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- Title
Caffeine and Its Pharmacological Benefits in the Management of Androgenetic Alopecia: A Review.
- Authors
Völker, Jörn Michael; Koch, Nadine; Becker, Maike; Klenk, Adolf
- Abstract
Caffeine, particularly after ingestion, is well known to exert various pharmacological effects. A growing body of evidence implicates the ingestion of caffeine with beneficial effects on several diseases. The easy penetration of caffeine across the skin barrier and into human skin makes caffeine an ideal compound for topical application. Hair loss is known to negatively affect the quality of life and predispose to depression and anxiety. Androgenetic alopecia (AGA) is the most common type of hair loss in both men and women. To date, only few approved drug-based treatments for AGA exist, and these are inevitably associated with side effects. Therefore, the development of topical treatments based on well-tolerated natural ingredients such as caffeine to alleviate hair loss may provide a much-needed alternative to drug-based approaches.
- Subjects
CAFFEINE; BALDNESS; PHARMACOLOGY; INGESTION; SKIN; QUALITY of life; ANXIETY; MENTAL depression
- Publication
Skin Pharmacology & Physiology, 2020, Vol 33, Issue 3, p93
- ISSN
1660-5527
- Publication type
Academic Journal
- DOI
10.1159/000508228