Works matching DE "FOCAL adhesion kinase"

Results: 1737

Drug Combinations Targeting FAK and MEK Overcomes Tumor Heterogeneity in Glioblastoma.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 549, doi. 10.3390/pharmaceutics17050549

By:

Furqan, Muhammad;
Elliott, Richard J. R.;
Nagle, Peter W. K.;
Dawson, John C.;
Masalmeh, Roza;
Garcia, Virginia Alvarez;
Munro, Alison F.;
Drake, Camilla;
Morrison, Gillian M.;
Pollard, Steven M.;
Ebner, Daniel;
Brunton, Valerie G.;
Frame, Margaret C.;
Carragher, Neil O.

Publication type:

Article

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 9, p. 984, doi. 10.1038/nsmb.2092

By:

Li-Zhi Mi;
Chafen Lu;
Zongli Li;
Nishida, Noritaka;
Walz, Thomas;
Springer, Timothy A.

Publication type:

Article

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 8, p. 876, doi. 10.1038/nsmb.1628

By:

Sang-Moon Yun;
Moulaei, Tinoush;
Lim, Dan;
Bang, Jeong K.;
Jung-Eun Park;
Shenoy, Shilpa R.;
Fa Liu;
Kang, Young H.;
Chenzhong Liao;
Nak-Kyun Soung;
Sunhee Lee;
Do-Young Yoon;
Yoongho Lim;
Dong-Hee Lee;
Otaka, Akira;
Appella, Ettore;
McMahon, James B.;
Nicklaus, Marc C.;
Burke Jr., Terrence R.;
Yaffe, Michael B.

Publication type:

Article

Phosphotyrosine enrichment identifies focal adhesion kinase and other tyrosine kinases for targeting in canine hemangiosarcoma.

Published in:

Veterinary & Comparative Oncology, 2012, v. 10, n. 3, p. 214, doi. 10.1111/j.1476-5829.2012.00325.x

By:

Marley, K.;
Maier, C. S.;
Helfand, S. C.

Publication type:

Article

Finding the Perfect Fit.

Published in:

Bio-IT World, 2004, v. 3, n. 4, p. 36

By:

Branca, Malorye A.

Publication type:

Article

Focal adhesion kinase (FAK): emerging target for drug-resistant malignant tumors.

Published in:

2025

By:

Aakriti, Jaya;
Vithalkar, Megh Pravin;
Maity, Swastika;
Baby, Krishnaprasad;
Nagareddy, Prabhakara R.;
Nayak, Yogendra

Publication type:

Literature Review

Resistance to gefitinib.

Published in:

International Journal of Clinical Oncology, 2006, v. 11, n. 6, p. 487, doi. 10.1007/s10147-006-0609-y

By:

Uramoto, Hidetaka;
Sugio, Kenji;
Oyama, Tsunehiro;
Sugaya, Masakazu;
Hanagiri, Takeshi;
Yasumoto, Kosei

Publication type:

Article

Induction of anoikis by doxazosin in prostate cancer cells is associated with activation of caspase-3 and a reduction of focal adhesion kinase.

Published in:

Urological Research, 2004, v. 32, n. 4, p. 261, doi. 10.1007/s00240-003-0365-7

By:

Walden, Paul D.;
Globina, Yelena;
Nieder, Alan

Publication type:

Article

Cryptotanshinone protects primary rat cortical neurons from glutamate-induced neurotoxicity via the activation of the phosphatidylinositol 3-kinase/Akt signaling pathway.

