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Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent-Metabolite Population Pharmacokinetic Model.
Published in:
2016
By:
- Cook, Sarah;
- Stockmann, Chris;
- Samiee-Zafarghandy, Samira;
- King, Amber;
- Deutsch, Nina;
- Williams, Elaine;
- Wilkins, Diana;
- Sherwin, Catherine;
- den Anker, John;
- Cook, Sarah F;
- King, Amber D;
- Williams, Elaine F;
- Wilkins, Diana G;
- Sherwin, Catherine M T;
- van den Anker, John N
Publication type:
journal article
Population pharmacokinetics and dosing optimization of mezlocillin in neonates and young infants.
Published in:
2022
By:
- Zhou, Jing;
- Jiang, Li;
- Zhang, Zhi Ling;
- Wang, Zhao Rui;
- Zhang, Yan Xiu;
- Lin, Xu;
- Tang, Bo Hao;
- Yao, Bu Fan;
- Guo, Zi Xuan;
- Yang, Jing Jing;
- Anker, John Van Den;
- Wu, Yue E;
- Zhao, Wei;
- Van Den Anker, John
Publication type:
journal article
Modeling time‐delayed concentration‐QT effects with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5a1 receptor) antagonist.
Published in:
Pharmacology Research & Perspectives, 2023, v. 11, n. 4, p. 1, doi. 10.1002/prp2.1112
By:
- Anliker‐Ort, Marion;
- Hsin, Chih‐hsuan;
- Krause, Andreas;
- Pfister, Marc;
- van den Anker, John;
- Dingemanse, Jasper;
- Kaufmann, Priska
Publication type:
Article
Different Vancomycin Immunoassays Contribute to the Variability in Vancomycin Trough Measurements in Neonates.
Published in:
BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/1974972
By:
- Samardzic, Janko;
- Smits, Anne;
- Spriet, Isabel;
- Soldatovic, Ivan;
- Atkinson, Andrew;
- Bajcetic, Milica;
- Van Den Anker, John N.;
- Allegaert, Karel
Publication type:
Article
Optimal dose of cefotaxime in neonates with early-onset sepsis: A developmental pharmacokinetic model-based evaluation.
Published in:
Frontiers in Pharmacology, 2022, v. 12, p. 01, doi. 10.3389/fphar.2022.916253
By:
- Zhen-Hai Shang;
- Yue-E Wu;
- Dong-Mei Lv;
- Wei Zhang;
- Wen-Qiang Liu;
- van den Anker, John;
- Yan Xu;
- Wei Zhao
Publication type:
Article
Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs.
Published in:
Pharmaceutics, 2020, v. 12, n. 7, p. 685, doi. 10.3390/pharmaceutics12070685
By:
- Van den Anker, John N.;
- McCune, Susan;
- Annaert, Pieter;
- Baer, Gerri R.;
- Mulugeta, Yeruk;
- Abdelrahman, Ramy;
- Wu, Kunyi;
- Krudys, Kevin M.;
- Fisher, Jeffrey;
- Slikker, William;
- Chen, Connie;
- Burckart, Gilbert J.;
- Allegaert, Karel
Publication type:
Article
Routine Morphine Infusion in Preterm Newborns Who Received Ventilatory Support: A Randomized Controlled Trial.
Published in:
JAMA: Journal of the American Medical Association, 2003, v. 290, n. 18, p. 2419, doi. 10.1001/jama.290.18.2419
By:
- Simons, Sinno H. P.;
- van Dijk, Monique;
- van Lingen, Richard A.;
- Roofthooft, Daniella;
- Duivenvoorden, Hugo J.;
- Jongeneel, Niesje;
- Bunkers, Carin;
- Smink, Enna;
- Anand, K. J. S.;
- van den Anker, John N.;
- Tibboel, Dick
Publication type:
Article
Oral Ibuprofen Is More Effective than Intravenous Ibuprofen for Closure of a Patent Ductus Arteriosus: Can Pharmacokinetic Modeling Help Us to Understand Why?
