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Title

Restoration of expression of MHC class I molecule in Walker 256 tumor in growth dynamics in Brattleboro rats.

Authors

Afanasyeva, M.; Zakharova, L.; Khegai, I.; Sharova, N.; Popova, N.; Ivanova, L.; Melnikova, V.

Abstract

The article focuses on the restoration of major histocompatibility complex (MHC) class I antigen expression in Walker 256 tumor in the growth dynamics in Brattleboro rats. It points out that the level of expression is identified by the proportion of cells expressing and not expressing MHC class I molecules. It explains that these molecules allow the tumor to escape from the immune control.

Subjects

MAJOR histocompatibility complex; HISTOCOMPATIBILITY antigens; IMMUNOGENETICS; ISOANTIGENS; GENE expression; IMMUNOLOGIC diseases; BRATTLEBORO rat

Publication

Doklady Biochemistry & Biophysics, 2010, Vol 430, Issue 1, p11

ISSN

1607-6729

Publication type

Academic Journal

DOI

10.1134/S1607672910010047

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