Published in:

Experimental Brain Research, 2009, v. 193, n. 1, p. 109, doi. 10.1007/s00221-008-1600-9

By:

Fangyan Zhang;
Wenhua Zheng;
Rongbiao Pi;
Zhengrong Mei;
Yingxia Bao;
Jie Gao;
Wenjie Tang;
Shaorui Chen;
Peiqing Liu

Publication type:

Article

Kinases and phosphatases in ischaemic preconditioning: a re-evaluation.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 4, p. 495, doi. 10.1007/s00395-010-0086-3

By:

Fan, W. J.;
van Vuuren, D.;
Genade, S.;
Lochner, Amanda

Publication type:

Article

LXR activation inhibits chemokine-induced CD4-positive lymphocyte migration.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 4, p. 487, doi. 10.1007/s00395-010-0092-5

By:

Walcher, Daniel;
Vasic, Dusica;
Heinz, Philipp;
Bach, Helga;
Durst, Renate;
Hausauer, Angelina;
Hombach, Vinzenz;
Marx, Nikolaus

Publication type:

Article

Exploitation of butyrate kinase and phosphotransbutyrylase from Clostridium acetobutylicum for the in vitro biosynthesis of poly(hydroxyalkanoic acid).

Published in:

Applied Microbiology & Biotechnology, 2000, v. 53, n. 5, p. 545, doi. 10.1007/s002530051655

By:

Liu, S.-J.;
Steinbüchel, A.

Publication type:

Article

Impact of Isolation Methods on Extracellular Vesicle Functionality In Vitro and In Vivo.

Published in:

Advanced Biology, 2024, v. 8, n. 2, p. 1, doi. 10.1002/adbi.202300185

By:

Balbi, Carolina;
Parisse, Pietro;
Vondracek, Hendrik;
Lazzarini, Edoardo;
Bolis, Sara;
Fertig, Tudor E.;
Gherghiceanu, Mihaela;
Barile, Lucio;
Vassalli, Giuseppe

Publication type:

Article

COL8A1 overexpression promotes glioma cell growth by activating focal adhesion kinase signaling cascade.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00762-z

By:

Qian, Jin;
Xing, Haihui;
Wang, Yin;
Li, Chen;
Chen, Hairong;
Rong, Jun;
Qian, Chunfa

Publication type:

Article

Ibrutinib reverses IL-6-induced osimertinib resistance through inhibition of Laminin α5/FAK signaling.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03111-7

By:

Li, Li;
Li, Zhujun;
Lu, Conghua;
Li, Jianghua;
Zhang, Kejun;
Lin, Caiyu;
Tang, Xiaolin;
Liu, Zhulin;
Zhang, Yimin;
Han, Rui;
Wang, Yubo;
Feng, Mingxia;
Zhuang, Yuan;
Hu, Chen;
He, Yong

Publication type:

Article

Natural killer cells: NK cells get their VA-VAVoom.

Published in:

Nature Reviews Immunology, 2011, v. 11, n. 7, p. 444, doi. 10.1038/nri3008

By:

Minton, Kirsty

Publication type:

Article

The influence of tag sequence on recombinant humanized collagen (rhCol) and the evaluation of rhCol on Schwann cell behaviors.

Published in:

Regenerative Biomaterials, 2023, v. 10, p. 1, doi. 10.1093/rb/rbad089

By:

Bai, Mingxuan;
Kang, Ning;
Xu, Yang;
Wang, Jing;
Shuai, Xinxing;
Liu, Caojie;
Jiang, Yixuan;
Du, Yu;
Gong, Ping;
Lin, Hai;
Zhang, Xingdong

Publication type:

Article

Mechanical Stretch Control of Adipocyte AKT Signaling and the Role of FAK and ROCK Mechanosensors.

Published in:

Bioengineering (Basel), 2024, v. 11, n. 12, p. 1279, doi. 10.3390/bioengineering11121279

By:

Bouzid, Tasneem;
Kim, Eunju;
Riehl, Brandon D.;
Yang, Ruiguo;
Saraswathi, Viswanathan;
Kim, Jason K.;
Lim, Jung Yul

Publication type:

Article

Cell–Biomaterial Interactions.

Published in:

Bioengineering (Basel), 2023, v. 10, n. 2, p. 241, doi. 10.3390/bioengineering10020241

By:

Deplaigne, Vincent;
Rochefort, Gael Y.

Publication type:

Article

Bioactive Scaffold Fabricated by 3D Printing for Enhancing Osteoporotic Bone Regeneration.

