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Sialic acid is a critical fetal defense against maternal complement attack.
Published in:
2019
By:
- Abeln, Markus;
- Albers, Iris;
- Peters-Bernard, Ulrike;
- Flächsig-Schulz, Kerstin;
- Kats, Elina;
- Kispert, Andreas;
- Tomlinson, Stephen;
- Gerardy-Schahn, Rita;
- Münster-Kühnel, Anja;
- Weinhold, Birgit
Publication type:
journal article
Brown adipose tissue-specific insulin receptor knockout shows diabetic phenotype without insulin resistance.
Published in:
2019
By:
- Guerra, Carmen;
- Navarro, Paloma;
- Valverde, Angela M.;
- Arribas, Monica;
- Brüning, Jens;
- Kozak, Leslie P.;
- Kahn, C. Ronald;
- Benito, Manuel
Publication type:
journal article
Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis.
Published in:
2019
By:
- Pickering, Raelene J.;
- Tikellis, Christos;
- Rosado, Carlos J.;
- Tsorotes, Despina;
- Dimitropoulos, Alexandra;
- Smith, Monique;
- Huet, Olivier;
- Seeber, Ruth M.;
- Abhayawardana, Rekhati;
- Johnstone, Elizabeth K. M.;
- Golledge, Jonathan;
- Yutang Wang;
- Jandeleit-Dahm, Karin A.;
- Cooper, Mark E.;
- Pfleger, Kevin D. G.;
- Thomas, Merlin C.;
- Johnstone, Elizabeth Km;
- Wang, Yutang;
- Pfleger, Kevin Dg
Publication type:
journal article
Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema.
Published in:
2019
By:
- Haslund, Didde;
- Ryø, Laura Barrett;
- Majidi, Sara Seidelin;
- Rose, Iben;
- Skipper, Kristian Alsbjerg;
- Fryland, Tue;
- Bohn, Anja Bille;
- Koch, Claus;
- Thomsen, Martin K.;
- Palarasah, Yaseelan;
- Corydon, Thomas J.;
- Bygum, Anette;
- Nejsum, Lene N.;
- Mikkelsen, Jacob Giehm;
- Seidelin Majidi, Sara;
- Rose, Iben Kløvgaard
Publication type:
journal article
PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia.
Published in:
2019
By:
- Gilbert, Tonya M.;
- Zürcher, Nicole R.;
- Wu, Christine J.;
- Bhanot, Anisha;
- Hightower, Baileigh G.;
- Kim, Minhae;
- Albrecht, Daniel S.;
- Hsiao-Ying Wey;
- Schroeder, Frederick A.;
- Rodriguez-Thompson, Anais;
- Morin, Thomas M.;
- Hart, Kamber L.;
- Pellegrini, Amelia M.;
- Riley, Misha M.;
- Changning Wang;
- Stufflebeam, Steven M.;
- Haggarty, Stephen J.;
- Holt, Daphne J.;
- Loggia, Marco L.;
- Perlis, Roy H.
Publication type:
journal article
Bacterial sepsis triggers an antiviral response that causes translation shutdown.
Published in:
2019
By:
- Takashi Hato;
- Maier, Bernhard;
- Syed, Farooq;
- Myslinski, Jered;
- Zollman, Amy;
- Plotkin, Zoya;
- Eadon, Michael T.;
- Dagher, Pierre C.;
- Hato, Takashi
Publication type:
journal article
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
Published in:
2019
By:
- Koeth, Robert A.;
- Lam-Galvez, Betzabe Rachel;
- Kirsop, Jennifer;
- Zeneng Wang;
- Levison, Bruce S.;
- Xiaodong Gu;
- Copeland, Matthew F.;
- Bartlett, David;
- Cody, David B.;
- Dai, Hong J.;
- Culley, Miranda K.;
- Li, Xinmin S.;
- Xiaoming Fu;
- Yuping Wu;
- Lin Li;
- DiDonato, Joseph A.;
- Tang, W. H. Wilson;
- Garcia-Garcia, Jose Carlos;
- Hazen, Stanley L.;
- Wang, Zeneng
Publication type:
journal article
Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.
