Works matching DE "CELLULAR aging"

Results: 5000

STMN1–IGFBP5 axis induces senescence and extracellular matrix degradation in nucleus pulposus cells: In vivo and in vitro insights.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01220-7

By:

Li, Lei;
Zhang, Guangzhi;
Yang, Zhili;
Cao, Zhenyu;
Wang, Dongxin;
Kang, Xuewen

Publication type:

Article

Non-Canonical STING-PERK Pathway Modulation of Cellular Senescence and Therapeutic Response in Sepsis-Associated Acute Kidney Injury.

Published in:

Inflammation, 2025, v. 48, n. 2, p. 696, doi. 10.1007/s10753-024-02081-8

By:

Dong, Yuxin;
Liu, Guanghe;
Situ, Xiaonan;
Xia, Lei;
Zhang, Tianyi;
Zhu, Xiangxi;
Jin, Heng;
Liu, Yancun;
Shou, Songtao

Publication type:

Article

Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders.

Published in:

PLoS Computational Biology, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.pcbi.1012382

By:

Osbourne, Romani;
Thayer, Kelly M.

Publication type:

Article

Genetic ablation of p16 mitigates premature osteoporosis induced by PTHrP nuclear localization sequence and C-terminal deletion through inhibition of cellular senescence.

Published in:

Stem Cells, 2025, v. 43, n. 4, p. 1, doi. 10.1093/stmcls/sxae088

By:

Han, Yongli;
Qiao, Wanxin;
Xue, Qi;
Miao, Dengshun;
Dong, Zhan

Publication type:

Article

Quercetin ameliorates ox-LDL-induced cellular senescence of aortic endothelial cells and macrophages by p16/p21, p53/SERPINE1, and AMPK/mTOR pathways.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02562-y

By:

Liang, Xiao;
Zhang, Jingyuan;
Yu, Jiangbo;
Zhao, Jiyi;
Yang, Shusen

Publication type:

Article

Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts.

Published in:

Skin Pharmacology & Physiology, 2021, v. 34, n. 4, p. 194, doi. 10.1159/000514496

By:

Wu, Yun;
Cao, Kun;
Zhang, Wei;
Zhang, Guangxian;
Zhou, Maojun

Publication type:

Article

DCP-LA Exerts an Antiaging Action on the Skin.

Published in:

Skin Pharmacology & Physiology, 2016, v. 29, n. 3, p. 157, doi. 10.1159/000446216

By:

Nishizaki, Tomoyuki

Publication type:

Article

A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation.

Published in:

PLoS Biology, 2010, v. 8, n. 9, p. 1, doi. 10.1371/journal.pbio.1000476

By:

Besancenot, Rodolphe;
Chaligné, Ronan;
Tonetti, Carole;
Pasquier, Florence;
Marty, Caroline;
Lécluse, Yann;
Vainchenker, William;
Constantinescu, Stefan N.;
Giraudier, Stéphane

Publication type:

Article

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor.

Published in:

PLoS Biology, 2008, v. 6, n. 12, p. e301, doi. 10.1371/journal.pbio.0060301

By:

Coppé, Jean-Philippe;
Patil, Christopher K.;
Rodier, Francis;
Yu Sun;
Muñoz, Denise P.;
Goldstein, Joshua;
Nelson, Peter S.;
Desprez, Pierre-Yves;
Campisi, Judith

Publication type:

Article

Mechanisms of Aging in Bone Marrow Stem Cells.

Published in:

PLoS Biology, 2007, v. 5, n. 8, p. 1637, doi. 10.1371/journal.pbio.0050215

By:

Gross, Liza

Publication type:

Article

The Cell Nucleus and Aging: Tantalizing Clues and Hopeful Promises.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0030395

By:

Scaffidi, Paola;
Gordon, Leslie;
Misteli, Tom

Publication type:

Article

Telomere length and telomerase activity in the context of menopause.

Published in:

Climacteric, 2013, v. 16, n. 6, p. 629, doi. 10.3109/13697137.2013.812603

By:

Pines, A.

Publication type:

Article

Validation of signalling pathways: Case study of the p16-mediated pathway.

