Title: Antibacterial Activity of Cold Atmospheric Pressure Argon Plasma against 78 Genetically Different (mecA, luk-P, agr or Capsular Polysaccharide Type) Staphylococcus aureus Strains.
Authors: Matthes, Rutger; Lührman, anne; Holtfreter, Silva; Kolata, Julia; Radke, Dörte; Hübner, Nils-Olaf; assadian, Ojan; Kramer, axel
Abstract: Previous studies on the antimicrobial activity of cold atmospheric pressure argon plasma showed varying effects against mecA or mecA - Staphylococcus aureus strains. This observation may have important clinical and epidemiological implications. Here, the antibacterial activity of argon plasma was investigated against 78 genetically different S. aureus strains, stratified by mecA, luk-P, agr1-4, or the cell wall capsule polysaccharide types 5 and 8. kINPen09 ® served as the plasma source for all experiments. On agar plates, mecA luk-P - S. aureus strains showed a decreased susceptibility against plasma compared to other S. aureus strains. This study underlines the high complexity of microbial defence against antimicrobial treatment and confirms a previously reported strain-dependent susceptibility of S. aureus to plasma treatment.
Subjects: ARGON plasmas; ANTI-infective agents; ATMOSPHERIC pressure; STAPHYLOCOCCUS aureus; POLYSACCHARIDES
Publication: Skin Pharmacology & Physiology, 2016, Vol 29, Issue 2, p83
ISSN: 1660-5527
Publication type: Academic Journal
DOI: 10.1159/000443210

Antibacterial Activity of Cold Atmospheric Pressure Argon Plasma against 78 Genetically Different (mecA, luk-P, agr or Capsular Polysaccharide Type) Staphylococcus aureus Strains.

Matthes, Rutger; Lührman, anne; Holtfreter, Silva; Kolata, Julia; Radke, Dörte; Hübner, Nils-Olaf; assadian, Ojan; Kramer, axel