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- Title
Vomiting and Dysphagia Predict Delayed Gastric Emptying in Diabetic and Nondiabetic Subjects.
- Authors
Boltin, Doron; Zvidi, Ibrahim; Steinmetz, Adam; Bernstine, Hanna; Groshar, David; Nardi, Yuval; Boaz, Mona; Niv, Yaron; Dickman, Ram
- Abstract
Background. Gastroparesis is a heterogeneous disorder most often idiopathic, diabetic, or postsurgical in nature. The demographic and clinical predictors of gastroparesis in Israeli patients are poorly defined. Methods. During the study period we identified all adult patients who were referred to gastric emptying scintigraphy (GES) for the evaluation of dyspeptic symptoms. Of those, 193 patients who were referred to GES from our institution were retrospectively identified (76 (39%) males, mean age 60.2 } 15.6 years). Subjects were grouped according to gastric half-emptying times (gastric T1/2).Demographic and clinical data were extracted from electronic medical records or by a phone interview. Key Results. Gastric emptying half-times were normal (gastric T1/2 0-99 min) in 101 patients, abnormal (gastric T1/2 100-299 min) in 67 patients, and grossly abnormal (gastric T1/2 ≥ 300 min) in 25 patients. Vomiting and dysphagia, but neither early satiety nor bloating, correlated with delayed gastric emptying. Diabetes was associated with grossly abnormal gastric T1/2. Idiopathic gastroparesis was associated with a younger age at GES. No correlation was observed between gastric T1/2 values and gender, smoking, H. pylori infection, HBA1C, or microvascular complication of diabetes. Conclusions Inferences. Vomiting and dysphagia are predictive of delayed gastric emptying in both diabetic and nondiabetic subjects. Diabetes is associated with more severe gastroparesis.
- Subjects
GASTRIC emptying; DEGLUTITION disorders; GASTROPARESIS; MEDICAL care; INTESTINAL absorption
- Publication
Journal of Diabetes Research, 2014, p1
- ISSN
2314-6745
- Publication type
Academic Journal
- DOI
10.1155/2014/294032