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- Title
Restoration of expression of MHC class I molecule in Walker 256 tumor in growth dynamics in Brattleboro rats.
- Authors
Afanasyeva, M.; Zakharova, L.; Khegai, I.; Sharova, N.; Popova, N.; Ivanova, L.; Melnikova, V.
- Abstract
The article focuses on the restoration of major histocompatibility complex (MHC) class I antigen expression in Walker 256 tumor in the growth dynamics in Brattleboro rats. It points out that the level of expression is identified by the proportion of cells expressing and not expressing MHC class I molecules. It explains that these molecules allow the tumor to escape from the immune control.
- Subjects
MAJOR histocompatibility complex; HISTOCOMPATIBILITY antigens; IMMUNOGENETICS; ISOANTIGENS; GENE expression; IMMUNOLOGIC diseases; BRATTLEBORO rat
- Publication
Doklady Biochemistry & Biophysics, 2010, Vol 430, Issue 1, p11
- ISSN
1607-6729
- Publication type
Academic Journal
- DOI
10.1134/S1607672910010047