Title: Metallomicellar Complex of 1-Hexadecyl-4-aza-1-azoniabicyclo-[2.2.2]octane Bromide with Copper Dibromide for Solubilization of Nitrofurantoin.
Authors: Zhil’tsova, E. P.; Ibatullina, M. R.; Lukashenko, S. S.; Kutyreva, M. P.; Zakharova, L. Ya.
Abstract: Associates of amphiphilic 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide-copper dibromide complex solubilize nitrofurantoin (furadonin). The solubilizing capacity of premicellar aggregates with respect to nitrofurantoin is 15 times higher than that of micelles and is considerably higher (by a factor of 5-16) than the solubilizing effect of micellar solutions of the complex, ligand, and conventional cationic surfactants with respect to Orange OT.
Subjects: AMPHIPHILES; NITROFURANTOIN; MICELLES; CATIONIC surfactants; OCTANE
Publication: Russian Journal of Organic Chemistry, 2018, Vol 54, Issue 3, p431
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428018030107

Metallomicellar Complex of 1-Hexadecyl-4-aza-1-azoniabicyclo-[2.2.2]octane Bromide with Copper Dibromide for Solubilization of Nitrofurantoin.

Zhil’tsova, E. P.; Ibatullina, M. R.; Lukashenko, S. S.; Kutyreva, M. P.; Zakharova, L. Ya.