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Title

The Common Partner of Several Methyltransferases Modifying the Components of The Eukaryotic Translation Apparatus.

Authors

Vasilieva, E. N.; Laptev, I. G.; Sergiev, P. V.; Dontsova, O. A.

Abstract

Abstract: TRM112 is necessary for the activation and stability of several methyltransferases involved in the modification of various components of the translation apparatus. This unique protein is a partner for enzymes that methylate tRNA, rRNA, and the translation termination factor. Here we review the structural and functional features of the TRM112 complexes with methyltransferases and provide, where possible, information on their significance.

Subjects

METHYLTRANSFERASES; EUKARYOTES; GENETIC translation; RIBOSOMAL RNA; TRANSFER RNA; METHYLATION

Publication

Molecular Biology, 2018, Vol 52, Issue 6, p846

ISSN

0026-8933

Publication type

Academic Journal

DOI

10.1134/S0026893318060171

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