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- Title
The Common Partner of Several Methyltransferases Modifying the Components of The Eukaryotic Translation Apparatus.
- Authors
Vasilieva, E. N.; Laptev, I. G.; Sergiev, P. V.; Dontsova, O. A.
- Abstract
Abstract: TRM112 is necessary for the activation and stability of several methyltransferases involved in the modification of various components of the translation apparatus. This unique protein is a partner for enzymes that methylate tRNA, rRNA, and the translation termination factor. Here we review the structural and functional features of the TRM112 complexes with methyltransferases and provide, where possible, information on their significance.
- Subjects
METHYLTRANSFERASES; EUKARYOTES; GENETIC translation; RIBOSOMAL RNA; TRANSFER RNA; METHYLATION
- Publication
Molecular Biology, 2018, Vol 52, Issue 6, p846
- ISSN
0026-8933
- Publication type
Academic Journal
- DOI
10.1134/S0026893318060171