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- Title
Association of Beta-Thalassaemia and Hypogonadotropic Hypogonadism.
- Authors
Vidal, Angela; Dhakal, Carolin
- Abstract
Thalassaemic syndromes are among the most common haemoglobinopathies and are associated with high morbidity and mortality. Because of the various treatments, a secondary endocrinopathy due to iron overload—haemosiderosis—can occur, causing hypopituitarism leading to hypogonadotropic hypogonadism (HH) and infertility. We present a case of secondary amenorrhoea in a patient with beta-thalassaemia and a history of multiple therapies in her adolescence, such as multiple transfusions, chemotherapy, and allogeneic bone marrow transplantation, who presented with HH and premature ovarian insufficiency.
- Subjects
BETA-Thalassemia; HYPOGONADISM; PREMATURE ovarian failure; IRON overload; BONE marrow transplantation; HYPOPITUITARISM; PREMATURE menopause
- Publication
Case Reports in Obstetrics & Gynecology, 2022, p1
- ISSN
2090-6684
- Publication type
Academic Journal
- DOI
10.1155/2022/4655249