Title: Synthesis of Hetarylquinolines from 2-{[(4-Methylquinolin-2-yl)sulfanyl]acetyl}-N-phenylhydrazine-1-carbothioamides.
Authors: Aleksanyan, I. L.; Hambardzumyan, L. P.
Abstract: Intramolecular cyclization of 2-{[(4-methyl(or 4,6- and 4,8-dimethyl)quinolin-2-yl)sulfanyl]-acetyl}-N-phenylhydrazine-1-carbothioamides in alkaline and acidic media afforded {[(4-methyl(or 4,6- and 4,8-dimethyl)quinolin-2-yl)sulfanyl]acetyl}-substituted 1,2,4-triazoles and 1,3,4-thiadiazoles. The reaction of these compounds with ethyl bromoacetate gave thiazolidinone derivatives.
Subjects: RING formation (Chemistry); CHEMICAL reactions; CHEMICAL derivatives; QUINOLINE; THIADIAZOLES
Publication: Russian Journal of Organic Chemistry, 2018, Vol 54, Issue 9, p1402
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428018090221

Synthesis of Hetarylquinolines from 2-{[(4-Methylquinolin-2-yl)sulfanyl]acetyl}-N-phenylhydrazine-1-carbothioamides.

Aleksanyan, I. L.; Hambardzumyan, L. P.