Title: Synthesis of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acids, intermediate products in the synthesis of cis-4-Aminochroman-3-ols.
Authors: Bredikhina, Z.; Pashagin, A.; Kurenkov, A.; Bredikhin, A.
Abstract: Oxidation of accessible ( R)-3-chloropropane-1,2-diol to ( R)-3-chloro-2-hydroxypropanoic acid and subsequent reaction of the latter with ortho-substituted sodium phenoxide gave a number of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acid which are intermediate products in the synthesis of nonracemic 4-aminochroman-3-ols.
Subjects: OXIDATION; AROMATIC compounds; ARENE epoxides; PHENOXIDES; ORGANIC chemistry
Publication: Russian Journal of Organic Chemistry, 2014, Vol 50, Issue 4, p535
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428014040150

Synthesis of enantiomerically pure 3-aryloxy-2-hydroxypropanoic acids, intermediate products in the synthesis of cis-4-Aminochroman-3-ols.

Bredikhina, Z.; Pashagin, A.; Kurenkov, A.; Bredikhin, A.