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- Title
Antibacterial Activity of Cold Atmospheric Pressure Argon Plasma against 78 Genetically Different (mecA, luk-P, agr or Capsular Polysaccharide Type) Staphylococcus aureus Strains.
- Authors
Matthes, Rutger; Lührman, anne; Holtfreter, Silva; Kolata, Julia; Radke, Dörte; Hübner, Nils-Olaf; assadian, Ojan; Kramer, axel
- Abstract
Previous studies on the antimicrobial activity of cold atmospheric pressure argon plasma showed varying effects against mecA or mecA - Staphylococcus aureus strains. This observation may have important clinical and epidemiological implications. Here, the antibacterial activity of argon plasma was investigated against 78 genetically different S. aureus strains, stratified by mecA, luk-P, agr1-4, or the cell wall capsule polysaccharide types 5 and 8. kINPen09 ® served as the plasma source for all experiments. On agar plates, mecA luk-P - S. aureus strains showed a decreased susceptibility against plasma compared to other S. aureus strains. This study underlines the high complexity of microbial defence against antimicrobial treatment and confirms a previously reported strain-dependent susceptibility of S. aureus to plasma treatment.
- Subjects
ARGON plasmas; ANTI-infective agents; ATMOSPHERIC pressure; STAPHYLOCOCCUS aureus; POLYSACCHARIDES
- Publication
Skin Pharmacology & Physiology, 2016, Vol 29, Issue 2, p83
- ISSN
1660-5527
- Publication type
Academic Journal
- DOI
10.1159/000443210