Published in:

Journal of Bioinformatics & Computational Biology, 2015, v. 13, n. 2, p. -1, doi. 10.1142/S0219720015500079

By:

Akçay, Nimet İlke;
Bashirov, Rza;
Tüzmen, Şükrü

Publication type:

Article

Modified Peptide Molecules As Potential Modulators of Shelterin Protein Functions; TRF1.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 55, p. 1, doi. 10.1002/chem.202300970

By:

Brankiewicz, Wioletta;
Kalathiya, Umesh;
Padariya, Monikaben;
Węgrzyn, Katarzyna;
Prusinowski, Maciej;
Zebrowska, Joanna;
Zylicz‐Stachula, Agnieszka;
Skowron, Piotr;
Drab, Marek;
Szajewski, Mariusz;
Ciesielski, Maciej;
Gawrońska, Małgorzata;
Kallingal, Anoop;
Makowski, Mariusz;
Bagiński, Maciej

Publication type:

Article

QTL mapping for leaf senescence-related traits in common wheat under limited and full irrigation.

Published in:

Euphytica, 2015, v. 203, n. 3, p. 569, doi. 10.1007/s10681-014-1272-4

By:

Li, Xing-Mao;
He, Zhong-Hu;
Xiao, Yong-Gui;
Xia, Xian-Chun;
Trethowan, Richard;
Wang, Hua-Jun;
Chen, Xin-Min

Publication type:

Article

Internalization of the TAT-PBX1 fusion protein significantly enhances the proliferation of human hair follicle-derived mesenchymal stem cells and delays their senescence.

Published in:

Biotechnology Letters, 2020, v. 42, n. 10, p. 1877, doi. 10.1007/s10529-020-02909-x

By:

Wang, Bo;
Liu, Feilin;
Liu, Zinan;
Han, Xing;
Lian, Aobo;
Zhang, Yuying;
Zuo, Kuiyang;
Wang, Yuan;
Liu, Mingsheng;
Zou, Fei;
Jiang, Yixu;
Jin, Minghua;
Liu, Xiaomei;
Liu, Jinyu

Publication type:

Article

Cell-level anatomy explains leaf age-dependent declines in mesophyll conductance and photosynthetic capacity in the evergreen Mediterranean oak Quercus ilex subsp. rotundifolia.

Published in:

Tree Physiology, 2022, v. 42, n. 10, p. 1988, doi. 10.1093/treephys/tpac049

By:

Alonso-Forn, David;
Peguero-Pina, José Javier;
Ferrio, Juan Pedro;
García-Plazaola, José Ignacio;
Martín-Sánchez, Rubén;
Niinemets, Ülo;
Sancho-Knapik, Domingo;
Gil-Pelegrín, Eustaquio

Publication type:

Article

meristem-associated endosymbiont Methylorubrum extorquens DSM13060 reprograms development and stress responses of pine seedlings.

Published in:

Tree Physiology, 2022, v. 42, n. 2, p. 391, doi. 10.1093/treephys/tpab102

By:

Koskimäki, Janne J;
Pohjanen, Johanna;
Kvist, Jouni;
Fester, Thomas;
Härtig, Claus;
Podolich, Olga;
Fluch, Silvia;
Edesi, Jaanika;
Häggman, Hely;
Pirttilä, Anna Maria

Publication type:

Article

In renal proximal tubular epithelial cells of the hibernator Syrian hamster, anoxia-reoxygenation-induced reactive oxygen species bursts do not trigger a DNA damage response and cellular senescence.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2025, v. 195, n. 1, p. 91, doi. 10.1007/s00360-025-01604-5

By:

Pissas, Georgios;
Divani, Maria;
Tziastoudi, Maria;
Poulianiti, Christina;
Polyzou-Konsta, Maria-Anna;
Lykotsetas, Evangelos;
Stefanidis, Ioannis;
Eleftheriadis, Theodoros

Publication type:

Article

Impact of a nutritional supplement during gestation and early childhood on child salivary cortisol, hair cortisol, and telomere length at 4–6 years of age: a follow-up of a randomized controlled trial.