Published in:
2019
By:
- Chien-Chun Steven Pai;
- Simons, Donald M.;
- Xiaoqing Lu;
- Evans, Michael;
- Junnian Wei;
- Yung-hua Wang;
- Mingyi Chen;
- Huang, John;
- Chanhyuk Park;
- Chang, Anthony;
- Jiaxi Wang;
- Westmoreland, Susan;
- Beam, Christine;
- Banach, Dave;
- Bowley, Diana;
- Feng Dong;
- Seaga, Jane;
- Ritacco, Wendy;
- Richardson, Paul L.;
- Mitra, Soumya
Publication type:
journal article
Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload.
Published in:
2019
By:
- Schwartz, Andrew J.;
- Das, Nupur K.;
- Ramakrishnan, Sadeesh K.;
- Jain, Chesta;
- Jurkovic, Mladen T.;
- Jun Wu;
- Nemeth, Elizabeta;
- Lakhal-Littleton, Samira;
- Colacino, Justin A.;
- Shah, Yatrik M.;
- Jurkovic, Mladen;
- Wu, Jun
Publication type:
journal article
Human islets expressing HNF1A variant have defective β cell transcriptional regulatory networks.
Published in:
2019
By:
- Haliyur, Rachana;
- Xin Tong;
- May Sanyoura;
- Shrestha, Shristi;
- Lindner, Jill;
- Saunders, Diane C.;
- Aramandla, Radhika;
- Poffenberger, Greg;
- Redick, Sambra D.;
- Bottino, Rita;
- Prasad, Nripesh;
- Levy, Shawn E.;
- Blind, Raymond D.;
- Harlan, David M.;
- Philipson, Louis H.;
- Stein, Roland W.;
- Brissova, Marcela;
- Powers, Alvin C.;
- Tong, Xin;
- Sanyoura, May
Publication type:
journal article
Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis.
Published in:
2019
By:
- Peixiang Zhang;
- Csaki, Lauren S.;
- Ronquillo, Emilio;
- Baufeld, Lynn J.;
- Lin, Jason Y.;
- Gutierrez, Alexis;
- Dwyer, Jennifer R.;
- Brindley, David N.;
- Fong, Loren G.;
- Tontonoz, Peter;
- Young, Stephen G.;
- Reue, Karen;
- Zhang, Peixiang
Publication type:
journal article
Notch signaling dynamically regulates adult β cell proliferation and maturity.
Published in:
2019
By:
- Bartolome, Alberto;
- Changyu Zhu;
- Sussel, Lori;
- Pajvani, Utpal B.;
- Zhu, Changyu
Publication type:
journal article
Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression.
Published in:
2019
By:
- Poncette, Lucia;
- Xiaojing Chen;
- Lorenz, Felix K. M.;
- Blankenstein, Thomas;
- Chen, Xiaojing;
- Lorenz, Felix Km
Publication type:
journal article
Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits.
Published in:
2019
By:
- Qi-Gang Zhou;
- Nemes, Ashley D.;
- Daehoon Lee;
- Eun Jeoung Ro;
- Jing Zhang;
- Nowacki, Amy S.;
- Dymecki, Susan M.;
- Najm, Imad M.;
- Hoonkyo Suh;
- Zhou, Qi-Gang;
- Lee, Daehoon;
- Ro, Eun Jeoung;
- Zhang, Jing;
- Suh, Hoonkyo
Publication type:
journal article
An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.
