EBSCO Logo
Connecting you to content on EBSCOhost
Results
Title

Ultraviolet Photodissociation of Peptides: New Insight on the Mobile Proton Model.

Authors

Solovyeva, E. M.; Pereverzev, A. Y.; Gorshkov, M. V.; Boyarkin, O. V.

Abstract

In this work, we study the mechanism of peptide photodissociation by ultraviolet irradiation at 193 nm wavelength and discuss the role of ionization proton in this process. We found that substituting the ionization proton for the alkali metal cations (sodium) in the peptide ions results in significant changes of the photodissociation spectra. The experimental data obtained in this work revealed that the photodissociation process can be described using the mobile proton model introduced earlier for peptide collision dissociation. The results can be used in proteomics research for optimization of mass spectrometer's parameters to increase the efficiency of peptide dissociation and in developing sequence-specific models for peptide fragmentation prediction.

Subjects

PHOTODISSOCIATION; PROTONS; ALKALI metals; PEPTIDES; MASS spectrometers; COLLISION induced dissociation

Publication

Journal of Experimental & Theoretical Physics, 2020, Vol 130, Issue 4, p626

ISSN

1063-7761

Publication type

Academic Journal

DOI

10.1134/S1063776120030164

EBSCO Connect | Privacy policy | Terms of use | Copyright | Manage my cookies
Journals | Subjects | Sitemap
© 2025 EBSCO Industries, Inc. All rights reserved