Title: α,β-Unsaturated β-Methyl-δ-lactones in Nitrile Oxide Cycloaddition Reactions. Synthesis of Saturated Lactones and Lactams.
Authors: Mineyeva, I. V.
Abstract: New isoxazoline derivatives have been synthesized in high yields by cycloaddition of acetonitrile oxide to α,β-unsaturated β-methyl-δ-lactones. These unsaturated lactones have been used to obtain β-methyl branched saturated lactones and lactams, as well as lactones with an inversed configuration of hydroxy group, following the divergent approach.
Subjects: LACTONES; LACTAMS; NITRILE oxides; RING formation (Chemistry); ISOXAZOLINE; ACETONITRILE
Publication: Russian Journal of Organic Chemistry, 2022, Vol 58, Issue 6, p765
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428022060033

α,β-Unsaturated β-Methyl-δ-lactones in Nitrile Oxide Cycloaddition Reactions. Synthesis of Saturated Lactones and Lactams.

Mineyeva, I. V.