Published in:
Journal of Clinical Investigation, 2019, v. 129, n. 1, p. 169, doi. 10.1172/JCI121087
By:
- Christenson, Stephanie A.;
- van den Berge, Maarten;
- Faiz, Alen;
- Inkamp, Kai;
- Bhakta, Nirav;
- Bonser, Luke R.;
- Zlock, Lorna T.;
- Barjaktarevic, Igor Z.;
- Barr, R. Graham;
- Bleecker, Eugene R.;
- Boucher, Richard C.;
- Bowler, Russell P.;
- Comellas, Alejandro P.;
- Curtis, Jeffrey L.;
- Han, MeiLan K.;
- Hansel, Nadia N.;
- Hiemstra, Pieter S.;
- Kaner, Robert J.;
- Krishnanm, Jerry A.;
- Martinez, Fernando J.
Publication type:
Article
DNA hypermethylation within TERT promoter upregulates TERT expression in cancer.
Published in:
2019
By:
- Lee, Donghyun D.;
- Leão, Ricardo;
- Komosa, Martin;
- Gallo, Marco;
- Zhang, Cindy H.;
- Lipman, Tatiana;
- Remke, Marc;
- Heidari, Abolfazl;
- Nunes, Nuno Miguel;
- Apolónio, Joana D.;
- Price, Aryeh J.;
- De Mello, Ramon Andrade;
- Dias, João S.;
- Huntsman, David;
- Hermanns, Thomas;
- Wild, Peter J.;
- Vanner, Robert;
- Zadeh, Gelareh;
- Karamchandani, Jason;
- Das, Sunit
Publication type:
journal article
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Published in:
2019
By:
- Shanshan Zhong;
- Luxiao Li;
- Yu-Lei Zhang;
- Lili Zhang;
- Jianhong Lu;
- Shuyuan Guo;
- Ningning Liang;
- Jing Ge;
- Mingjiang Zhu;
- Yongzhen Tao;
- Yun-Cheng Wu;
- Huiyong Yin;
- Zhong, Shanshan;
- Li, Luxiao;
- Zhang, Yu-Lei;
- Zhang, Lili;
- Lu, Jianhong;
- Guo, Shuyuan;
- Liang, Ningning;
- Ge, Jing
Publication type:
journal article
TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy.
Published in:
2019
By:
- Sharma, Deepika;
- Malik, Ankit;
- Guy, Clifford;
- Vogel, Peter;
- Kanneganti, Thirumala-Devi
Publication type:
journal article
Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis.
Published in:
2019
By:
- Ming Chen;
- Jiangwen Zhang;
- Berger, Alice H.;
- Diolombi, Moussa S.;
- Ng, Christopher;
- Fung, Jacqueline;
- Bronson, Roderick T.;
- Castillo-Martin, Mireia;
- Tin Htwe Thin;
- Cordon-Cardo, Carlos;
- Plevin, Robin;
- Pandolfi, Pier Paolo;
- Chen, Ming;
- Zhang, Jiangwen;
- Thin, Tin Htwe
Publication type:
journal article
Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain.
Published in:
2019
By:
- Sungro Jo;
- Fonseca, Tatiana L.;
- Bocco, Barbara M. L. C.;
- Fernandes, Gustavo W.;
- McAninch, Elizabeth A.;
- Bolin, Anaysa P.;
- Da Conceição, Rodrigo R.;
- Werneck-de-Castro, Joao Pedro;
- Ignacio, Daniele L.;
- Egri, Péter;
- Németh, Dorottya;
- Fekete, Csaba;
- Bernardi, Maria Martha;
- Leitch, Victoria D.;
- Mannan, Naila S.;
- Curry, Katharine F.;
- Butterfield, Natalie C.;
- Bassett, J. H. Duncan;
- Williams, Graham R.;
- Gereben, Balázs
Publication type:
journal article
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer.
Published in:
2019
By:
- Sharp, Adam;
- Coleman, Ilsa;
- Wei Yuan;
- Sprenger, Cynthia;
- Dolling, David;
- Rodrigues, Daniel Nava;
- Russo, Joshua W.;
- Figueiredo, Ines;
- Bertan, Claudia;
- Seed, George;
- Riisnaes, Ruth;
- Takuma Uo;
- Neeb, Antje;
- Welti, Jonathan;
- Morrissey, Colm;
- Carreira, Suzanne;
- Jun Luo;
- Nelson, Peter S.;
- Balk, Steven P.;
- True, Lawrence D.
