An Ultrasound Simulation Model for the Pulsatile Blood Flow Modulated by the Motion of Stenosed Vessel Wall.

Zhang, Qinghui; Zhang, Yufeng; Zhou, Yi; Zhang, Kun; Zhang, Kexin; Gao, Lian

This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of blood flow field modulated by wall motion. This model takes into account fluid-structure interaction, blood pulsatility, stenosis of the vessel, and arterial wall movement caused by surrounding tissue’s motion. The axial and radial velocity distributions of blood and the displacement of vessel wall are calculated by solving coupled Navier-Stokes and wall equations. With these obtained values, we made several different phantoms by treating blood and the vessel wall as a group of point scatterers. Then, ultrasound echoed signals from oscillating wall and blood in the axisymmetric stenotic-carotid arteries were computed by ultrasound simulation software, Field II. The results show better consistency with corresponding theoretical values and clinical data and reflect the influence of wall movement on the flow field. It can serve as an effective tool not only for investigating the behavior of blood flow field modulated by wall motion but also for quantitative or qualitative evaluation of new ultrasound imaging technology and estimation method of blood velocity.

ATHEROSCLEROSIS risk factors; BIOMECHANICS; BLOOD circulation; BLOOD flow measurement; HEMODYNAMICS; MATHEMATICS; RESEARCH funding; ULTRASONIC imaging; CAROTID artery stenosis; WAVE analysis; DATA analysis software; STATISTICAL models; DESCRIPTIVE statistics; DISEASE complications; DIAGNOSIS

BioMed Research International, 2016, Vol 2016, p1

2314-6133

Academic Journal

10.1155/2016/8502873