The Padmakar–Ivan (PI) index of a graph G is defined as PI(G) = ∑[neu(e|G) nev(e|G)], where neu(e|G) is the number of edges of G lying closer to u than to v, nev(e|G) is the number of edges of G lying closer to v than to u and summation goes over all edges of G. In this paper, the PI and Szeged indices of T = VC5C7[4p, 8] nanotube is computed for the first time.