Publication type:
journal article
Spec-seq unveils transcriptional subpopulations of antibody-secreting cells following influenza vaccination.
Published in:
2019
By:
- Neu, Karlynn E.;
- Guthmiller, Jenna J.;
- Min Huang;
- Jennifer La;
- Vieira, Marcos C.;
- Kangchon Kim;
- Nai-Ying Zheng;
- Cortese, Mario;
- Tepora, Micah E.;
- Hamel, Natalie J.;
- Rojas, Karla Thatcher;
- Henry, Carole;
- Shaw, Dustin;
- Dulberger, Charles L.;
- Pulendran, Bali;
- Cobey, Sarah;
- Khan, Aly A.;
- Wilson, Patrick C.;
- Huang, Min;
- La, Jennifer
Publication type:
journal article
Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication.
Published in:
2019
By:
- Ou, Kristy;
- Ming Yu;
- Moss, Nicholas G.;
- Wang, Yue J.;
- Wang, Amber W.;
- Nguyen, Son C.;
- Jiang, Connie;
- Feleke, Eseye;
- Kameswaran, Vasumathi;
- Joyce, Eric F.;
- Naji, Ali;
- Glaser, Benjamin;
- Avrahami, Dana;
- Kaestner, Klaus H.;
- Yu, Ming
Publication type:
journal article
CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome.
Published in:
2019
By:
- Motoko Unoki;
- Hironori Funabiki;
- Velasco, Guillaume;
- Francastel, Claire;
- Sasaki, Hiroyuki;
- Unoki, Motoko;
- Funabiki, Hironori
Publication type:
journal article
Fc-dependent functions are redundant to efficacy of anti-HIV antibody PGT121 in macaques.
Published in:
2019
By:
- Parsons, Matthew S.;
- Wen Shi Lee;
- Kristensen, Anne B.;
- Amarasena, Thakshila;
- Khoury, Georges;
- Wheatley, Adam K.;
- Reynaldi, Arnold;
- Wines, Bruce D.;
- Hogarth, P. Mark;
- Davenport, Miles P.;
- Kent, Stephen J.;
- Lee, Wen Shi
Publication type:
journal article
An adapted anti-CTLA4 therapeutic aimed at mitigating the toxicities of checkpoint inhibition.
Published in:
2019
By:
- Naidoo, Jarushka;
- Dykema, Arbor;
- D'Alessio, Franco
Publication type:
journal article
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target.
Published in:
2019
By:
- Jun Wei;
- Marisetty, Anantha;
- Schrand, Brett;
- Gabrusiewicz, Konrad;
- Yuuri Hashimoto;
- Ott, Martina;
- Grami, Zacharia;
- Ling-Yuan Kong;
- Xiaoyang Ling;
- Caruso, Hillary;
- Shouhao Zhou;
- Wang, Y. Alan;
- Fuller, Gregory N.;
- Huse, Jason;
- Gilboa, Eli;
- Nannan Kang;
- Xingxu Huang;
- Verhaak, Roel;
- Shulin Li;
- Heimberger, Amy B.
Publication type:
journal article
Ube3a reinstatement mitigates epileptogenesis in Angelman syndrome model mice.
Published in:
2019
By:
- Bin Gu;
- Carstens, Kelly E.;
- Judson, Matthew C.;
- Dalton, Katherine A.;
- Rougié, Marie;
- Clark, Ellen P.;
- Dudek, Serena M.;
- Philpot, Benjamin D.;
- Gu, Bin
Publication type:
journal article
At the crossroads of oxygen and iron sensing: hepcidin control of HIF-2α.
Published in:
2019
By:
- Lee, Frank S.
Publication type:
journal article
PI3K p110δ inactivation antagonizes chronic lymphocytic leukemia and reverses T cell immune suppression.
