Works matching DE "AMYLOID beta-protein precursor"
Results: 3178
hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies.
- Published in:
- Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 732, doi. 10.1038/nsmb.1815
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- Article
Translational symphony in (hnRNP) C major for APP.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 6, p. 675, doi. 10.1038/nsmb0610-675
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- Publication type:
- Article
Substrate check of γ-secretase.
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- Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 140, doi. 10.1038/nsmb0210-140
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- Article
Lecanemab in Alzheimer's disease: a profile of its use.
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- Drugs & Therapy Perspectives, 2024, v. 40, n. 10, p. 393, doi. 10.1007/s40267-024-01108-2
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- Publication type:
- Article
Season of birth and vulnerability to the pathology of Alzheimer's disease: an in vivo positron emission tomography study.
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- Psychogeriatrics, 2022, v. 22, n. 4, p. 445, doi. 10.1111/psyg.12838
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- Article
Empirically defining the preclinical stages of the Alzheimer's continuum in the Alzheimer's Disease Neuroimaging Initiative.
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- Psychogeriatrics, 2021, v. 21, n. 4, p. 491, doi. 10.1111/psyg.12697
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- Publication type:
- Article
An evaluation of the amyloid cascade model using in vivo positron emission tomographic imaging.
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- Psychogeriatrics, 2021, v. 21, n. 1, p. 14, doi. 10.1111/psyg.12589
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- Publication type:
- Article
Active Site Environment and Reactivity of Copper‐Aβ in Membrane Mimetic SDS Micellar Environment.
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- Chemistry - A European Journal, 2024, v. 30, n. 51, p. 1, doi. 10.1002/chem.202401531
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- Article
Cover Feature: sAPPα Peptide Promotes Damaged Microglia to Clear Alzheimer's Amyloid‐β via Restoring Mitochondrial Function (Chem. Eur. J. 40/2024).
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- Chemistry - A European Journal, 2024, v. 30, n. 40, p. 1, doi. 10.1002/chem.202402238
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- Publication type:
- Article
sAPPα Peptide Promotes Damaged Microglia to Clear Alzheimer's Amyloid‐β via Restoring Mitochondrial Function.
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- Chemistry - A European Journal, 2024, v. 30, n. 40, p. 1, doi. 10.1002/chem.202400870
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- Publication type:
- Article
Tyrosine‐Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal–Organic Framework Composites as Electrochemical Tags.
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- Chemistry - A European Journal, 2023, v. 29, n. 28, p. 1, doi. 10.1002/chem.202300450
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- Publication type:
- Article
Photoactive Bismuth Vanadate Structure for Light‐Triggered Dissociation of Alzheimer's β‐Amyloid Aggregates.
- Published in:
- Advanced Functional Materials, 2018, v. 28, n. 41, p. N.PAG, doi. 10.1002/adfm.201802813
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- Publication type:
- Article
Improvement of cerebral function by anti-amyloid precursor protein antibody infusion after traumatic brain injury in rats.
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- Molecular & Cellular Biochemistry, 2009, v. 324, n. 1/2, p. 191, doi. 10.1007/s11010-008-0013-1
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- Publication type:
- Article
Coupling enhanced sampling of the apo-receptor with template-based ligand conformers selection: performance in pose prediction in the D3R Grand Challenge 4.
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- Journal of Computer-Aided Molecular Design, 2020, v. 34, n. 2, p. 149, doi. 10.1007/s10822-019-00244-6
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- Publication type:
- Article
Computational insights into the selectivity mechanism of APP-IP over matrix metalloproteinases.
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- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 12, p. 1327, doi. 10.1007/s10822-012-9617-3
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- Publication type:
- Article
Population Study Confirms Serum Proteins' Change and Reveals Diagnostic Values in Congenital Ventricular Septal Defect.
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- Pediatric Cardiology, 2017, v. 38, n. 6, p. 1191, doi. 10.1007/s00246-017-1641-6
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- Publication type:
- Article
Relationships between the Bone Expression of Alzheimer's Disease-Related Genes, Bone Remodelling Genes and Cortical Bone Structure in Neck of Femur Fracture.
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- Calcified Tissue International, 2021, v. 108, n. 5, p. 610, doi. 10.1007/s00223-020-00796-y
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- Publication type:
- Article
Traumatic brain injury causes early aggregation of beta-amyloid peptides and NOTCH3 reduction in vascular smooth muscle cells of leptomeningeal arteries.
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- Acta Neuropathologica, 2025, v. 149, n. 1, p. 1, doi. 10.1007/s00401-025-02848-9
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- Publication type:
- Article
Autoantibodies to BACE1 promote Aβ accumulation and neurodegeneration in Alzheimer's disease.
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- Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02814-x
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- Publication type:
- Article
Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome.
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- Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02768-0
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- Publication type:
- Article
Associations of CSF BACE1 with amyloid pathology, neurodegeneration, and cognition in Alzheimer's disease.
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- Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02750-w
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- Publication type:
- Article
Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer's disease.
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- Acta Neuropathologica, 2023, v. 145, n. 6, p. 717, doi. 10.1007/s00401-023-02559-z
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- Publication type:
- Article
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.
