Title: Synthesis of 3,4-Dihydro-2H-[1,3]thiazino[3,2-c]quinazolinium Systems by Heterocyclization of 4-(Butenylsulfanyl)- and 4-(Cinnamylsulfanyl)qinazolines.
Authors: Bakhteeva, E. I.; Kim, D. G.; Dmitriev, M. V.; Krylova, Yu. E.
Abstract: The alkylation of quinazoline-4(3H)-thione with 4-bromobut-1-ene and cinnamyl chloride gave previously unknown 4-(but-3-en-1-ylsulfanyl)- and 4-(cinnamylsulfanyl)quinazolines which reacted with iodine and bromine to afford 3,4-dihydro-2H-[1,3]thiazino[3,2-c]quinazolin-5-ium salts. The structure of the products was studied by GC/MS, 1H NMR, and X-ray analysis.
Subjects: BROMINE; ALKYLATION; X-rays
Publication: Russian Journal of Organic Chemistry, 2019, Vol 55, Issue 6, p748
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428019060022

Synthesis of 3,4-Dihydro-2H-[1,3]thiazino[3,2-c]quinazolinium Systems by Heterocyclization of 4-(Butenylsulfanyl)- and 4-(Cinnamylsulfanyl)qinazolines.

Bakhteeva, E. I.; Kim, D. G.; Dmitriev, M. V.; Krylova, Yu. E.