Title: Reaction of Thioxanthylium Cation with Pharmacophoric Heterocyclic Amines.
Authors: Yunnikova, L. P.; Esenbaeva, V. V.; Danilova, E. A.; Islyaikin, M. K.
Abstract: Reactions of thioxanthylium tetrafluoroborate with pharmacophoric heterocyclic amines, pyrimidin-2-amine, 4,6-dimethylpyrimidin-2-amine, 2-aminopyrimidine-4,6-diol, and 1,3,4-thiadiazole-2,5-diamine, gave stable products of electrophilic substitution of one hydrogen atom per amino group. The product structure was confirmed by 1H NMR and mass spectra and X-ray analysis of N-(9H-tmoxanthen-9-yl)pyrimidin-2-amine.
Subjects: MASS spectrometry; THIADIAZOLES; AMINO group; HYDROGEN atom; AMINES; CATIONS; TETRAFLUOROBORATES
Publication: Russian Journal of Organic Chemistry, 2019, Vol 55, Issue 12, p1985
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428019120327

Reaction of Thioxanthylium Cation with Pharmacophoric Heterocyclic Amines.

Yunnikova, L. P.; Esenbaeva, V. V.; Danilova, E. A.; Islyaikin, M. K.