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- Title
Pyrimidinophane p-toluenesulfonate—Water-soluble pyrimidine-containing macrocycles.
- Authors
Semenov, V. E.; Mikhailov, A. S.; Romanova, E. S.; Voloshina, A. D.; Kulik, N. V.; Uraleva, S. Yu.; Kozlov, A. V.; Latypov, Sh. K.; Reznik, V. S.
- Abstract
Reactions of pyrimidinophanes containing two 6-methylthiocytosine and one 6-methyluracil fragments with methyl p-toluenesulfonate gave amphiphilic macrocyclic bis- p-toluenesulfonates. Despite the presence of several reaction centers in the initial pyrimidinophane molecules, methylation occurred only at the N1 atom (with quaternization) of the 6-methylthiocytosine fragments. Bacteriostatic and fungistatic activity of the products was estimated.
- Subjects
PHYSICAL & theoretical chemistry; PYRIMIDINES; MOLECULES; METHYLATION; ANTIBACTERIAL agents; MACROCYCLIC compounds
- Publication
Russian Journal of General Chemistry, 2009, Vol 79, Issue 1, p134
- ISSN
1070-3632
- Publication type
Academic Journal
- DOI
10.1134/S1070363209010216