Published in:

2020

By:

Oaks, Brietta M.;
Adu-Afarwuah, Seth;
Kumordzie, Sika;
Laudenslager, Mark L.;
Smith, Dana L.;
Lin, Jue;
Young, Rebecca R.;
Arnold, Charles D.;
Bentil, Helena;
Okronipa, Harriet;
Ocansey, Maku;
Dewey, Kathryn G.

Publication type:

Report

Alternative lengthening of telomeres in molecular subgroups of paediatric high-grade glioma.

Published in:

Child's Nervous System, 2021, v. 37, n. 3, p. 809, doi. 10.1007/s00381-020-04933-8

By:

Minasi, Simone;
Baldi, Caterina;
Gianno, Francesca;
Antonelli, Manila;
Buccoliero, Anna Maria;
Pietsch, Torsten;
Massimino, Maura;
Buttarelli, Francesca Romana

Publication type:

Article

The relationship between telomere length and aging-related diseases.

Published in:

2025

By:

Huang, Xuanqi;
Huang, Leyi;
Lu, Jiaweng;
Cheng, Lijuan;
Wu, Du;
Li, Linmeng;
Zhang, Shuting;
Lai, Xinyue;
Xu, Lu

Publication type:

Literature Review

Addendum to 13th International Congress on Amino Acids, Peptides and Protein.

Published in:

Amino Acids, 2014, v. 46, n. 1, p. 251, doi. 10.1007/s00726-013-1634-6

By:

Wu, Guoyao

Publication type:

Article

Oxidative Stress, Telomere Length and Telomerase Activity in Spermatogenesis Disorders (Review of Scientific Activity).

Published in:

Bulletin of Experimental Biology & Medicine, 2023, v. 176, n. 2, p. 115, doi. 10.1007/s10517-024-05979-3

By:

Kurashova, N. A.;
Dashiev, B. G.;
Kolesnikov, S. I.;
Kolesnikova, L. I.

Publication type:

Article

Peptide KED: Molecular-Genetic Aspects of Neurogenesis Regulation in Alzheimer's Disease.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 171, n. 2, p. 190, doi. 10.1007/s10517-021-05192-6

By:

Khavinson, V. Kh.;
Lin'kova, N. S.;
Umnov, R. S.

Publication type:

Article

Expression of Aβ42, τ-Protein, p16, p53 in Buccal Epithelium: Prospects for Use in the Diagnostics of Alzheimer's Disease and Rate of Aging.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 676, doi. 10.1007/s10517-019-04416-0

By:

Zuev, V. A.;
Dyatlova, A. S.;
Lin'kova, N. S.;
Kvetnaya, T. V.

Publication type:

Article

Expression of Aβ42, τ-Protein, p16, p53 in Buccal Epithelium: Prospects for Use in the Diagnostics of Alzheimer's Disease and Rate of Aging.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 5, p. 676, doi. 10.1007/s10517-019-04416-0

By:

Zuev, V. A.;
Dyatlova, A. S.;
Lin'kova, N. S.;
Kvetnaya, T. V.

Publication type:

Article

Age-Related Changes in the System Metalloproteinases/Tissue Metalloproteinase Inhibitors and Proteoglycan Components in Mouse Organs.

Published in:

Bulletin of Experimental Biology & Medicine, 2016, v. 161, n. 1, p. 32, doi. 10.1007/s10517-016-3338-x

By:

Kim, L.;
Shkurupy, V.;
Putyatina, A.

Publication type:

Article

Peptide Regulation of Skin Fibroblast Functions during Their Aging In Vitro.

Published in:

Bulletin of Experimental Biology & Medicine, 2016, v. 161, n. 1, p. 175, doi. 10.1007/s10517-016-3370-x

By:

Lin'kova, N.;
Drobintseva, A.;
Orlova, O.;
Kuznetsova, E.;
Polyakova, V.;
Kvetnoy, I.;
Khavinson, V.

Publication type:

Article

Ultrastructural Changes in Ageing Lacrimal Gland in Wistar Rats.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 157, n. 2, p. 268, doi. 10.1007/s10517-014-2542-9

By:

Vais, V.;
Vangeli, I.;
Bakeeva, L.

