Dicationic Imidazolium Surfactants with a Hydroxyl Substituent in the Spacer Fragment.

Kushnazarova, R. A.; Mirgorodskaya, A. B.; Mikhailov, V. A.; Belousova, I. A.; Zubareva, T. M.; Prokop'eva, T. M.; Voloshina, A. D.; Amerhanova, S. K.; Zakharova, L. Ya.

Dicationic imidazolium surfactants of the 1,1′-(2-hydroxypropan-1,3-diyl)bis(3-alkyl-1H-imidazol-3-ylium)chloride series with a variable hydrophobic chain length have been synthesized and characterized. The values of their critical micelle concentration have been determined by tensiometry, conductometry and spectrophotometry. Significant antimicrobial activity of these surfactants against a number of pathogenic bacteria and fungi was revealed. It was found that decyl and dodecyl derivatives turned out to be leader compounds, which surpassed reference antibiotics in their action and showed activity against resistant strains. The kinetic parameters reflecting the high catalytic effect of the tested dicationic imidazolium surfactants in the alkaline hydrolysis of 4-nitrophenyl esters of phosphonic, phosphoric, and toluenesulfonic acids have been obtained.

CATIONIC surfactants; CRITICAL micelle concentration; SURFACE active agents; CATALYSIS; PATHOGENIC fungi; PATHOGENIC bacteria

Russian Journal of General Chemistry, 2022, Vol 92, Issue 4, p659

1070-3632

Academic Journal

10.1134/S1070363222040077