shelby K.;
- Neubert, John K.
Publication type:
Article
Anatomical Analysis of Transient Potential Vanilloid Receptor 1 (Trpv1+) and Mu-Opioid Receptor (Oprm1+) Co-expression in Rat Dorsal Root Ganglion Neurons.
Published in:
Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.926596
By:
- Ma, Wenting;
- Sapio, Matthew R.;
- Manalo, Allison P.;
- Maric, Dragan;
- Dougherty, Mary Kate;
- Goto, Taichi;
- Mannes, Andrew J.;
- Iadarola, Michael J.
Publication type:
Article
Transcriptional Activation, Deactivation and Rebound Patterns in Cortex, Hippocampus and Amygdala in Response to Ketamine Infusion in Rats.
Published in:
Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.892345
By:
- Kim, Jenny J.;
- Sapio, Matthew R.;
- Vazquez, Fernando A.;
- Maric, Dragan;
- Loydpierson, Amelia J.;
- Ma, Wenting;
- Zarate Jr., Carlos A.;
- Iadarola, Michael J.;
- Mannes, Andrew J.
Publication type:
Article
Longitudinal peripheral tissue RNA-Seq transcriptomic profiling, hyperalgesia, and wound healing in the rat plantar surgical incision model.
Published in:
FASEB Journal, 2021, v. 35, n. 10, p. 1, doi. 10.1096/fj.202100347R
By:
- Taichi Goto;
- Sapio, Matthew R.;
- Maric, Dragan;
- Robinson, Jeffrey M.;
- Domenichiello, Anthony F.;
- Saligan, Leorey N.;
- Mannes, Andrew J.;
- Iadarola, Michael J.
Publication type:
Article
Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons.
Published in:
2018
By:
- Sapio, Matthew R.;
- Neubert, John K.;
- LaPaglia, Danielle M.;
- Maric, Dragan;
- Keller, Jason M.;
- Raithel, Stephen J.;
- Rohrs, Eric L.;
- Anderson, Ethan M.;
- Butman, John A.;
- Caudle, Robert M.;
- Brown, Dorothy C.;
- Heiss, John D.;
- Mannes, Andrew J.;
- Iadarola, Michael J.
Publication type:
journal article
A new splice of life for the μ-opioid receptor.
Published in:
2015
By:
- Iadarola, Michael J.;
- Sapio, Matthew R.;
- Mannes, Andrew J.
Publication type:
Opinion
Analgesia by deletion of spinal neurokinin 1 receptor expressing neurons using a bioengineered substance P-Pseudomonas exotoxin conjugate.
Published in:
Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917727657
By:
- Iadarola, Michael J.;
- Sapio, Matthew R.;
- Wang, Xunde;
- Carrero, Hector;
- Virata-Theimer, Maria Luisa;
- Sarnovsky, Robert;
- Mannes, Andrew J.;
- FitzGeralD, David J.
Publication type:
Article
Analgesia by Deletion of Spinal Neurokinin 1 Receptor Expressing Neurons Using a Bioengineered Substance P-Pseudomonas Exotoxin Conjugate.
Published in:
Molecular Pain, 2017, v. 13, p. 43, doi. 10.1177/1744806917727657
By:
- Iadarola, Michael J.;
- Sapio, Matthew R.;
- Xunde Wang;
- Carrero, Hector;
- Virata-Theimer, Maria Luisa;
- Sarnovsky, Robert;
- Mannes, Andrew J.;
- FitzGerald, David J.
Publication type:
Article
Analgesia by deletion of spinal neurokinin 1 receptor expressing neurons using a bioengineered substance P-Pseudomonas exotoxin conjugate.
Published in:
Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917727657
By:
- Iadarola, Michael J.;
- Sapio, Matthew R.;
- Xunde Wang;
- Carrero, Hector;
- Virata-Theimer, Maria Luisa;
- Sarnovsky, Robert;
- Mannes, Andrew J.;
- FitzGerald, David J.
Publication type:
Article
Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord.
Published in:
Molecular Pain, 2014, v. 10, n. 1, p. 1, doi. 10.1186/1744-8069-10-44
By:
- Goswami, Samridhi C.;
- Thierry-Mieg, Danielle;
- Thierry-Mieg, Jean;
- Mishra, Santosh;
- Hoon, Mark A.;
- Mannes, Andrew J.;
- Iadarola, Michael J.
Publication type:
Article
Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia.
Published in:
Molecular Pain, 2008, v. 4, n. 1, p. 1, doi. 10.1186/1744-8069-4-3
By:
- Neubert, John K.;
- Mannes, Andrew J.;
- Karai, Laszlo J.;
- Jenkins, Alan C.;
- Zawatski, Lanel;
- Abu-Asab, Mones;
- Iadarola, Michael J.
Publication type:
Article
Anti-cytokine autoantibodies in postherpetic neuralgia.
Published in:
2015
By:
- Bayat, Ahmad;
- Burbelo, Peter D.;
- Browne, Sarah K.;
- Quinlivan, Mark;
- Martinez, Bianca;
- Holland, Steven M.;
- Buvanendran, Asokumar;
- Kroin, Jeffrey S.;
- Mannes, Andrew J.;
- Breuer, Judith;
- Cohen, Jeffrey I.;
- Iadarola, Michael J
Publication type:
journal article
Lipidomic profiling of targeted oxylipins with ultra-performance liquid chromatography-tandem mass spectrometry.
Published in:
Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 23, p. 6009, doi. 10.1007/s00216-018-1222-4
By:
- Yuan, Zhi-Xin;
- Majchrzak-Hong, Sharon;
- Keyes, Gregory S.;
- Iadarola, Michael J.;
- Mannes, Andrew J.;
- Ramsden, Christopher E.
Publication type:
Article
In-line miniature 3D-printed pressure-cycled ventilator maintains respiratory homeostasis in swine with induced acute pulmonary injury.
Published in:
Science Translational Medicine, 2022, v. 14, n. 666, p. 1, doi. 10.1126/scitranslmed.abm8351
By:
- Pritchard, William F.;
- Karanian, John W.;
- Jung, Chris;
- Bakhutashvili, Ivane;
- Reed, Sheridan L.;
- Starost, Matthew F.;
- Froelke, Brian R.;
- Barnes, Teresa R.;
- Stevenson, Duncan;
- Mendoza, Artemio;
- Eckstein, David J.;
- Wood, Bradford J.;
- Walsh, Brian K.;
- Mannes, Andrew J.
Publication type:
Article
Oral Ketamine in the Palliative Care Setting: A Review of the Literature and Case Report of a Patient With Neurofibromatosis Type 1 and Glomus Tumor-Associated Complex Regional Pain Syndrome.
Published in:
2012
By:
- Soto, Eliezer;
- Stewart, Douglas R.;
- Mannes, Andrew J.;
- Ruppert, Sarah L.;
- Baker, Karen;
- Zlott, Daniel;
- Handel, Daniel;
- Berger, Ann M.
Publication type:
Journal Article

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