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Title

How do chromosomes attach to synaptonemal complexes?

Authors

Spangenberg, V. E.; Dadashev, S. Ya.; Matveevsky, S. N.; Kolomiets, O. L.; Bogdanov, Yu. F.

Abstract

Fluorochrome-labeled oligonucleotides ( n = 44) corresponding to mouse genome repetitive sequences were hybridized in situ with pachytene nuclei of mouse spermatocytes. Signals of the repetitive sequences MaLR, MER, and (GT) were found to be dispersed through chromatin, and signals of B1 repeats and minisatellites were mostly attached to synaptonemal complexes immunostained with anti-SYCP3 antibodies. These results suggest that B1 repeats and minisatellites are candidates for sequences anchoring chromatin to synaptonemal complexes.

Subjects

OLIGONUCLEOTIDES; CHROMOSOMES; IMMUNOGLOBULINS; NUCLEOTIDE sequence; SPERMATOZOA

Publication

Russian Journal of Genetics, 2010, Vol 46, Issue 10, p1203

ISSN

1022-7954

Publication type

Academic Journal

DOI

10.1134/S1022795410100157

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