Title: Synthesis and some transformations of functionally substituted lactones.
Authors: Avetisyan, A. A.; Alvandzhyan, A. G.; Kostanyan, T. A.; Bidar, M. M.
Abstract: Reactions of functionally substituted unsaturated five- and six-membered cyanolactones with α- and β-hydroxy ketones in the presence of sulfuric acid gave substituted 2-oxofuran- and 2-oxopyran-3-carboxamides. Hydrolysis of some keto amides thus obtained afforded the corresponding carboxylic acids, and reactions with hydrazines and semicarbazides led to hydrazones and semicarbazones at the side-chain oxo group.
Subjects: LACTONES; KETONES; SULFURIC acid; FURANS; HYDROLYSIS; AMIDES; CARBOXYLIC acids
Publication: Russian Journal of Organic Chemistry, 2011, Vol 47, Issue 6, p910
ISSN: 1070-4280
Publication type: Academic Journal
DOI: 10.1134/S1070428011060133

Synthesis and some transformations of functionally substituted lactones.

Avetisyan, A. A.; Alvandzhyan, A. G.; Kostanyan, T. A.; Bidar, M. M.