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- Title
Uracyl derivatives functionalized with N-, S-, O-heterocycles.
- Authors
Krylova, E.; Semenov, V.; Galyametdinova, I.; Akamsin, V.; Sharafutdinova, D.; Reznik, V.
- Abstract
Reactions of 1,3-bis(bromopentyl)-5(6)-substituted uracyls with a series of five-membered heterocycles containing in the ring N, S, or O atoms and a mercapto group as a substituent at the carbon atom of the ring afforded uracyl derivatives of acyclic and macrocyclic structure with 2-thiobenzoxazole, 2-thio-5-methyl-1,3,4-thiadiazole, 2-thiobenzimidazole, and 2,5-dithio-1,3,4-thiadiazole fragments. N atoms of benzoxazole and imidazole fragments of compounds obtained undergo alkylation and quaternization with alkyl iodides and alkyl tosylates.
- Subjects
ALKYLATION; IMIDAZOLES; PROTON magnetic resonance; THIADIAZOLES; NITROGEN; SULFUR; OXYGEN
- Publication
Russian Journal of Organic Chemistry, 2011, Vol 47, Issue 5, p746
- ISSN
1070-4280
- Publication type
Academic Journal
- DOI
10.1134/S1070428011050149