Published in:
Neonatology (16617800), 2023, v. 120, n. 1, p. 81, doi. 10.1159/000526210
By:
- Smit, Cornelis;
- Engbers, Aline G.J.;
- Samiee-Zafarghandy, Samira;
- van Donge, Tamara;
- Simons, Sinno H.P.;
- Flint, Robert B.;
- Pfister, Marc;
- Knibbe, Catherijne A.J.;
- van den Anker, John N.
Publication type:
Article
Not Only Preterm Neonates Mature but Also Traditional Dosing Regimens Have to Mature: The Role of Mathematical Modeling.
Published in:
Neonatology (16617800), 2021, v. 118, n. 1, p. 114, doi. 10.1159/000513750
By:
- Koch, Gilbert;
- van den Anker, John N.
Publication type:
Article
New Ways to Measure the Effect of Pharmacotherapy in Newborn Infants: Feasible or Not That Much?
Published in:
Neonatology (16617800), 2020, v. 117, n. 4, p. 436, doi. 10.1159/000510058
By:
- van den Anker, John N.
Publication type:
Article
Creatinine at Birth Correlates with Gestational Age and Birth Weight: Another Factor of the Imbroglio in Early Neonatal Life.
Published in:
Neonatology (16617800), 2020, v. 117, n. 5, p. 637, doi. 10.1159/000510658
By:
- Allegaert, Karel;
- Smits, Anne;
- Mekahli, Djalila;
- van den Anker, John N.
Publication type:
Article
Amoxicillin Dosing Regimens for the Treatment of Neonatal Sepsis: Balancing Efficacy and Neurotoxicity.
Published in:
Neonatology (16617800), 2020, v. 117, n. 5, p. 619, doi. 10.1159/000509751
By:
- van Donge, Tamara;
- Fuchs, Aline;
- Leroux, Stéphanie;
- Pfister, Marc;
- Rodieux, Frédérique;
- Atkinson, Andrew;
- Giannoni, Eric;
- van den Anker, John;
- Bielicki, Julia
Publication type:
Article
Acetaminophen Use in Pregnant Women and Their Neonates: Safe or Unsafe till Proven Otherwise?
Published in:
Neonatology (16617800), 2020, v. 117, n. 2, p. 249, doi. 10.1159/000506837
By:
- van den Anker, John N.;
- Allegaert, Karel
Publication type:
Article
Phenobarbital Increases Midazolam Clearance in Neonates Treated with Hypothermia: Do We Really Need to Know?
Published in:
Neonatology (16617800), 2019, v. 116, n. 2, p. 188, doi. 10.1159/000499742
By:
- Allegaert, Karel;
- Smits, Anne;
- van den Anker, John N.
Publication type:
Article
Randomized Controlled Trial Comparing Different Single Doses of Intravenous Paracetamol for Placement of Peripherally Inserted Central Catheters in Preterm Infants.
Published in:
Neonatology (16617800), 2017, v. 112, n. 2, p. 150, doi. 10.1159/000468975
By:
- Roofthooft, Daniella W.E.;
- Simons, Sinno H.P.;
- van Lingen, Richard a.;
- Tibboel, Dick;
- van den anker, John N.;
- Reiss, Irwin K.H.;
- van Dijk, Monique
Publication type:
Article
Clinical Pharmacology in Neonates: Small Size, Huge Variability.
Published in:
Neonatology (16617800), 2014, v. 105, n. 4, p. 344, doi. 10.1159/000360648
By:
- allegaert, Karel;
- van den anker, John N.
Publication type:
Article
The Neonatal European Study of Inhaled Steroids (NEUROSIS): An EU-Funded International Randomised Controlled Trial in Preterm Infants.
Published in:
Neonatology (16617800), 2009, v. 97, n. 1, p. 52
By:
- Bassler, Dirk;
- Halliday, Henry L.;
- Plavka, Richard;
- Hallman, Mikko;
- Shinwell, Eric S.;
- Jarreau, Pierre-Henri;
- Carnielli, Virgilio;
- van den Anker, John;
- Schwab, Matthias;
- Poets, Christian F.
