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- Title
Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population.
- Authors
Kim, Tae-Joon; Yoon, Jee Eun; Park, Jung A; Lee, Seung Ku; Chu, Min Kyung; Yang, Kwang Ik; Kim, Won-Joo; Park, Seong-Ho; Thomas, Robert J.; Shin, Chol; Yun, Chang-Ho
- Abstract
<bold><italic>Background:</italic></bold> Restless legs syndrome (RLS) is a common sleep disorder, although it has a low prevalence in Asian populations. However, the reported RLS prevalence in -Korean adults is mostly 4.5–12.1%, which is higher than that reported in other Asian populations. This study aimed to diagnose RLS and exclude mimicking conditions in 2 independent samples of Korean adults, and to compare its prevalence to that from previous studies performed in Asian countries. <bold><italic>Methods:</italic></bold> Study populations included a (1) nationwide stratified random sample (<italic>n</italic> = 2,824; age 19–79 years) and (2) community-based cohort (<italic>n</italic> = 2,685; age 47–79 years). We applied the Cambridge-Hopkins diagnostic questionnaire to diagnose RLS and differentiate it from RLS mimics. Sleep-related symptoms, mood, and medical conditions were compared between the RLS and non-RLS groups. Prior studies of the RLS prevalence in Asia were systematically reviewed and compared to our findings. <bold><italic>Results:</italic></bold> The adjusted RLS prevalence was 0.4 and 1.3% in populations 1 and 2, respectively. In both populations, subjects with RLS had more depression. The prevalence of RLS mimics was 5.1 and 2.6%, in populations 1 and 2, respectively. The RLS prevalence in Asia was higher when RLS was defined by the presence of essential clinical features and lower when a differential diagnosis was additionally implemented. <bold><italic>Conclusions:</italic></bold> The RLS prevalence in Korean adults considering RLS mimics is comparable to that in adults from other Asian countries (< 2%). The reported RLS prevalence varies depending on the diagnostic method employed.
- Publication
Neuroepidemiology, 2019, Vol 52, Issue 3/4, p193
- ISSN
0251-5350
- Publication type
Academic Journal
- DOI
10.1159/000496839