Title: Synthesis of 2-substituted aminothiazol-4(5 H)-ones proceeding from carboxylactones.
Authors: Kochikyan, T. V.; Samvelyan, M. A.; Arutyunyan, V. S.
Abstract: New representatives of 2,2,4-trisubstituted butano-4-lactones were synthesized. By a series of transformations the corresponding γ-carboxylactones were obtained. The latter served as starting compounds for preparation of heteryl-linked lactones, 5-[5-{(alkoxymethyl)-2-oxotetrahydrofuran-3-yl}methyl]-2-arylaminothiazol-4(5 H)-ones.
Subjects: LACTONES; THIAZOLES; ESTERS; ROCKET fuel; PROSTAGLANDINS; HETEROCYCLIC compounds
Publication: Russian Journal of Organic Chemistry, 2011, Vol 47, Issue 8, p1204
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428011080148

Synthesis of 2-substituted aminothiazol-4(5 H)-ones proceeding from carboxylactones.

Kochikyan, T. V.; Samvelyan, M. A.; Arutyunyan, V. S.