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- Acta Neuropathologica, 2023, v. 145, n. 3, p. 325, doi. 10.1007/s00401-022-02533-1
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- Publication type:
- Article
Concussion leads to widespread axonal sodium channel loss and disruption of the node of Ranvier.
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- Acta Neuropathologica, 2022, v. 144, n. 5, p. 967, doi. 10.1007/s00401-022-02498-1
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- Publication type:
- Article
Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains.
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- Acta Neuropathologica, 2021, v. 141, n. 1, p. 39, doi. 10.1007/s00401-020-02234-7
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- Publication type:
- Article
The new genetic landscape of Alzheimer's disease: from amyloid cascade to genetically driven synaptic failure hypothesis?
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- Acta Neuropathologica, 2019, v. 138, n. 2, p. 221, doi. 10.1007/s00401-019-02004-0
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- Publication type:
- Article
SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data.
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- Acta Neuropathologica, 2019, v. 138, n. 2, p. 173, doi. 10.1007/s00401-019-01991-4
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- Publication type:
- Article
Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease.
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- Acta Neuropathologica, 2018, v. 136, n. 4, p. 569, doi. 10.1007/s00401-018-1866-3
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- Article
Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease.
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- Acta Neuropathologica, 2016, v. 132, n. 5, p. 653, doi. 10.1007/s00401-016-1615-4
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- Article
Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
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- Acta Neuropathologica, 2016, v. 132, n. 2, p. 235, doi. 10.1007/s00401-016-1558-9
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- Article
Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease.
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- Acta Neuropathologica, 2015, v. 130, n. 4, p. 487, doi. 10.1007/s00401-015-1477-1
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- Article
Beta-amyloid deposition in chronic traumatic encephalopathy.
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- Acta Neuropathologica, 2015, v. 130, n. 1, p. 21, doi. 10.1007/s00401-015-1435-y
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- Publication type:
- Article
Extracellular association of APP and tau fibrils induces intracellular aggregate formation of tau.
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- Acta Neuropathologica, 2015, v. 129, n. 6, p. 895, doi. 10.1007/s00401-015-1415-2
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- Article
The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes.
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- Acta Neuropathologica, 2015, v. 129, n. 1, p. 1, doi. 10.1007/s00401-014-1347-2
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- Publication type:
- Article
Traumatic brain injury-induced axonal phenotypes react differently to treatment.
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- Acta Neuropathologica, 2015, v. 129, n. 2, p. 317, doi. 10.1007/s00401-014-1376-x
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- Article
Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity.
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- Acta Neuropathologica, 2015, v. 129, n. 1, p. 21, doi. 10.1007/s00401-014-1368-x
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- Publication type:
- Article
Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice.
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- Acta Neuropathologica, 2014, v. 127, n. 5, p. 685, doi. 10.1007/s00401-014-1259-1
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- Publication type:
- Article
The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.
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- Acta Neuropathologica, 2013, v. 126, n. 3, p. 329, doi. 10.1007/s00401-013-1152-3
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- Article
Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons.
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- Acta Neuropathologica, 2013, v. 125, n. 4, p. 595, doi. 10.1007/s00401-013-1082-0
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- Publication type:
- Article
Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease.
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- Acta Neuropathologica, 2013, v. 125, n. 2, p. 201, doi. 10.1007/s00401-012-1062-9
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- Article
Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease.
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- Acta Neuropathologica, 2013, v. 125, n. 2, p. 187, doi. 10.1007/s00401-012-1065-6
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- Publication type:
- Article
AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies.
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- Acta Neuropathologica, 2011, v. 121, n. 3, p. 337, doi. 10.1007/s00401-010-0759-x
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- Publication type:
- Article
APP involvement in retinogenesis of mice.
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- Acta Neuropathologica, 2011, v. 121, n. 3, p. 351, doi. 10.1007/s00401-010-0762-2
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- Article
Tau pathology in children and young adults: can you still be unconditionally baptist?
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- 2011
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- Publication type:
- Editorial
Neuropathology after active Aβ42 immunotherapy: implications for Alzheimer’s disease pathogenesis.
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- Acta Neuropathologica, 2010, v. 120, n. 3, p. 369, doi. 10.1007/s00401-010-0719-5
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- Article
Autosomal dominant sensory ataxia: a neuroaxonal dystrophy.
- Published in:
- 2008
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- Publication type:
- Report
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
- Published in:
- Nature, 2015, v. 526, n. 7573, p. 443, doi. 10.1038/nature14864
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- Article
PLD3 variants in population studies.
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- Nature, 2015, v. 520, n. 7545, p. E2, doi. 10.1038/nature14038
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- Publication type:
- Article
Three-dimensional structure of human γ-secretase.
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- Nature, 2014, v. 512, n. 7513, p. 166, doi. 10.1038/nature13567
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- Publication type:
- Article
Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease.
- Published in:
- Nature, 2013, v. 500, n. 7460, p. 45, doi. 10.1038/nature12415
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- Publication type:
- Article