Publication type:
Article
How to translate neurocognitive and behavioural outcome data in animals exposed to paracetamol to the human perinatal setting?
Published in:
Archives of Medical Science, 2024, v. 20, n. 4, p. 1294, doi. 10.5114/aoms.2020.100715
By:
- Allegaert, Karel;
- van den Anker, John
Publication type:
Article
Comorbidity of Migraine and Epilepsy in Pediatrics: A Review.
Published in:
Journal of Child Neurology, 2018, v. 33, n. 12, p. 801, doi. 10.1177/0883073818788942
By:
- Jancic, Jasna;
- Djuric, Vesna;
- Hencic, Boris;
- van den Anker, John N.;
- Samardzic, Janko
Publication type:
Article
Morpholino‐induced exon skipping stimulates cell‐mediated and humoral responses to dystrophin in mdx mice.
Published in:
Journal of Pathology, 2019, v. 248, n. 3, p. 339, doi. 10.1002/path.5263
By:
- Vila, Maria C;
- Novak, James S;
- Benny Klimek, Margaret;
- Li, Ning;
- Morales, Melissa;
- Fritz, Alexander G;
- Edwards, Katie;
- Boehler, Jessica F;
- Hogarth, Marshall W;
- Kinder, Travis B;
- Zhang, Aiping;
- Mazala, Davi;
- Fiorillo, Alyson A;
- Douglas, Bonnie;
- Chen, Yi‐Wen;
- van den Anker, John;
- Lu, Qi L;
- Hathout, Yetrib;
- Hoffman, Eric P;
- Partridge, Terence A
Publication type:
Article
Rising Opioid Prescribing in Adult U.S. Emergency Department Visits: 2001-2010 Incremento en la Prescripción de Opiáceos en las Visitas de Adultos a los Servicios de Urgencias de Estados Unidos: 2001-2010.
Published in:
2014
By:
- Mazer-Amirshahi, Maryann;
- Mullins, Peter M.;
- Rasooly, Irit;
- den Anker, John;
- Pines, Jesse M.
Publication type:
Journal Article
Rising Opioid Prescribing in Adult U.S. Emergency Department Visits: 2001-2010 Incremento en la Prescripción de Opiáceos en las Visitas de Adultos a los Servicios de Urgencias de Estados Unidos: 2001-2010.
Published in:
Academic Emergency Medicine, 2014, v. 21, n. 3, p. 236, doi. 10.1111/acem.12328
By:
- Mazer‐Amirshahi, Maryann;
- Mullins, Peter M.;
- Rasooly, Irit;
- den Anker, John;
- Pines, Jesse M.;
- Miner, James R.
Publication type:
Article
Pharmacogenetic and clinical predictors of ondansetron failure in a diverse pediatric oncology population.
Published in:
Supportive Care in Cancer, 2022, v. 30, n. 4, p. 3513, doi. 10.1007/s00520-022-06818-9
By:
- Jacobs, Shana S.;
- Dome, Jeffrey S.;
- Gai, Jiaxiang;
- Gross, Andrea M.;
- Postell, Elena;
- Hinds, Pamela S.;
- Davenport, Lionel;
- van den Anker, John N.;
- Mowbray, Catriona
Publication type:
Article
Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology.
Published in:
2020
By:
- Schrier, Lenneke;
- Hadjipanayis, Adamos;
- Stiris, Tom;
- Ross-Russell, Rob I;
- Valiulis, Arunas;
- Turner, Mark A;
- Zhao, Wei;
- De Cock, Pieter;
- de Wildt, Saskia N;
- Allegaert, Karel;
- van den Anker, John
Publication type:
journal article
Limited effects of intravenous paracetamol on patent ductus arteriosus in very low birth weight infants with contraindications for ibuprofen or after ibuprofen failure.