Published in:
2019
By:
- Shuai Dong;
- Harrington, Bonnie K.;
- Hu, Eileen Y.;
- Greene, Joseph T.;
- Lehman, Amy M.;
- Minh Tran;
- Wasmuth, Ronni L.;
- Meixiao Long;
- Muthusamy, Natarajan;
- Brown, Jennifer R.;
- Johnson, Amy J.;
- Byrd, John C.;
- Dong, Shuai;
- Tran, Minh;
- Long, Meixiao
Publication type:
journal article
Bone marrow transplantation generates T cell-dependent control of myeloma in mice.
Published in:
2019
By:
- Vuckovic, Slavica;
- Minnie, Simone A.;
- Smith, David;
- Gartlan, Kate H.;
- Watkins, Thomas S.;
- Markey, Kate A.;
- Mukhopadhyay, Pamela;
- Guillerey, Camille;
- Kuns, Rachel D.;
- Locke, Kelly R.;
- Pritchard, Antonia L.;
- Johansson, Peter A.;
- Varelias, Antiopi;
- Ping Zhang;
- Huntington, Nicholas D.;
- Waddell, Nicola;
- Chesi, Marta;
- Miles, John J.;
- Smyth, Mark J.;
- Hill, Geoffrey R.
Publication type:
journal article
High-affinity T cell receptors for adoptive cell transfer.
Published in:
2019
By:
- Isser, Ariel;
- Schneck, Jonathan P.
Publication type:
journal article
The hereditary angioedema syndromes.
Published in:
2019
By:
- Schmaier, Alvin H.
Publication type:
journal article
Not just correlative: a new pathway defines how an ALDH2 SNP contributes to atherosclerosis.
Published in:
2019
By:
- Gibb, Andrew A.;
- Elrod, John W.
Publication type:
journal article
Targeting protein translation to prevent septic kidney injury.
Published in:
2019
By:
- Huen, Sarah C.
Publication type:
journal article
To absorb fat - supersize my lipid droplets.
Published in:
2019
By:
- Goldberg, Ira J.;
- Hussain, M. Mahmood
Publication type:
journal article
Cognitive function in hypothyroidism: what is that deiodinase again?
Published in:
2019
By:
- Hernandez, Arturo
Publication type:
journal article
Blocking HIV-1 replication: are Fc-Fcγ receptor interactions required?
Published in:
2019
By:
- Forthal, Donald;
- Finzi, Andrés
Publication type:
journal article
Rejuvenation of β cells by epigenetic editing.
Published in:
2019
By:
- Tao Wang;
- Duanqing Pei;
- Wang, Tao;
- Pei, Duanqing
Publication type:
journal article
Mixing old and young: enhancing rejuvenation and accelerating aging.
Published in:
2019
By:
- Lau, Ashley;
- Kennedy, Brian K.;
- Kirkland, James L.;
- Tullius, Stefan G.
Publication type:
journal article
Immunotherapy transforms cancer treatment.
Published in:
2019
By:
- Zaidi, Neeha;
- Jaffee, Elizabeth M.
Publication type:
journal article
Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas.
Published in:
2019
By:
- Area-Gomez, Estela;
- Guardia-Laguarta, Cristina;
- Schon, Eric A.;
- Przedborski, Serge
Publication type:
journal article
Molecular imaging of fibrosis: recent advances and future directions.
Published in:
2019
By:
- Montesi, Sydney B.;
- Désogère, Pauline;
- Fuchs, Bryan C.;
- Caravan, Peter
Publication type:
journal article
Functional significance of the platelet immune receptors GPVI and CLEC-2.
Published in:
2019
By:
- Rayes, Julie;
- Watson, Steve P.;
- Nieswandt, Bernhard
Publication type:
journal article
Autologous graft versus myeloma: it's not a myth.
Published in:
2019
By:
- Shuai Dong;
- Ghobrial, Irene M.;
- Dong, Shuai
Publication type:
journal article
A conversation with Mary-Claire King.
Published in:
2019
By:
- Neill, Ushma S.
Publication type:
journal article

Found: 46