Publication type:

Article

Mathematical Modeling of Functioning of the p53-Mdm2 Protein System.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 157, n. 2, p. 291, doi. 10.1007/s10517-014-2548-3

By:

Voropaeva, O.;
Shokin, Yu.;
Nepomnyashchikh, L.;
Senchukova, S.

Publication type:

Article

Peptides Regulate Expression of Signaling Molecules in Kidney Cell Cultures during In Vitro Aging.

Published in:

Bulletin of Experimental Biology & Medicine, 2014, v. 157, n. 2, p. 261, doi. 10.1007/s10517-014-2540-y

By:

Khavinson, V.;
Lin'kova, N.;
Polyakova, V.;
Durnova, A.;
Nichik, T.;
Kvetnoi, I.

Publication type:

Article

Astragaloside IV ameliorates radiation‐induced senescence via antioxidative mechanism.

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 8, p. 1110, doi. 10.1111/jphp.13284

By:

Liu, Xin;
Shang, Shuying;
Chu, Weiwei;
Ma, Liang;
Jiang, Chenxin;
Ding, Yanping;
Wang, Jianlin;
Zhang, Shengxiang;
Shao, Baoping

Publication type:

Article

پیری سلولی زودرس در کندروسیتهای جدا شده از غضروف انگشتان پلیداكتیلی در محیط حاوی سرم جنین گاوی در مقایسه با سرم انسانی.

Published in:

Medical Journal of Tabriz University of Medical Sciences, 2022, v. 43, n. 6, p. 497, doi. 10.34172/mj.2022.002

By:

هاجر شفائی;
اعظم فارانی;
زهرا بقائی;
اطمه مرتضوی

Publication type:

Article

Expression of Lamin A gene in periodontitis: A cross-sectional study.

Published in:

Journal of Advanced Periodontology & Implant Dentistry, 2025, v. 17, n. 1, p. 36, doi. 10.34172/japid.2025.003

By:

Sargolzaie, Naser;
Tavakkol-Afshari, Jalil;
Mohebati, Raziyeh;
Basiri, Faeze;
Shahri, Arsalan;
Fasihi Ramandi, Mahdiye

Publication type:

Article

Effect of Genistein on Scopolamine Induced Dementia in Mice.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 1, p. 154, doi. 10.21608/ZUMJ.2023.216419.2809

By:

Rofaeel, Mariam Botros;
Ayad, Nada Hashem;
Abou El-Noeman, Saad El-Din Abd El-Fattah;
Gaber, Rasha Ahmed

Publication type:

Article

Cell Senescence and the DNA Single-Strand Break Damage Repair Pathway.

Published in:

DNA (2673-8856), 2024, v. 4, n. 4, p. 530, doi. 10.3390/dna4040036

By:

Sarma, Parvathy A.;
Abbadie, Corinne;
de Launoit, Yvan;
Cleri, Fabrizio

Publication type:

Article

A Dual-Labeled Multiplex Absolute Telomere Length Method to Measure Average Telomere Length.

Published in:

DNA (2673-8856), 2024, v. 4, n. 4, p. 370, doi. 10.3390/dna4040026

By:

Rutherford Siegel, Sue;
Calcagni, E. Alex;
Draughon, Kelsey M.;
Logue, Sheree F.

Publication type:

Article

Senescence-associated secretory phenotype constructed detrimental and beneficial subtypes and prognostic index for prostate cancer patients undergoing radical prostatectomy.

Published in:

Discover Oncology, 2023, v. 14, n. 1, p. 1, doi. 10.1007/s12672-023-00777-1

By:

Feng, Dechao;
Wang, Jie;
Li, Dengxiong;
Wu, Ruicheng;
Wei, Wuran;
Zhang, Chi

Publication type:

Article

Induction of chronic asthma up regulated the transcription of senile factors in male rats.