Published in:
2015
By:
- Roofthooft, Daniëlla;
- Beynum, Ingrid;
- Klerk, Johan;
- Dijk, Monique;
- Anker, John;
- Reiss, Irwin;
- Tibboel, Dick;
- Simons, Sinno;
- Roofthooft, Daniëlla W E;
- van Beynum, Ingrid M;
- de Klerk, Johan C A;
- van Dijk, Monique;
- van den Anker, John N;
- Reiss, Irwin K M;
- Simons, Sinno H P
Publication type:
journal article
Enzymatic isotope dilution mass spectrometry (IDMS) traceable serum creatinine is preferable over Jaffe in neonates and young infants.
Published in:
Clinical Chemistry & Laboratory Medicine, 2014, v. 52, n. 6, p. e107, doi. 10.1515/cclm-2013-1035
By:
- Allegaert, Karel;
- Pauwels, Steven;
- Smits, Anne;
- Crèvecoeur, Kaat;
- van den Anker, John;
- Mekahli, Djalila;
- Vermeersch, Pieter
Publication type:
Article
Enterobacter Species in a Pediatric Hospital: Horizontal Transfer or Selection in Individual Patients?
Published in:
Journal of Infectious Diseases, 2001, v. 184, n. 2, p. 211, doi. 10.1086/322014
By:
- de Man, Peter;
- van der Veeke, Edwin;
- Leemreijze, Miranda;
- van Leeuwen, Willem;
- Vos, Greet;
- van den Anker, John;
- Verbrugh, Henri;
- van Belkum, Alex
Publication type:
Article
Impact of CYP3A and ABCB1 polymorphisms on the pharmacokinetics and pharmacodynamics of fentanyl.
Published in:
International Journal of Clinical Pharmacology & Therapeutics, 2013, v. 51, n. 12, p. 991, doi. 10.5414/CP201987
By:
- Ziesenitz, Victoria C.;
- van den Anker, John N.
Publication type:
Article
Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children.
Published in:
Scientific Reports, 2016, p. 31727, doi. 10.1038/srep31727
By:
- Hathout, Yetrib;
- Conklin, Laurie S.;
- Seol, Haeri;
- Gordish-Dressman, Heather;
- Brown, Kristy J.;
- Morgenroth, Lauren P.;
- Nagaraju, Kanneboyina;
- Heier, Christopher R.;
- Damsker, Jesse M.;
- van den Anker, John N.;
- Henricson, Erik;
- Clemens, Paula R.;
- Mah, Jean K.;
- McDonald, Craig;
- Hoffman, Eric P.
Publication type:
Article
Editorial: Model-Based Evaluation of Antimicrobial Agents in Children.
Published in:
2021
By:
- Zhao, Wei;
- Wu, Yue-E;
- van den Anker, John
Publication type:
Editorial
Serum Creatinine and Serum Cystatin C are Both Relevant Renal Markers to Estimate Vancomycin Clearance in Critically Ill Neonates.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.634686
By:
- Leroux, Stéphanie;
- Biran, Valérie;
- van den Anker, John;
- Gotta, Verena;
- Zhao, Wei;
- Zhang, Daolun;
- Jacqz-Aigrain, Evelyne;
- Pfister, Marc
Publication type:
Article
Population Pharmacokinetic Study of Cefathiamidine in Infants With Augmented Renal Clearance.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.630047
By:
- Du, Bin;
- Zhou, Yue;
- Tang, Bo-Hao;
- Wu, Yue-E;
- Yang, Xin-Mei;
- Shi, Hai-Yan;
- Yao, Bu-Fan;
- Hao, Guo-Xiang;
- You, Dian-Ping;
- van den Anker, John;
- Zheng, Yi;
- Zhao, Wei
Publication type:
Article
Creatinine Trends to Detect Ibuprofen-Related Maturational Adverse Drug Events in Neonatal Life: A Simulation Study for the ELBW Newborn.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.610294
By:
- van Donge, Tamara;
- Allegaert, Karel;
- Pfister, Marc;
- Smits, Anne;
- van den Anker, John
Publication type:
Article
Elusive sources of variability of dystrophin rescue by exon skipping.