Published in:

Bioengineering (Basel), 2022, v. 9, n. 10, p. N.PAG, doi. 10.3390/bioengineering9100525

By:

Zhang, Xiaoting;
Wang, Xinluan;
Lee, Yuk-wai;
Feng, Lu;
Wang, Bin;
Pan, Qi;
Meng, Xiangbo;
Cao, Huijuan;
Li, Linlong;
Wang, Haixing;
Bai, Shanshan;
Kong, Lingchi;
Chow, Dick Ho Kiu;
Qin, Ling;
Cui, Liao;
Lin, Sien;
Li, Gang

Publication type:

Article

Cherry fruit anthocyanins cyanidin-3-O-glucoside and cyanidin-3-O-rutinoside protect against blue light-induced cytotoxicity in HaCaT cells.

Published in:

Applied Biological Chemistry, 2023, v. 66, n. 1, p. 1, doi. 10.1186/s13765-023-00767-5

By:

Lee, Hyang-Yeol;
Kim, Jun-Sub

Publication type:

Article

Thrombospondin-1-Induced Migration Is Functionally Dependent Upon Focal Adhesion Kinase.

Published in:

Vascular & Endovascular Surgery, 2008, v. 42, n. 3, p. 256, doi. 10.1177/1538574408314440

By:

Xiu-Jie Wang;
Maier, Kristopher;
Fuse, Shoichi;
Willis, Alliric I.;
Olson, Eric;
Nesselroth, Susan;
Sumpio, Bauer E.;
Gahtan, Vivian

Publication type:

Article

Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-Mediated Contractility via Activation of Focal Adhesion Kinase and Extracellular Regulated Kinase 1/2 in Cerebral Arteries from Rat.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2016, v. 119, n. 1, p. 68, doi. 10.1111/bcpt.12553

By:

Spray, Stine;
Rasmussen, Marianne N. P.;
Skovsted, Gry F.;
Warfvinge, Karin;
Sheykhzade, Majid;
Edvinsson, Lars

Publication type:

Article

崇明拟异小杆线虫 fak 基因的功能鉴定.

Published in:

Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao, 2021, v. 44, n. 2, p. 287, doi. 10.7685/jnau.202005003

By:

郭丹丹;
包浩然;
窦振国;
张克云

Publication type:

Article

Insulin-like growth factor-1 alters apoptotic signalling in prostate cancer.

Published in:

Prostate Cancer & Prostatic Diseases, 2000, v. 3, n. 1, p. S42, doi. 10.1038/sj.pcan.4500468

By:

Watson, RWG;
O'Brien, F;
Coffey, RNT;
Fitzpatrick, JM

Publication type:

Article

Differential expression of ORAI channels and STIM proteins in renal cell carcinoma subtypes: implications for metastasis and therapeutic targeting.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 1, p. 33, doi. 10.4196/kjpp.24.126

By:

Ji-Hee Kim;
Kyu-Hee Hwang;
Jiyeon Oh;
Sung-Eun Kim;
Mi-Young Lee;
Tae Sic Lee;
Seung-Kuy Cha

Publication type:

Article

Silencing MR-1 attenuates atherosclerosis in ApoE<sup>-/-</sup> mice induced by angiotensin II through FAK-Akt-mTOR-NF-kappaB signaling pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2018, v. 22, n. 2, p. 127, doi. 10.4196/kjpp.2018.22.2.127

By:

Yixi Chen;
Jianping Cao;
Qihui Zhao;
Haiyong Luo;
Yiguang Wang;
Wenjian Dai

Publication type:

Article

Focal adhesion kinase mediates porcine venular hyperpermeability elicited by vascular endothelial growth factor.

Published in:

Journal of Physiology, 2003, v. 552, n. 3, p. 691, doi. 10.1113/jphysiol.2003.048405

By:

Wu, Mack H.;
Mingzhang Guo, Mack H.;
Yuan, Sarah Y.;
Granger, Harris J.

Publication type:

Article

Progesterone and its metabolite allopregnanolone promote invasion of human glioblastoma cells through metalloproteinase‑9 and cSrc kinase.