Published in:

BMC Molecular & Cell Biology, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12860-024-00518-4

By:

Hassanzadeh-Khanmiri, Majid;
Keyhanmanesh, Rana;
Mosaddeghi-Heris, Reza;
Delkhosh, Aref;
Rezaie, Jafar;
Taghizadeh, Sajjad;
Sara, Mehdi Rezai Seghin;
Ahmadi, Mahdi

Publication type:

Article

Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00435-4

By:

Berenjabad, Nesa Janamo;
Nejati, Vahid;
Rezaie, Jafar

Publication type:

Article

Angiogenic ability of human endothelial cells was decreased following senescence induction with hydrogen peroxide: possible role of vegfr-2/akt-1 signaling pathway.

Published in:

BMC Molecular & Cell Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12860-022-00435-4

By:

Berenjabad, Nesa Janamo;
Nejati, Vahid;
Rezaie, Jafar

Publication type:

Article

Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation.

Published in:

BMC Molecular & Cell Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12860-020-00326-6

By:

Gottwald, Dorian;
Putz, Florian;
Hohmann, Nora;
Büttner-Herold, Maike;
Hecht, Markus;
Fietkau, Rainer;
Distel, Luitpold

Publication type:

Article

Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells.

Published in:

BMC Molecular & Cell Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12860-020-00292-z

By:

Li, Yan;
Liu, Yong;
Wang, Kailong;
Huang, Yinghui;
Han, Wenhao;
Xiong, Jiachuan;
Yang, Ke;
Liu, Mingying;
Xiao, Tangli;
Liu, Chi;
He, Ting;
Bi, Xianjin;
Zhang, Jingbo;
Zhang, Bo;
Zhao, Jinghong

Publication type:

Article

The Combination of Sorafenib and PGV‐1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c‐Myc Suppression in an Additive Manner: In Vitro Studies.

Published in:

Advances in Pharmacological & Pharmaceutical Sciences, 2024, v. 2024, p. 1, doi. 10.1155/adpp/4297953

By:

Novitasari, Dhania;
Nakamae, Ikuko;
Yoneda-Kato, Noriko;
Kato, Jun-ya;
Hippo, Yoshitaka;
Suenaga, Yusuke;
Putri, Dyaningtyas Dewi Pamungkas;
Meiyanto, Edy;
Ikawati, Muthi';
Ooi, Der Jiun

Publication type:

Article

Ebselen, Iron Uptake Inhibitor, Alleviates Iron Overload-Induced Senescence-Like Neuronal Cells SH-SY5Y via Suppressing the mTORC1 Signaling Pathway.

Published in:

Advances in Pharmacological & Pharmaceutical Sciences, 2023, p. 1, doi. 10.1155/2023/6641347

By:

Mukem, Sirirak;
Sayoh, Ibrahim;
Maungchanburi, Saowanee;
Thongbuakaew, Tipsuda

Publication type:

Article

Посттравматичний стресовий розлад і метаболічний синдром: роль деяких антиоксидантів у лікуванні.

Published in:

International Journal of Endocrinology / Mìžnarodnij Endokrinologìčnij Žurnal, 2024, v. 20, n. 6, p. 470, doi. 10.22141/2224-0721.20.6.2024.1445

By:

В. О., Сергієнко;
А. Ю., Олійник;
Я. І., Павловський;
О. С., Крук;
О. О., Сергієнко

Publication type:

Article

Integrative modeling uncovers p21-driven drug resistance and prioritizes therapies for PIK3CA-mutant breast cancer.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00496-y

By:

Yip, Hon Yan Kelvin;
Shin, Sung-Young;
Chee, Annabel;
Ang, Ching-Seng;
Rossello, Fernando J.;
Wong, Lee Hwa;
Nguyen, Lan K.;
Papa, Antonella

Publication type:

Article

Phase separation of MRG15 delays cellular senescence.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08071-2

By:

Li, Yuwen;
Jin, Xinrong;
Yu, Chunyu;
Zuo, Min;
Hong, Liquan;
Wang, Mingwei;
Zhao, Chenyan;
Wu, Aiwei;
Wang, Jianjun;
Ju, Zhenyu;
Wang, Hu

Publication type:

Article

Recruiting adaptive cellular stress responses for successful brain ageing.

Published in:

Nature Reviews Neuroscience, 2012, v. 13, n. 3, p. 209, doi. 10.1038/nrn3151

By:

Stranahan, Alexis M.;
Mattson, Mark P.

Publication type:

Article