Published in:
Skeletal Muscle, 2015, v. 5, p. 1, doi. 10.1186/s13395-015-0070-6
By:
- Vila, Maria Candida;
- Klimek, Margaret Benny;
- Novak, James S.;
- Rayavarapu, Sree;
- Uaesoontrachoon, Kitipong;
- Boehler, Jessica F.;
- Fiorillo, Alyson A.;
- Hogarth, Marshall W.;
- Aiping Zhang;
- Shaughnessy, Conner;
- Gordish-Dressman, Heather;
- Burki, Umar;
- Straub, Volker;
- Qi Long Lu;
- Partridge, Terence A.;
- Brown, Kristy J.;
- Hathout, Yetrib;
- van den Anker, John;
- Hoffman, Eric P.;
- Nagaraju, Kanneboyina
Publication type:
Article
Population pharmacokinetic modeling to facilitate dose selection of tapentadol in the pediatric population.
Published in:
Journal of Pain Research, 2019, v. 12, p. 2835, doi. 10.2147/JPR.S208454
By:
- Watson, Estelle;
- Khandelwal, Akash;
- Freijer, Jan;
- van den Anker, John;
- Lefeber, Claudia;
- Eerdekens, Mariëlle
Publication type:
Article
Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to <18 years – a randomized, double-blind, placebo-controlled trial.
Published in:
Journal of Pain Research, 2019, v. 12, p. 3099, doi. 10.2147/JPR.S207010
By:
- Beuter, Christoph;
- Volkers, Gisela;
- Radic, Tatjana;
- Goldberg, Jutta;
- van den Anker, John
Publication type:
Article
The challenge of developing pain medications for children: therapeutic needs and future perspectives.
Published in:
Journal of Pain Research, 2019, v. 12, p. 1649, doi. 10.2147/JPR.S195788
By:
- Eerdekens, Mariëlle;
- Beuter, Christoph;
- Lefeber, Claudia;
- van den Anker, John
Publication type:
Article
A Population Model of Time-Dependent Changes in Serum Creatinine in (Near)term Neonates with Hypoxic-Ischemic Encephalopathy During and After Therapeutic Hypothermia.
Published in:
AAPS Journal, 2024, v. 26, n. 1, p. 1, doi. 10.1208/s12248-023-00851-0
By:
- Krzyzanski, Wojciech;
- Wintermark, Pia;
- Annaert, Pieter;
- Groenendaal, Floris;
- Şahin, Suzan;
- Öncel, Mehmet Yekta;
- Armangil, Didem;
- Koc, Esin;
- Battin, Malcolm R.;
- Gunn, Alistair J.;
- Frymoyer, Adam;
- Chock, Valerie Y.-L.;
- Keles, Elif;
- Mekahli, Djalila;
- van den Anker, John;
- Smits, Anne;
- Allegaert, Karel
Publication type:
Article
Population Model of Serum Creatinine as Time-Dependent Covariate in Neonates.
Published in:
AAPS Journal, 2021, v. 23, n. 4, p. 1, doi. 10.1208/s12248-021-00612-x
By:
- Krzyzanski, Wojciech;
- Smits, Anne;
- Van Den Anker, John;
- Allegaert, Karel
Publication type:
Article
Population Pharmacokinetic Modeling in the Presence of Missing Time-Dependent Covariates: Impact of Body Weight on Pharmacokinetics of Paracetamol in Neonates.
Published in:
AAPS Journal, 2019, v. 21, n. 4, p. N.PAG, doi. 10.1208/s12248-019-0331-0
By:
- Krzyzanski, Wojciech;
- Cook, Sarah F.;
- Wilbaux, Melanie;
- Sherwin, Catherine M. T.;
- Allegaert, Karel;
- Vermeulen, An;
- van den Anker, John N.
Publication type:
Article
Longitudinal trends in U.S. shortages of sterile solutions, 2001-17.
Published in:
American Journal of Health-System Pharmacy, 2018, v. 75, n. 23, p. 1903, doi. 10.2146/ajhp180203
By:
- Maryann, Mazer-Amirshahi;
- R., Fox Erin;
- S., Zocchi Mark;
- M., Pines Jesse;
- N., van den Anker John
Publication type:
Article
Impact of ontogeny on linezolid disposition in neonates and infants*.
