Title: Ring Opening of 4-Arylamino-2-tert-butyl-5-oxo-2,5-dihydrofuran-2-yl Acetates with Aromatic and Heterocyclic Amines.
Authors: Igidov, N. M.; Rubtsov, A. E.
Abstract: Reactions of 4-arylamino-2-tert-butyl-5-oxo-2,5-dihydrofuran-2-yl acetates with an equimolar amount of aromatic or heterocyclic amine in toluene involves initial attack of the amine on the C2 atom of the furan ring, followed by opening of the furan ring and elimination of acetic acid to give N-aryl(hetaryl)-2-arylamino-5,5-dimethyl-4-oxohex-2-enamides.
Subjects: ACETATES; ACETIC acid; AROMATIC amines; AMINES; TOLUENE; LACTONES
Publication: Russian Journal of Organic Chemistry, 2019, Vol 55, Issue 10, p1459
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428019100026

Ring Opening of 4-Arylamino-2-tert-butyl-5-oxo-2,5-dihydrofuran-2-yl Acetates with Aromatic and Heterocyclic Amines.

Igidov, N. M.; Rubtsov, A. E.