Published in:

Oncology Letters, 2023, v. 25, n. 6, p. N.PAG, doi. 10.3892/ol.2023.13809

By:

Bello-Alvarez, Claudia;
Zamora-Sánchez, Carmen J.;
Peña-Gutiérrez, Karla M.;
Camacho-Arroyo, Ignacio

Publication type:

Article

Ursodeoxycholic acid inhibits epithelial-mesenchymal transition, suppressing invasiveness of bile duct cancer cells: An in vitro study.

Published in:

Oncology Letters, 2022, v. 24, n. 6, p. N.PAG, doi. 10.3892/ol.2022.13568

By:

Lee, Jin;
Hong, Eun Mi;
Kim, Jung Han;
Kim, Jung Hee;
Jung, Jang Han;
Park, Se Woo;
Koh, Dong Hee

Publication type:

Article

Shikonin inhibits the proliferation of cervical cancer cells via FAK/AKT/GSK3β signalling.

Published in:

Oncology Letters, 2022, v. 24, n. 3, p. N.PAG, doi. 10.3892/ol.2022.13424

By:

Xu, Ziyan;
Huang, Liru;
Zhang, Tiantian;
Liu, Yuwei;
Fang, Fang;
Wu, Xinyue;
Chen, Wen;
Lan, Lingning;
Zhang, Yangbo;
Li, Na;
Hu, Ping

Publication type:

Article

CORRIGENDUM.

Published in:: Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2020.12396
Publication type:: Article

Silencing glioma-associated oncogene homolog 1 suppresses the migration and invasion of hepatocellular carcinoma in vitro.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12091

By:

ZEMING HU;
FANGFANG XIE;
ANG HU;
MENGJING XU;
YUWEN LIU;
JIANKANG ZHANG;
JIANBO XIAO;
YUNLEI SONG;
JIANING ZHONG;
BIN CHEN

Publication type:

Article

Expression of ASAP1 and FAK in gastric cancer and its clinicopathological significance.

Published in:

Oncology Letters, 2020, v. 20, n. 1, p. 974, doi. 10.3892/ol.2020.11612

By:

Luo, Qiong;
Zhang, Suyun;
Zhang, Donghuan;
Yuan, Fang;
Chen, Xiangqi;
Yang, Sheng

Publication type:

Article

ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK.

Published in:

Oncology Letters, 2019, v. 17, n. 6, p. 5251

By:

More, Shyam K.;
Vomhof-Dekrey, Emilie E.;
Basson, Marc D.

Publication type:

Article

Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer.

Published in:

Oncology Letters, 2019, v. 17, n. 6, p. 4779

By:

Nolasco-Quiroga, Manuel;
Rosas-Díaz, Marisol;
Moreno, José;
Godínez-Aguilar, Ricardo;
López-Ibarra, María José;
Piña-Sánchez, Patricia;
Alvarado-Cabrero, Isabel;
Vázquez-Gómez, Gerardo;
Rocha-Zavaleta, Leticia;
Arenas-Aranda, Diego;
Salamanca-Gómez, Fabio

Publication type:

Article

MicroRNA-525 enhances chondrosarcoma malignancy by targeting F-spondin 1.

Published in:

Oncology Letters, 2019, v. 17, n. 1, p. 781

By:

Liu, Bo;
Song, Xiandong;
Yan, Zhaowei;
Yang, Hao;
Shi, Yingchao;
Wu, Jintao

Publication type:

Article

Overexpression of CD155 relates to metastasis and invasion in osteosarcoma.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 7312, doi. 10.3892/ol.2018.8228

By:

Zhuo, Baobiao;
Li, Yuan;
Gu, Feng;
Li, Zhengwei;
Sun, Qingzeng;
Shi, Yingchun;
Shen, Yang;
Zhang, Fengfei;
Wang, Rong;
Wang, Xiaodong

Publication type:

Article

LIM and SH3 protein 1 knockdown suppresses proliferation and metastasis of colorectal carcinoma cells via inhibition of the mitogen-activated protein kinase signaling pathway.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6839, doi. 10.3892/ol.2018.8222

By:

Zhao, Hongpeng;
Liu, Bo;
Li, Jie

Publication type:

Article

Focal adhesion kinase promotes progression and predicts poor clinical outcomes in patients with osteosarcoma.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 6225, doi. 10.3892/ol.2018.8152

By:

Gu, Hua-Jie;
Zhou, Bin

Publication type:

Article

Sodium butyrate induces senescence and inhibits the invasiveness of glioblastoma cells.