Published in:
Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 5, p. 413, doi. 10.1016/S0009-9236(03)00226-1
By:
- Kearns, Gregory L.;
- Jungbluth, Gail L.;
- Abdel-Rahman, Susan M.;
- Hopkins, Nancy K.;
- Welshman, Ian R.;
- Grzebyk, Rosie P.;
- Bruss, Jon B.;
- van den Anker, John N.
Publication type:
Article
Cisapride disposition in neonates and infants: in vivo reflection of cytochrome P450 3A4 ontogeny*.
Published in:
Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 4, p. 312, doi. 10.1016/S0009-9236(03)00225-X
By:
- Kearns, Gregory L.;
- Robinson, Patricia K.;
- Wilson, John T.;
- Wilson-Costello, Deanna;
- Knight, Gail R.;
- Ward, Robert M.;
- van den Anker, John N.
Publication type:
Article
Cisapride: A potential model substrate to assess cytochrome P4503A4 activity in vivo*.
Published in:
Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 3, p. 209, doi. 10.1067/mcp.2003.29
By:
- Lowry, Jennifer A.;
- Kearns, Gregory L.;
- Abdel-Rahman, Susan M.;
- Nafziger, Anne N.;
- Khan, Irim S.;
- Kashuba, Angela D. M.;
- Schuetz, Erin G.;
- Bertino, Joseph S.;
- van den Anker, John N.;
- Leeder, J. Steven
Publication type:
Article
Extended-interval dosing of tobramycin in neonates: Implications for therapeutic drug monitoring.
Published in:
Clinical Pharmacology & Therapeutics, 2002, v. 71, n. 5, p. 349, doi. 10.1067/mcp.2002.123595
By:
- de Hoog, Matthijs;
- Mouton, Johan W.;
- Schoemaker, Rik C.;
- Verduin, Cees M.;
- van den Anker, John N.
Publication type:
Article
Ibuprofen pharmacokinetics in preterm infants with patent ductus arteriosus.
Published in:
Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 4, p. 336, doi. 10.1016/S0009-9236(01)13478-8
By:
- Van Overmeire, Bart;
- Touw, Daan;
- Schepens, Paul J. C.;
- Kearns, Gregory L.;
- van den Anker, John N.
Publication type:
Article
Vancomycin population pharmacokinetics in neonates.
Published in:
Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 4, p. 360, doi. 10.1067/mcp.2000.105353
By:
- de Hoog, Matthijs;
- Schoemaker, Rik C.;
- Mouton, Johan W.;
- van den Anker, John N.
Publication type:
Article
Tobramycin population pharmacokinetics in neonates*.
Published in:
Clinical Pharmacology & Therapeutics, 1997, v. 62, n. 4, p. 392, doi. 10.1016/S0009-9236(97)90117-X
By:
- de Hoog, Matthijs;
- Schoemaker, Rik C.;
- Mouton, Johan W.;
- van den Anker, John N.
Publication type:
Article
Ceftazidime pharmacokinetics in preterm infants: Effects of renal function and gestational age*.
Published in:
Clinical Pharmacology & Therapeutics, 1995, v. 58, n. 6, p. 650, doi. 10.1016/0009-9236(95)90021-7
By:
- van den Anker, John N.;
- Schoemaker, Rik C.;
- Hop, Wim C. J.;
- van der Heijden, Bert J.;
- Weber, Allan;
- Sauer, Pieter J. J.;
- Neijens, Herman J.;
- de Groot, Ronald
Publication type:
Article
Efficacy and Safety of Vasopressin and Terlipressin in Preterm Neonates: A Systematic Review.
Published in:
International Journal of Environmental Research & Public Health, 2022, v. 19, n. 21, p. 13760, doi. 10.3390/ijerph192113760
By:
- Al-Saadi, Abdulrahman;
- Sushko, Katelyn;
- Bui, Vivian;
- van den Anker, John;
- Razak, Abdul;
- Samiee-Zafarghandy, Samira
Publication type:
Article

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