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Title

Cationic gemini surfactants as new agents for plasmid DNA delivery into cells.

Authors

Grigoriev, I.; Korobeinikov, V.; Cheresiz, S.; Pokrovsky, A.; Zakharova, L.; Voronin, M.; Lukashenko, S.; Konovalov, A.; Zuev, Yu.

Abstract

The article focuses on the role of alkylammonium gemine surfactants (AGSs) as an alternative agent for delivery of plasmid DNA into cells. It mentions that the structure of compounds was confirmed using elemental analysis and nuclear magnetic resonance (NMR). It notes that the binding of DNA to calixarenes and cationic surfactants leads to the substantial decrease in the fluorescence yield.

Subjects

SURFACE active agents; PLASMIDS; NUCLEAR magnetic resonance; CELLS; CALIXARENES; BIOCHEMISTRY; DNA

Publication

Doklady Biochemistry & Biophysics, 2012, Vol 445, Issue 1, p197

ISSN

1607-6729

Publication type

Academic Journal

DOI

10.1134/S1607672912040047

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