Published in:

Oncology Letters, 2018, v. 15, n. 2, p. 1495, doi. 10.3892/ol.2017.7518

By:

Nakagawa, Hidemitsu;
Sasagawa, Satoru;
Itoh, Kazuyuki

Publication type:

Article

Fibronectin induces epithelial-mesenchymal transition in human breast cancer MCF-7 cells via activation of calpain.

Published in:

Oncology Letters, 2017, v. 13, n. 5, p. 3889, doi. 10.3892/ol.2017.5896

By:

CHENG-LIN LI;
DAN YANG;
XIN CAO;
FAN WANG;
DUAN-YANG HONG;
JING WANG;
XIANG-CHUN SHEN;
YAN CHEN

Publication type:

Article

Interleukin-1β activates focal adhesion kinase and Src to induce matrix metalloproteinase-9 production and invasion of MCF-7 breast cancer cells.

Published in:

Oncology Letters, 2017, v. 13, n. 2, p. 955, doi. 10.3892/ol.2016.5521

By:

NAING NAING MON;
TAKESHI SENGA;
SATOKO ITO

Publication type:

Article

Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase.

Published in:

Oncology Letters, 2016, v. 12, n. 2, p. 1113, doi. 10.3892/ol.2016.4730

By:

YIBO FAN;
XIUJUAN QU;
YANJU MA;
YUNPENG LIU;
XUEJUN HU

Publication type:

Article

AURKA promotes cell migration and invasion of head and neck squamous cell carcinoma through regulation of the AURKA/Akt/FAK signaling pathway.

Published in:

Oncology Letters, 2016, v. 11, n. 3, p. 1889, doi. 10.3892/ol.2016.4110

By:

JICHANG WU;
LIYUN YANG;
YAMIN SHAN;
CHANGPING CAI;
SHILI WANG;
HAO ZHANG

Publication type:

Article

Expression of pY397 FAK promotes the development of non-small cell lung cancer.

Published in:

Oncology Letters, 2016, v. 11, n. 2, p. 979, doi. 10.3892/ol.2015.3992

By:

BAICHUN WANG;
XIUYING QI;
DANYANG LI;
MEIYAN FENG;
XIANGNING MENG;
SONGBIN FU

Publication type:

Article

Expression and clinical significance of focal adhesion kinase and adrenomedullin in epithelial ovarian cancer.

Published in:

Oncology Letters, 2015, v. 10, n. 2, p. 1003, doi. 10.3892/ol.2015.3278

By:

MINGQUN LI;
LI HONG;
MEIMEI LIAO;
GUANGLIN GUO

Publication type:

Article

Focal adhesion kinase is involved in the migration of human osteosarcoma cells.

Published in:

Oncology Letters, 2015, v. 9, n. 6, p. 2670, doi. 10.3892/ol.2015.3131

By:

SITAN FENG;
XIN SHI;
KE REN;
SUJIA WU;
XIAOLIANG SUN

Publication type:

Article

Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer.

Published in:

Oncology Letters, 2015, v. 9, n. 2, p. 595, doi. 10.3892/ol.2014.2725

By:

GUO-QIANG SU;
FU-XING ZHANG;
HE-HUI MAO;
XIAN-WEI LIU;
YONG-SHENG ZHENG;
SI-YU ZHANG;
JING-JUN SU

Publication type:

Article

Asiatic acid, a triterpene, inhibits cell proliferation through regulating the expression of focal adhesion kinase in multiple myeloma cells.

Published in:

Oncology Letters, 2013, v. 6, n. 6, p. 1762, doi. 10.3892/ol.2013.1597

By:

JUNLI ZHANG;
LISHA A. I.;
TINGTING L. V.;
XUDONG JIANG;
FANG LIU

Publication type:

Article